Frank Huygen

Full Professor

Research groups

Chronification of pain - Clinical Research

Research aim

Our group aims to integrate fundamental research and clinical pain studies with a focus on neuroinflammation to design strategies preventing and reversing the transition from acute to chronic pain in patients.

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Chronification of pain - Neuroimmunology of pain

Research aim

Our research groups integrate fundamental research and clinical pain studies to understand the neurobiology of chronic pain. We focus on the interactions between the immune system and the nervous system to defeat chronic pain.

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Recent publications

Differences in corneal nerve fiber density and fiber length in patients with painful chronic idiopathic axonal polyneuropathy and diabetic polyneuropathy Mariska D. Nieuwenhoff, Hoang Ton Nguyen, Sjoerd P. Niehof, Frank J.P.M. Huygen, Ajay Verma, Erica S. Klaassen, Malik Bechakra, Wouter J. Geelhoed, Joost L.M. Jongen, Annette C. Moll, Alexander F.J.E. Vrancken, Axel Petzold, Geert Jan Groeneveld
Muscle and Nerve, 2024, vol. 70, p.782-790
Development and validation of a multivariable prediction model for early prediction of chronic postsurgical pain in adults Marjelle E C van Driel, Jacqueline F M van Dijk, Sara J Baart, Winfried Meissner, Frank J P M Huygen, Mienke Rijsdijk
British Journal of Anaesthesia, 2022, vol. 129, p.407-415
Status quo of pain-related patient-reported outcomes and perioperative pain management in 10,415 patients from 10 countries Ruth Zaslansky, Philipp Baumbach, Marcus Komann, Winfried Meissner, Claudia Weinmann, Weidong Mi, Yanhong Liu, Yulong Ma, Yi Feng, Bailin Jiang, Dong Liang Mu, Rongtian Kang, Hongwei Wang, Tao Luo, Xiangdong Chen, Dong Yan, Qin Liao, Juan Yao, Li Li, Guiying Yang, Rianne van Boekel, Monique Steegers, Mienke Rijsdijk, Jacqueline van Dijk, Sjaak Rekker, Kees Olthof, Maurice J.M.M. Giezeman, Nick J. Koning, Myra Rinia, Juanita M. Cheuk-Alam, Leon Timmerman, Ana Lilia Garduño-López, Victor Manuel Acosta Nava, Lisette Castro Garcés, Dulce María Rascón-Martínez, Luis Felipe Cuellar-Guzmán, Maria Esther Flores-Villanueva, Elizabeth Villegas-Sotelo, Orlando Carrillo-Torres, Hugo Vilchis-Sámano, Mariana Calderón-Vidal, Gabriela Islas-Lagunas, Dusica Stamenkovic, Suzana Bojic, Jasna Gacic, Aleksandra Jukic, Emilija Dubljanin Raspopovic, Ivan Palibrk, Mauricio Polanco-García, Frank J.M. Huygen, , , , , , , , , , ,
European Journal of Pain (United Kingdom), 2022, vol. 26, p.2120-2140
Development and validation of a multivariable prediction model for the early prediction of chronic postsurgical pain. Response to Br J Anaesth 2022; 129 Marjelle van Driel, Frank Huygen, Mienke Rijsdijk
British Journal of Anaesthesia, 2022, vol. 130, p.e190-e191
Postoperative Pain and Age Jacqueline F M van Dijk, Ruth Zaslansky, Regina L M van Boekel, Juanita M Cheuk-Alam, Sara J Baart, Frank J P M Huygen, Mienke Rijsdijk
Anesthesiology, 2021, vol. 135, p.1104-1119
Effectiveness of Epiduroscopy for Patients with Failed Back Surgery Syndrome Matthijs W Geudeke, Annelot C Krediet, Suleyman Bilecen, Frank J P M Huygen, Mienke Rijsdijk
Pain Practice, 2020, vol. 21, p.468-481

External positions

Course director Neuromodulation academy - Cursus voor junior medisch specialisten voor neurostimulatie - ABBOTT