Ewout Groen

Assistant Professor

Strategic program(s):

Contact

egroen3@umcutrecht.nl

Pure profile

Research groups

Research in Spinal Muscular Atrophy

Research aim

The Netherlands SMA Center is the single dedicated center for SMA in the Netherlands, including newborn screening, diagnostics, care, treatments and scientific research. We conduct various national and internal clinical trials and studies.

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Recent publications

All publications

Comprehensive analysis across SMN2 excludes DNA methylation as an epigenetic biomarker for spinal muscular atrophy Maria M. Zwartkruis, Joris V. Kortooms, Demi Gommers, Martin G. Elferink, Ilaria Signoria, Joyce van der Sel, Paul J. Hop, Ramona A.J. Zwamborn, Robin Geene, Jared W. Green, Hanneke W.M. van Deutekom, Wouter van Rheenen, Jan H. Veldink, Fay Lynn Asselman, Renske I. Wadman, W. Ludo van der Pol, Gijs W. van Haaften, Ewout J.N. Groen
iScience, 2025, vol. 28

Dynamic modulation of the motor neuron translatome during developmental synapse elimination Dinja van der Hoorn, Fabio Lauria, Helena Chaytow, Kiterie M E Faller, Yu-Ting Huang, Rachel A Kline, Ilaria Signoria, Kim Morris, Thomas M Wishart, Ewout J N Groen, Gabriella Viero, Thomas H Gillingwater
Science Signaling [E], 2025, vol. 18

Long-read sequencing identifies copy-specific markers of SMN gene conversion in spinal muscular atrophy M M Zwartkruis, M G Elferink, D Gommers, I Signoria, L Blasco-Pérez, M Costa-Roger, J van der Sel, I J Renkens, J W Green, J V Kortooms, C Vermeulen, R Straver, H W M van Deutekom, J H Veldink, F Asselman, E F Tizzano, R I Wadman, W L van der Pol, G W van Haaften, E J N Groen
Genome Medicine, 2025, vol. 17

Altered mitochondrial function in fibroblast cell lines derived from disease carriers of spinal muscular atrophy Rachel James, Kiterie M.E. Faller, Ewout J.N. Groen, Brunhilde Wirth, Thomas H. Gillingwater
Communications medicine, 2024, vol. 4

Innovating spinal muscular atrophy models in the therapeutic era Ilaria Signoria, W. Ludo van der Pol, Ewout J.N. Groen
DMM Disease Models and Mechanisms, 2023, vol. 16

Robust comparison of protein levels across tissues and throughout development using standardized quantitative western blotting Yu Ting Huang, Dinja van der Hoorn, Leire M. Ledahawsky, Anna A.L. Motyl, Crispin Y. Jordan, Thomas H. Gillingwater, Ewout J.N. Groen
Journal of Visualized Experiments, 2019, vol. 2019