Gisela Slaats

Assistant Professor

Strategic program(s):

Biography

Dr. Gisela Slaats studied Molecular Life Sciences with a major in Biomedicine at Wageningen University (WUR). Her PhD (cum laude, faculty of medicine UU) was performed in the laboratory of Prof. Marianne Verhaar and co-supervised by Prof. Nine Knoers and Dr. Rachel Giles. During her PhD she worked as a visiting student researcher at Stanford University School of Medicine. Gisela continued her work on renal ciliopathies as a postdoc in the laboratory of Prof. Bernhard Schermer at the University Hospital Cologne (Germany). Since 2022 she works as an assistant professor in the Regenerative Medicine Center Utrecht, department of Nephrology. Here, Gisela is using human kidney organoids in fundamental and translational research about genetic kidney diseases and aims to improve treatment strategies for kidney diseases. In addition, she is co-PI on the Horizon Europe TheRaCil project (2023), which is a consortium that works on therapies for renal ciliopathies.

Strategic program(s):

Contact

gslaats@umcutrecht.nl

Pure profile

Recent publications

All publications

Advances and potential of regenerative medicine in pediatric nephrology Gisela G Slaats, Junyu Chen, Elena Levtchenko, Marianne C Verhaar, Fanny Oliveira Arcolino
Pediatric Nephrology, 2023, vol. 39, p.383-395

Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease Laura R Claus, Chuan Chen, Jennifer Stallworth, Joshua L Turner, Gisela Slaats, Alexandra L Hawks, Holly Mabillard, Sarah R Senum, Sujata Srikanth, Heather Flanagan-Steet, Raymond J Louie, Josh Silver, Jordan Lerner-Ellis, Chantal Morel, Chloe Mighton, Frank Sleutels, Marjon van Slegtenhorst, Tjakko van Ham, Alice S Brooks, Eiske M Dorresteijn, Tahsin Stefan Barakat, Karin Dahan, Nathalie Demoulin, Eric Jean Goffin, Eric Olinger, Martin Larsen, Jens Michael Hertz, Marc R Lilien, Lena Obeidová, Tomas Seeman, Hillarey K Stone, Larissa Kerecuk, Mihai Gurgu, Fjodor A Yousef Yengej, Carola Me Ammerlaan, Maarten B Rookmaaker, Christian Hanna, R Curtis Rogers, Karen Duran, Edith Peters, John A Sayer, Gijs van Haaften, Peter C Harris, Kun Ling, Jennifer M Mason, Albertien M van Eerde, Richard Steet,
Kidney International, 2023, vol. 104, p.995-1007

Soft, Dynamic Hydrogel Confinement Improves Kidney Organoid Lumen Morphology and Reduces Epithelial-Mesenchymal Transition in Culture Floor A A Ruiter, Francis L C Morgan, Nadia Roumans, Anika Schumacher, Gisela G Slaats, Lorenzo Moroni, Vanessa L S LaPointe, Matthew B Baker
Advanced Science, 2022, vol. 9, p.e2200543

Primary cilia suppress Ripk3-mediated necroptosis Emilia Kieckhöfer, Gisela G Slaats, Lena K Ebert, Marie-Christine Albert, Claudia Dafinger, Hamid Kashkar, Thomas Benzing, Bernhard Schermer
Cell death discovery, 2022, vol. 8

Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis Manaswita Jain, Rainer W J Kaiser, Katrin Bohl, Martin Hoehne, Heike Göbel, Malte P Bartram, Sandra Habbig, Roman-Ulrich Müller, Agnes B Fogo, Thomas Benzing, Bernhard Schermer, Katja Höpker, Gisela G Slaats
Kidney International, 2019, vol. 95, p.846-858

CiliaCarta Teunis J P van Dam, Julie Kennedy, Robin van der Lee, Erik de Vrieze, Kirsten A Wunderlich, Suzanne Rix, Gerard W Dougherty, Nils J Lambacher, Chunmei Li, Victor L Jensen, Michel R Leroux, Rim Hjeij, Nicola Horn, Yves Texier, Yasmin Wissinger, Jeroen van Reeuwijk, Gabrielle Wheway, Barbara Knapp, Jan F Scheel, Brunella Franco, Dorus A Mans, Erwin van Wijk, François Képès, Gisela G Slaats, Grischa Toedt, Hannie Kremer, Heymut Omran, Katarzyna Szymanska, Konstantinos Koutroumpas, Marius Ueffing, Thanh-Minh T Nguyen, Stef J F Letteboer, Machteld M Oud, Sylvia E C van Beersum, Miriam Schmidts, Philip L Beales, Qianhao Lu, Rachel H Giles, Radek Szklarczyk, Robert B Russell, Toby J Gibson, Colin A Johnson, Oliver E Blacque, Uwe Wolfrum, Karsten Boldt, Ronald Roepman, Victor Hernandez-Hernandez, Martijn A Huynen
PLoS ONE, 2019, vol. 14