Researchers Hester den Ruijter

Hester den Ruijter

Full Professor

Strategic program(s):

Biography

Welcome to my page. Let me introduce myself, I am Hester den Ruijter, Professor of Cardiovascular disease in women. My aim is to translate knowledge from experimental research to the patient. In women, the diagnosis of heart disease is a problem. Most available diagnostics for heart disease have been tested in men and directly translated to women. Nowadays we are increasingly becoming aware that male-derived tests do not always detect heart disease in women. There are interesting sex differences in the pathophysiology of heart disease that may explain why diagnostic tests developed in men fail to detect heart disease in women. Therefore, my goal is to obtain novel biomarkers that facilitate the diagnosis of heart disease in women. If you have any questions regarding my research, you are welcome to contact me.

Strategic program(s):

Contact

hruijte2@umcutrecht.nl

Pure profile

Recent publications

All publications

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans Ernest Diez Benavente, Robin J G Hartman, Tim R Sakkers, Marian Wesseling, Yannicke Sloots, Lotte Slenders, Arjan Boltjes, Barend M Mol, Gert J de Borst, Dominique P V de Kleijn, Koen H M Prange, Menno P J de Winther, Johan Kuiper, Mete Civelek, Sander W van der Laan, Steve Horvath, Charlotte Onland-Moret, Michal Mokry, Gerard Pasterkamp, Hester M den Ruijter
Arteriosclerosis, Thrombosis, and Vascular Biology, 2024, vol. 44, p.1419-1431

ANOCA patients with and without coronary vasomotor dysfunction present with limited electrocardiographic remodeling Diantha J.M. Schipaanboord, Tijn P.J. Jansen, Caïa Crooijmans, N. Charlotte Onland-Moret, Suzette E. Elias-Smale, Aukelien C. Dimitriu-Leen, Pim van der Harst, Tim P. van de Hoef, René van Es, Peter Damman, Hester M. den Ruijter
IJC Heart and Vasculature, 2024, vol. 50

A critical appreciation of pathway analysis in atherosclerotic disease. Cellular phenotypic plasticity as an illustrative example M Wesseling, E Diez-Benavente, M Mokry, H M den Ruijter, G Pasterkamp
Vascular Pharmacology, 2024, vol. 154, p.1-5

Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum Karolina Andrzejczyk, Sabrina Abou Kamar, Anne-Mar van Ommen, Elisa Dal Canto, Teun B Petersen, Gideon Valstar, K Martijn Akkerhuis, Maarten Jan Cramer, Victor Umans, Frans H Rutten, Arco Teske, Eric Boersma, Roxana Menken, Bas M van Dalen, Leonard Hofstra, Marianne Verhaar, Jasper Brugts, Folkert Asselbergs, Hester den Ruijter, Isabella Kardys
Scientific Reports, 2024, vol. 14

IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice Santosh Karnewar, Vaishnavi Karnewar, Rebecca A. Deaton, Laura S. Shankman, Ernest D. Benavente, Corey M. Williams, Xenia Bradley, Gabriel F. Alencar, Gamze B. Bulut, Sara Kirmani, Richard A. Baylis, Eli R. Zunder, Hester M. Den Ruijter, Gerard Pasterkamp, Gary K. Owens
Arteriosclerosis, Thrombosis, and Vascular Biology, 2024, vol. 44, p.1379-1392

Atherosclerotic plaque-specific methylation biomarkers in plasma cell-free DNA of female and male patients with coronary artery disease Ernest Diez Benavente, Tim R Sakkers, Pim van der Harst, Hester M den Ruijter
European heart journal, 2024, vol. 45, p.2468-2470

External positions

Member of Dekker committee, Dutch Heart Foundation

Research Council Member, Swiss National Science Foundation SNF

Committee member Klinische Fellows, ZonMw

Supervisory committee member , Stichting LEEFH

Committee member , Health Holland