Profile photo Harrie Weinans

Harrie Weinans

Associate Professor

Strategic program(s):

Biography

Our stiff bones are held together by ligaments and tendons and carry the weight and transfer the large forces that are required for locomotion. Without these load bearing mechanical tissues we would look like a gelatin pudding. With aging or after trauma the delicate internal architecture of these connective tissues gets lost, which can result in e.g. cartilage damage and subsequent deterioration (osteoarthritis), loss of bone mass (osteoporosis) problematic healing of fractures or tendons. Bone and cartilage are load bearing structures and degeneration and regeneration in these tissues are continuously influenced by and adapted to the biomechanical demands. The major goal of my research is to investigate the degenerative processes in the skeletal structures and find methods to counterbalance this degeneration or even induce appropriate regeneration after the tissue is already diminished.

Harrie Weinans is minority shareholder of Uplanner BV and Replasia BV

Research groups

Utrecht Osteoarthritis Research - UROAR

Research aim

Our group studies osteoarthritis, from disease mechanisms to treatment strategies. Using a translational approach, we connect lab research to patient care, aiming to create effective diagnostic tools and patient-centered therapies.

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Recent publications

Radioimmunotherapy combating biofilm-associated infection in vitro Zijian Ye, Berend van der Wildt, F. Ruben H.A. Nurmohamed, J. Fred F.Hooning van Duyvenbode, Jos van Strijp, H. Charles Vogely, Marnix G.E.H. Lam, Ekaterina Dadachova, Harrie Weinans, Bart C.H. van der Wal, Alex J. Poot
Frontiers in medicine, 2024, vol. 11
Reliability and agreement of manual and automated morphological radiographic hip measurements F. Boel, N. S. Riedstra, J. Tang, D. F. Hanff, H. Ahedi, V. Arbabi, N. K. Arden, S. M.A. Bierma-Zeinstra, M. M.A. van Buuren, F. M. Cicuttini, T. F. Cootes, K. Crossley, D. Eygendaal, D. T. Felson, W. P. Gielis, J. Heerey, G. Jones, S. Kluzek, N. E. Lane, C. Lindner, J. Lynch, J. van Meurs, A. E. Nelson, A. B. Mosler, M. C. Nevitt, E. H. Oei, J. Runhaar, H. Weinans, R. Agricola
Osteoarthritis and Cartilage Open, 2024, vol. 6
Radiologic Assessment of Interbody Fusion Anneli A A Duits, Paul R van Urk, A Mechteld Lehr, Don Nutzinger, Maarten R L Reijnders, Harrie Weinans, Wouter Foppen, F Cuhmur Oner, Steven M van Gaalen, Moyo C Kruyt
JBJS reviews, 2024, vol. 12, p.1-11
Biomolecule and Ion Releasing Mesoporous Nanoparticles Azin Khodaei, Qaisar Nawaz, Zhengqing Zhu, Saber Amin Yavari, Harrie Weinans, Aldo R. Boccaccini
ACS Applied Materials and Interfaces, 2024, vol. 16
Trained innate immunity modulates osteoblast and osteoclast differentiation N R Rahmani, R Belluomo, M C Kruyt, D Gawlitta, L A B Joosten, H Weinans, M Croes
Stem cell reviews and reports, 2024, vol. 20, p.1121-1134
Femoroacetabular impingement syndrome in middle-aged individuals is strongly associated with the development of hip osteoarthritis within 10-year follow-up Rintje Agricola, Michiel M.A. Van Buuren, Joanne L. Kemp, Harrie Weinans, Jos Runhaar, Sita M.A. Bierma-Zeinstra
British Journal of Sports Medicine, 2024, vol. 58, p.1061-1067

External positions

HL, 1 dag per week - colleges, begeleiding afstudeerprojecten, research - TU Delft