Frank Huygen

Full Professor

Contact

fhuygen2@umcutrecht.nl

Pure profile

Research groups

Chronification of pain - Clinical Research

Research aim

Our group aims to integrate fundamental research and clinical pain studies with a focus on neuroinflammation to design strategies preventing and reversing the transition from acute to chronic pain in patients.

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Chronification of pain - Neuroimmunology of pain

Research aim

Our research groups integrate fundamental research and clinical pain studies to understand the neurobiology of chronic pain. We focus on the interactions between the immune system and the nervous system to defeat chronic pain.

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Recent publications

All publications

Narrative review of the efficacy and safety of the high-concentration (179mg) capsaicin patch in peripheral neuropathic pain with recommendations for clinical practice and future research Rainer Freynhagen, Ralf Baron, Frank Huygen, Serge Perrot
Pain reports, 2025, vol. 10

Identifying Patient Subgroups in the Heterogeneous Chronic Pain Population Using Cluster Analysis Mienke Rijsdijk, Hidde M Smits, Hazal R Azizoglu, Sylvia Brugman, Yoeri van de Burgt, Tessa C van Charldorp, Dewi J van Gelder, Janny C de Grauw, Eline A van Lange, Frank J Meye, Madelijn Strick, Hedi W A Walravens, Laura H H Winkens, Frank J P M Huygen, Julia Drylewicz, Hanneke L D M Willemen
The Journal of Pain, 2025, vol. 28

Response to Elisabeth J M Adriaansen, Albert J M van Wijck, Steven P Cohen, Frank J P M Huygen, Mienke Rijsdijk
Pain Practice, 2025, vol. 25, p.1-2

Sensory alterations and immunological changes during the chronification of postsurgical pain Marjelle E C van Driel, Nadine van Veenendaal, Lisette Margaretha Vernooij, Niels Eijkelkamp, Leo Koenderman, L Timmerman, Roel J H Custers, Diyar Delawi, Frank J P M Huygen, M Rijsdijk
BMJ Open, 2025, vol. 15

1. Lumbosacral radicular pain Laurens Peene, Steven P. Cohen, Jan Willem Kallewaard, Andre Wolff, Frank Huygen, Antal van de Gaag, Steegers Monique, Kris Vissers, Chris Gilligan, Jan Van Zundert, Koen Van Boxem
Pain Practice, 2024, vol. 24, p.525-552

Herpes zoster and post herpetic neuralgia Elisabeth J.M. Adriaansen, Julien G. Jacobs, Lisette M. Vernooij, Albert J.M. van Wijck, Steven P. Cohen, Frank J.P.M. Huygen, Mienke Rijsdijk
Pain Practice, 2024, vol. 25

External positions

Course director Neuromodulation academy - Cursus voor junior medisch specialisten voor neurostimulatie - ABBOTT