Profile photo Folkert Asselbergs

Folkert Asselbergs

Full Professor

Biography

Prof Dr. Folkert W. Asselbergs is Professor of Precision medicine at Institute of Health Informatics and the institute of Cardiovasculair Science, University College London, Director of the NIHR BRC UCL/UCLH Clinical and Research Informatics Unit, consultant cardiologist and Professor of Precision Medicine at University Medical Center Utrecht, University of Utrecht, the Netherlands, associate editor European Heart Journal, section digital health and innovation, Chair Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliance.nl). 

 

Professor Asselbergs published more than 500 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org), and CAPACITY-COVID ( https://capacity-covid.eu)  are the most prominent and recent ones. He is scientific coordinator of European IMI Bigdate@heart consortium (www.bigdata-heart.eu). Bigdata@heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insight driving drug development and personalized medicine through advanced big-data analytics. 

 

Recent publications

Dietary patterns in Tanzania’s transitioning rural and urban areas Linda Simon Paulo, Virissa C. Lenters, Pilly Chillo, Milka Wanjohi, Gonçalo J. Piedade, Daniel R. Mende, Vanessa Harris, Appolinary Kamuhabwa, Gideon Kwesigabo, Folkert W. Asselbergs, K. Klipstein-Grobusch
Journal of Health, Population and Nutrition, 2025, vol. 44
Rationale and design of the HOVON 170 DLBCL-ANTICIPATE trial Marijke Linschoten, Jesse Geels, Erik van Werkhoven, Heleen Visser-Wisselaar, Martine E D Chamuleau, Arco J Teske, Lourens Robbers, Simone Oerlemans, Heleen Crommelin, Marleen Breems-de Ridder, Astrid Schut, Folkert W Asselbergs, Anna van Rhenen,
Cardio-oncology (London, England), 2025, vol. 11
An hiPSC-CM approach for electrophysiological phenotyping of a patient-specific case of short-coupled TdP Willem B. van Ham, Esmeralda E.M. Meijboom, Merel L. Ligtermoet, Jantine Monshouwer-Kloots, Anneline S.J.M.te Riele, Folkert W. Asselbergs, Eva van Rooij, Mimount Bourfiss, Toon A.B. van Veen
Stem Cell Research and Therapy, 2024, vol. 15
Recreational and Occupational Physical Activity and Risk of Adverse Events in Truncating MYBPC3 Founder Variant Carriers. Fahima Hassanzada, Mark Jansen, Freyja H M van Lint, Laurens P Bosman, Amand F Schmidt, Dennis Dooijes, Danny van de Sande, Bristi Miah, Saskia N van der Crabben, Arthur A M Wilde, Ronald H Lekanne Deprez, Rudolf A de Boer, Imke Christiaans, Jan D H Jongbloed, Harald T Jorstad, Folkert W Asselbergs, J Peter van Tintelen, Annette F Baas, Anneline S J M Te Riele
Circulation. Genomic and precision medicine, 2024, vol. 17
Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy Sean L. Zheng, Albert Henry, Douglas Cannie, Michael Lee, David Miller, Kathryn A. McGurk, Isabelle Bond, Xiao Xu, Hanane Issa, Catherine Francis, Antonio De Marvao, Pantazis I. Theotokis, Rachel J. Buchan, Doug Speed, Erik Abner, Lance Adams, Krishna G. Aragam, Johan Ärnlöv, Anna Axelsson Raja, Joshua D. Backman, John Baksi, Paul J.R. Barton, Kiran J. Biddinger, Eric Boersma, Jeffrey Brandimarto, Søren Brunak, Henning Bundgaard, David J. Carey, Philippe Charron, James P. Cook, Stuart A. Cook, Spiros Denaxas, Jean François Deleuze, Alexander S. Doney, Perry Elliott, Christian Erikstrup, Tõnu Esko, Eric H. Farber-Eger, Chris Finan, Sophie Garnier, Jonas Ghouse, Vilmantas Giedraitis, Daniel F. Guðbjartsson, Vinicius Tragante, Jessica van Setten, Marion van Vugt, W. M.Monique Verschuren, Marion van Vugt, Folkert W. Asselbergs, , , ,
Nature genetics, 2024, vol. 56, p.2646–2658
Validation of machine learning-based risk stratification scores for patients with acute coronary syndrome treated with percutaneous coronary intervention Mitchel A. Molenaar, Jasper L. Selder, Amand F. Schmidt, Folkert W. Asselbergs, Jelle D. Nieuwendijk, Brigitte van Dalfsen, Mark J. Schuuring, Berto J. Bouma, Steven A.J. Chamuleau, Niels J. Verouden
European Heart Journal - Digital Health, 2024, vol. 5, p.702-711

Fellowships & Awards

2003 Dr. E. Dekker Scholarship of the Dutch Heart Foundation (2003T010).
2005 Scholarship Netherlands Heart Institute for postdoc Harvard School of public health
2007 Netherlands Foundation of CardioVascular Excellence grant
2010 Clinical fellowship from the Netherlands Organisation for Health Research (ZonMw grant 90700342),
2012 European Society of Cardiology Training grant (T2012-006).
2013 Fellow European Society of Cardiology
2014 Dr. E. Dekker Scholarship of the Dutch Heart Foundation (2014T001)
2019 Scholarship European Society of Cardiology Executive Master Health Economics at LSE
2021 Pearl award ZonMw, Netherlands: www.zonmw.nl/nl/actueel/parelprojecten/parel-voorbruggenbouwer-in-hartfalen-onderzoek/

External positions

editorship - peer-reviewed vakblad binnen vakgebied - associate editor European Heart Journal, digital health

Bestuur DutchCardioVacularAlliance (www.dcvalliance.nl) met portfolio Data Infrastructure - DCVA is subsidiegever en strategisch verantwoordelijk voor nieuwe nationale CVD onderzoekslijnen - DutchCardioVascularAlliance