Profile photo Frank Meye

Frank Meye

Associate Professor

Strategic program(s):

Biography

Neurophysiologist doing research on the brain's reward system in health and disease. Current focus on effects of stress on the (extended) dopamine neural circuitry, in relation to obesity, eating disorders and drug addiction. 

Strategic program(s):

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Research groups

Neural circuit plasticity and function

Research aim

The brain performs its functions through neural circuits: collections of interconnected cells (i.e. different types of neurons, and glial cells). We aim to unravel these circuits, understand how experiences alter them, and decipher their function.
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Neural circuit function

Research aim

We aim to unravel the neurobiology underlying eating disorders. This will provide a framework for the development of neurobiology-based therapeutic interventions for diseases like anorexia nervosa.
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Recent publications

GelMap Hugo G J Damstra, Josiah B Passmore, Albert K Serweta, Ioannis Koutlas, Mithila Burute, Frank J Meye, Anna Akhmanova, Lukas C Kapitein
Nature Methods, 2023, vol. 20, p.1573-1580
Characterizing and TRAPing a Social Stress-Activated Neuronal Ensemble in the Ventral Tegmental Area Ioannis Koutlas, Louisa E Linders, Stef E van der Starre, Inge G Wolterink-Donselaar, Roger A H Adan, Frank J Meye
Frontiers in Behavioral Neuroscience [E], 2022, vol. 16
Molecular signatures and cellular diversity during mouse habenula development Lieke L. van de Haar, Danai Riga, Juliska E. Boer, Oxana Garritsen, Youri Adolfs, Thomas E. Sieburgh, Roland E. van Dijk, Kyoko Watanabe, Nicky C.H. van Kronenburg, Mark H. Broekhoven, Danielle Posthuma, Frank J. Meye, Onur Basak, R. Jeroen Pasterkamp
Cell Reports, 2022, vol. 40, p.1-32
Studying Synaptic Connectivity and Strength with Optogenetics and Patch-Clamp Electrophysiology Louisa E Linders, Laura F Supiot, Wenjie Du, Roberto D'Angelo, Roger A H Adan, Danai Riga, Frank J Meye
International journal of molecular sciences, 2022, vol. 23
Systemic Injection of Aged Blood Plasma in Adult C57BL/6 Mice Induces Neurophysiological Impairments in the Hippocampal CA1 Christiaan F M Huffels, Roland E van Dijk, Henk Karst, Frank J Meye, Elly M Hol, Jinte Middeldorp
Journal of Alzheimer's Disease, 2022, vol. 89, p.283-297
Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal prostaglandin E2 modulatory effects Enrica Montalban, Albert Giralt, Lieng Taing, Evelien H S Schut, Laura F Supiot, Laia Castell, Yuki Nakamura, Benoit de Pins, Assunta Pelosi, Laurence Goutebroze, Pola Tuduri, Wei Wang, Katrina Daila Neiburga, Letizia Vestito, Julien Castel, Serge Luquet, Angus C Nairn, Denis Hervé, Nathaniel Heintz, Claire Martin, Paul Greengard, Emmanuel Valjent, Frank J Meye, Nicolas Gambardella, Jean-Pierre Roussarie, Jean-Antoine Girault
Molecular Psychiatry, 2022, vol. 27, p.2068-2079