Frank Huygen

Full Professor

Research groups

Chronification of pain - Clinical Research

Research aim

Our group aims to integrate fundamental research and clinical pain studies with a focus on neuroinflammation to design strategies preventing and reversing the transition from acute to chronic pain in patients.

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Chronification of pain - Neuroimmunology of pain

Research aim

Our research groups integrate fundamental research and clinical pain studies to understand the neurobiology of chronic pain. We focus on the interactions between the immune system and the nervous system to defeat chronic pain.

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Recent publications

Response to Elisabeth J M Adriaansen, Albert J M van Wijck, Steven P Cohen, Frank J P M Huygen, Mienke Rijsdijk
Pain Practice, 2025, vol. 25, p.1-2
Identifying Patient Subgroups in the Heterogeneous Chronic Pain Population Using Cluster Analysis Mienke Rijsdijk, Hidde M Smits, Hazal R Azizoglu, Sylvia Brugman, Yoeri van de Burgt, Tessa C van Charldorp, Dewi J van Gelder, Janny C de Grauw, Eline A van Lange, Frank J Meye, Madelijn Strick, Hedi W A Walravens, Laura H H Winkens, Frank J P M Huygen, Julia Drylewicz, Hanneke L D M Willemen
The Journal of Pain, 2025, vol. 28
Sensory alterations and immunological changes during the chronification of postsurgical pain Marjelle E C van Driel, Nadine van Veenendaal, Lisette Margaretha Vernooij, Niels Eijkelkamp, Leo Koenderman, L Timmerman, Roel J H Custers, Diyar Delawi, Frank J P M Huygen, M Rijsdijk
BMJ Open, 2025, vol. 15
12. vascular pain Ischemic pain in the extremities and Raynaud's syndrome Antal van der Gaag, Steven P. Cohen, Milan P. Stojanovic, Frank J.P.M. Huygen, Jan Willem Kallewaard
Pain Practice, 2024, vol. 25
Herpes zoster and post herpetic neuralgia Elisabeth J.M. Adriaansen, Julien G. Jacobs, Lisette M. Vernooij, Albert J.M. van Wijck, Steven P. Cohen, Frank J.P.M. Huygen, Mienke Rijsdijk
Pain Practice, 2024, vol. 25

External positions

Course director Neuromodulation academy - Cursus voor junior medisch specialisten voor neurostimulatie - ABBOTT