Profile photo Evita Wiegers

Evita Wiegers

Assistant Professor

Strategic program(s):

Biography

My mission is to bring cutting-edge metabolic imaging technologies from the research lab into clinical application. My work sits at the intersection of MR physics, neuro-oncology, and metabolism, and is driven by the conviction that understanding altered metabolic pathways in the human brain will transform how we diagnose and treat neurological disease.

I have a background in biomedical engineering (UTwente) and during my PhD I specialized in MR spectroscopy (Radboud umc, Nijmegen). Trough personal research grants (NWO-VENI and WKZonderzoeksfonds) I was able to built my own research line in which I use various x-nuclei MR spectrscopy techniques (e.g., 31P MRSI, deuterium metabolic imaging, 13C-MRS) to study metabolism in various neurological pathologies.

Research groups

Precision imaging

Research aim

Our research lines incorporate inventions of MR technology to be able to see the unseen for advancing medicine. Our clinical research focus areas are cancer, dementia, cardiovascular, stroke and MSK.

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Perinatal neuroimaging & neuromonitoring

Research aim

We use longitudinal fetal and neonatal neuroimaging and neuromonitoring to study brain development and function, model brain diseases, and improve long term outcome in high-risk infants.

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Recent publications

Reproducibility of the Determination of 13C-Labeling of Glutamate and Glutamine in the Human Brain Using selPOCE-MRS at 7 T Upon [U-13C]-Labeled Glucose Infusion Narjes Ahmadian, Sarah M Jacobs, Mark Gosselink, Wybe J M van der Kemp, Hans Hoogduin, Anastasia Coppoli, Graeme F Mason, Robin A de Graaf, Helia Norouzizadeh, Chantal Mahon, Pieter van Eijsden, Renger Tiessen, Dirk Cerneus, Corin O Miller, Inge De Lepeleire, Anthony S Basile, Dennis W J Klomp, Jeanine J Prompers, Evita C Wiegers
NMR in Biomedicine, 2025, vol. 38
Interleaved Whole Brain 23Na-MRI and 31P-MRSI Acquisitions at 7 Tesla Zahra Shams, Jiying Dai, Mark W  J Gosselink, Hans J  M Hoogduin, Wybe J  M van der Kemp, Fredy Visser, Dennis W  J Klomp, Jannie P Wijnen, Evita C Wiegers
NMR in Biomedicine, 2025, vol. 38
Development of a Double Tuned ²H/31P Whole-Body Birdcage Transmit Coil for 2H and 31P MR Applications From Head to Toe at 7 T Ayhan Gursan, Busra Kahraman-Agir, Mark Gosselink, Dimitri Welting, Martijn Froeling, Hans Hoogduin, Evita C Wiegers, Jeanine J Prompers, Dennis W J Klomp
NMR in Biomedicine, 2025, vol. 38
31P multi-echo MRSI with low B1+ dual-band refocusing RF pulses Zahra Shams, Wybe J.M. van der Kemp, Dennis W.J. Klomp, Evita C. Wiegers, Jannie P. Wijnen
NMR in Biomedicine, 2024, vol. 38
Human Brain Deuterium Metabolic Imaging at 7 T Narjes Ahmadian, Maaike M. Konig, Sigrid Otto, Kiki Tesselaar, Pieter van Eijsden, Mark Gosselink, Ayhan Gursan, Dennis W. Klomp, Jeanine J. Prompers, Evita C. Wiegers
Journal of Magnetic Resonance Imaging, 2024, vol. 61, p.1170-1178
Indirect 1H-[ 13C] MRS of the human brain at 7 T using a 13C-birdcage coil and eight transmit-receive 1H-dipole antennas with a 32-channel 1H-receive array. Sarah M Jacobs, Jeanine J Prompers, Wybe J M van der Kemp, Tijl A van der Velden, Mark Gosselink, Ettore Flavio Meliadò, Hans M Hoogduin, Graeme F Mason, Robin A de Graaf, Corin O Miller, Gerard M Bredael, Anja G van der Kolk, Cezar Alborahal, Dennis W J Klomp, Evita C Wiegers
NMR in Biomedicine, 2024, vol. 37

Fellowships & Awards

2023     Co-applicant and WP-leader research grant from the Dutch NWO Perspectief program entitled ‘CHIME: Cerebral HemodynamIcs, Metabolism and clearancE: A comprehensive, non‐invasive brain imaging approach to characterize key biological processes in dementia’

2023     Rudolf Magnus Young Talent Fellowship ‘Identification of epileptogenic brain tissue using deuterium metabolic imaging (DMI)’

2022     Co-PI research grant Dutch cancer society (KWF), entitled: ‘Early detection of brain tumour progression with amide proton transfer weighted CEST MRI’

2021     Personal research grant from the Wilhelmina Children’s Hospital Fund, entitled: ‘Exploring vascular and metabolic maturation of the preterm brain with 7T MRI’

2020     Personal research grant from the Dutch NWO Talent Programme (Veni), entitled: ‘No need to wait? Predicting brain cancer therapy response with metabolic MRI’