Profile photo Gert Jan de Borst

Gert Jan de Borst

Full Professor

Biography

Gert Jan de Borst was born in Utrecht , the Netherlands on December 14th, 1970. Following medical school at the University of Utrecht he obtained his medical degree at the University of Utrecht in 1996 and graduated in September 1999. Subsequently he became a research fellow at the Department of Vascular Surgery of the University Medical Center (UMC) Utrecht where he participated in a substudy of the Dutch Bypass Oral anticoagulant or aspirin study (BOA trial). In the same period he performed animal experiments on endovascular venous valve transplantation.

In 2001 he started his residency in general surgery at the department of Surgery (Prof dr IHM Borel Rinkes). Between January 2007 and December 2009 he did a fellowship in Vascular Surgery  (Prof dr FL Moll). Within this timeframe he finished his PhD on carotid artery revascularization in August 2007.

Since april 2009 he works as a vascular surgeon at the department of Vascular Surgery of the UMC Utrecht. He is actively involved in the training of surgical residents (co-supervisor) and training of vascular fellows (supervisor). His area of main clinical and research interest is cerebrovascular pathology. As a result, most of his research activities focus on carotid artery revascularization. In February 2015 he had 161 Pubmed registered publications, and in may 2015 he will be co-promotor for the eighth PhD student defending her thesis. 

Besides, he is the director of the vascular animal experimental laboratory in Utrecht. He is associate editor of the European Journal of Vascular and Endovascular Surgery, and editor of the Journal of Endovascular Therapy and Journal of Cardiovascular Surgery. Furthermore, he is regular reviewer for the most relevant journals in his field of expertise (JAMA, Stroke, Journal of Neurology, Journal of Vascular Surgery, etc). Since 2012 he is secretary of the Dutch Association of Vascular Surgeons.

He is married with three kids and lives in Bilthoven, the Netherlands.

Research groups

Therapy of atherosclerosis and aneurysms

Research aim

Development and validation of image guided interventions, medical devices and pharmaceutical interventions (eg anti-inflammatory/coagulation) to improve outcome of atherosclerotic disease and aneurysms

Go to group

Recent publications

Proteomic profiling reveals a higher presence of glycolytic enzymes in human atherosclerotic lesions with unfavourable histological characteristics Kaylin C A Palm, Xiaoke Yin, Ferheen Baig, Konstantinos Theofilatos, Sander W van der Laan, Gert J de Borst, Dominique P V de Kleijn, Johann Wojta, Stefan Stojkovic, Manuel Mayr, Hester M den Ruijter, Gerard Pasterkamp, Ernest Diez Benavente, Michal Mokry
Cardiovascular research, 2025, vol. 121, p.1187-1203
Endothelial-to-mesenchymal transition gene signature derived from single-cell transcriptomics of human atherosclerotic tissue associates with stable plaque histological characteristics Lotte Slenders, Marian Wesseling, Siting Wei, Arjan Boltjes, Daniek M C Kapteijn, Petra van de Kraak, Marie A C Depuydt, Koen Prange, Noortje A M van den Dungen, Ernest Diez Benavente, Dominique P V de Kleijn, Gert J de Borst, Menno de Winther, Hester M den Ruijter, Gary K Owens, Gerard Pasterkamp, Michal Mokry
Vascular Pharmacology, 2025, vol. 159
Intraplaque haemorrhage quantification and molecular characterisation using attention based multiple instance learning Francesco Cisternino, Yipei Song, Tim S Peters, Roderick Westerman, Gert J de Borst, Ernest Diez Benavente, Noortje A M van den Dungen, Petra H van der Kraak, Dominique De Kleijn, Joost M Mekke, Michal Mokry, Gerard Pasterkamp, Hester M den Ruijter, Evelyn Velema, Clint L Miller, Craig A Glastonbury, Sander W van der Laan
2025
Silent brain ischemia within the TAXINOMISIS framework Vassiliki Kigka, Alessandro Carrozzi, Laura Ludovica Gramegna, Panagiotis K. Siogkas, Vassiliki Potsika, Vassilis Tsakanikas, Michael Kallmayer, Victor Obach, Vincente Riambau, Giovanni Spinella, Giovanni Pratesi, Luigi Cirillo, David Neil Manners, Rodolfo Pini, Gianluca Faggioli, Gert J. de Borst, George Galyfos, Frangiska Sigala, Perica Mutavdzic, Marija Jovanovic, Igor Koncar, Dimitros I. Fotiadis,
Frontiers in Neurology, 2024, vol. 15
Prediction of Severe Baseline Asymptomatic Carotid Stenosis and Subsequent Risk of Stroke and Cardiovascular Disease Michiel H.F. Poorthuis, Steven H.J. Hageman, Aernoud T.L. Fiolet, L. Jaap Kappelle, Michiel L. Bots, Ph Gabriel Steg, Frank L.J. Visseren, Deepak L. Bhatt, Gert J. De Borst
Stroke, 2024, vol. 55, p.2632-2640
A Nationwide Analysis in France on Sex Difference and Outcomes Following Carotid Intervention in Asymptomatic Patients Fabien Lareyre, Juliette Raffort, Riikka Tulamo, Gert J. de Borst, Christian Alexander Behrendt, Christian Pradier, Roxane Fabre, Laurent Bailly
Journal of Clinical medicine, 2024, vol. 13

Fellowships & Awards

NVVG-MSD prijs 2013

FP 7 Health Grant