Profile photo Folkert Asselbergs

Folkert Asselbergs

Full Professor

Biography

Prof Dr. Folkert W. Asselbergs is Professor of Precision medicine at Institute of Health Informatics and the institute of Cardiovasculair Science, University College London, Director of the NIHR BRC UCL/UCLH Clinical and Research Informatics Unit, consultant cardiologist and Professor of Precision Medicine at University Medical Center Utrecht, University of Utrecht, the Netherlands, associate editor European Heart Journal, section digital health and innovation, Chair Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliance.nl). 

 

Professor Asselbergs published more than 500 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org), and CAPACITY-COVID ( https://capacity-covid.eu)  are the most prominent and recent ones. He is scientific coordinator of European IMI Bigdate@heart consortium (www.bigdata-heart.eu). Bigdata@heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insight driving drug development and personalized medicine through advanced big-data analytics. 

 

Recent publications

Influence of stressful life events and personality traits on PLN cardiomyopathy severity E van Drie, S E L Taal, A F Schmidt, T E Verstraelen, R de Brouwer, D Schoormans, P M C Mommersteeg, R A de Boer, A A M Wilde, F W Asselbergs, A F Baas, J P van Tintelen, L M van den Heuvel
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2024, vol. 26
Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum Karolina Andrzejczyk, Sabrina Abou Kamar, Anne-Mar van Ommen, Elisa Dal Canto, Teun B Petersen, Gideon Valstar, K Martijn Akkerhuis, Maarten Jan Cramer, Victor Umans, Frans H Rutten, Arco Teske, Eric Boersma, Roxana Menken, Bas M van Dalen, Leonard Hofstra, Marianne Verhaar, Jasper Brugts, Folkert Asselbergs, Hester den Ruijter, Isabella Kardys
Scientific Reports, 2024, vol. 14
Pulmonary artery pressure monitoring in chronic heart failure P R D Clephas, V W Zwartkruis, J Malgie, M W F van Gent, H P Brunner-La Rocca, M K Szymanski, V P van Halm, M L Handoko, W Kok, F W Asselbergs, R van Kimmenade, O Manintveld, N M D A van Mieghem, S L M A Beeres, M C Post, C J W Borleffs, R Tukkie, A Mosterd, G C M Linssen, R F Spee, M E Emans, T D J Smilde, J van Ramshorst, C Kirchhof, F Feenema-Aardema, C A da Fonseca, M van den Heuve, R Hazeleger, M van Eck, L van Heerebeek, H Boersma, M Rienstra, R A de Boer, J J Brugts
European heart journal, 2024, vol. 45, p.2954-2964
Contemporary guideline-directed medical therapy in de novo, chronic, and worsening heart failure patients Jishnu Malgie, Mariëlle I Wilde, Pascal R D Clephas, Mireille E Emans, Stefan Koudstaal, Jeroen Schaap, Arend Mosterd, Jan van Ramshorst, Alexander J Wardeh, Sandra van Wijk, Mieke van den Heuvel, Eric Wierda, C Jan Willem Borleffs, Colette Saraber, Saskia L M A Beeres, Roland van Kimmenade, Wouter Jansen Klomp, Robert Denham, Carlos A da Fonseca, IJsbrand T Klip, Olivier C Manintveld, Robert M A van der Boon, Clara E E van Ofwegen, Ayten Yilmaz, Ron Pisters, Gerard C M Linssen, Nikola Faber, Loek van Heerebeek, Julio E C van de Swaluw, Lex J Bouhuijzen, Marco C Post, Aaf F M Kuijper, Ka Wai Wu, Eugène A van Beek, Tim Hesselink, Lennaert Kleijn, Maurice J M Kurvers, René A Tio, Jorina Langerveld, Bas M van Dalen, J W Martijn van Eck, M Louis Handoko, Walter R M Hermans, Hetty J J Koornstra-Wortel, Mariusz K Szymanski, Dennis Rooker, Kenneth Tandjung, Sabine C M Eijsbouts, Folkert W Asselbergs, Peter van der Meer, Hans-Peter Brunner-La Rocca, Rudolf A de Boer, Jasper J Brugts
European Journal of Heart Failure, 2024, vol. 26, p.1549-1560
Soluble Suppression of Tumorigenicity-2 Predicts Mortality and Right Heart Failure in Patients With a Left Ventricular Assist Device Lieke Numan, Emmeke Aarts, Faiz Ramjankhan, Marish I.F. Oerlemans, Manon G. van der Meer, Nicolaas de Jonge, Anne Marie Oppelaar, Hans Kemperman, Folkert W. Asselbergs, Linda W. Van Laake
Journal of the American Heart Association, 2024, vol. 13
Digital Solutions to Optimize Guideline-Directed Medical Therapy Prescriptions in Heart Failure Patients Jelle P Man, Joanna Klopotowska, Folkert W Asselbergs, M Louis Handoko, Steven A J Chamuleau, Mark J Schuuring
Current Heart Failure Reports, 2024, vol. 21, p.147-161

External positions

Netherlands Heart Institute

University College London