Eva van Rooij

Full Professor

Strategic program(s):

Contact

erooij@umcutrecht.nl

Pure profile

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Cardiac repair and regeneration

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding and stimulate our natural potential for myocardial repair.

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Molecular science & therapy in heart failure

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding of heart failure and develop new strategies for therapy.

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Recent publications

All publications

Hydrogel-Based Delivery of antimiR-195 Improves Cardiac Efficacy after Ischemic Injury Joep E.C. Eding, Marta Vigil-Garcia, Marit Vink, Charlotte J. Demkes, Danielle Versteeg, Lieneke Kooijman, Maarten H. Bakker, Maaike J.G. Schotman, Patricia Y.W. Dankers, Eva van Rooij
Advanced Therapeutics, 2024, vol. 7, p.1-13

ATF3’s shielding hand to counter ischemia-reperfusion injury in cardiac macrophages Tim Koopmans, Alejandro Cardona-Monzonís, Eva van Rooij
Nature Cardiovascular Research, 2024, vol. 3, p.15-17

Thymosin β4 and prothymosin α promote cardiac regeneration post-ischaemic injury in mice Monika M. Gladka, Anne Katrine Z. Johansen, Sebastiaan J. van Kampen, Marijn M.C. Peters, Bas Molenaar, Danielle Versteeg, Lieneke Kooijman, Lorena Zentilin, Mauro Giacca, Eva van Rooij
Cardiovascular research, 2023, vol. 119, p.802-812

Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy Cornelis J Boogerd, Grégory P A Lacraz, Ábel Vértesy, Sebastiaan J van Kampen, Ilaria Perini, Hesther de Ruiter, Danielle Versteeg, Andreas Brodehl, Petra van der Kraak, Mauro Giacca, Nicolaas de Jonge, Jan Philipp Junker, Alexander van Oudenaarden, Aryan Vink, Eva van Rooij
Cardiovascular research, 2023, vol. 119, p.477-491

Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy Hoyee Tsui, Sebastiaan Johannes van Kampen, Su Ji Han, Viviana Meraviglia, Willem B van Ham, Simona Casini, Petra van der Kraak, Aryan Vink, Xiaoke Yin, Manuel Mayr, Alexandre Bossu, Gerard A Marchal, Jantine Monshouwer-Kloots, Joep Eding, Danielle Versteeg, Hesther de Ruiter, Karel Bezstarosti, Judith Groeneweg, Sjoerd J Klaasen, Linda W van Laake, Jeroen A A Demmers, Geert J P L Kops, Christine L Mummery, Toon A B van Veen, Carol Ann Remme, Milena Bellin, Eva van Rooij
Science translational medicine, 2023, vol. 15

Gene editing innovations and their applications in cardiomyopathy research Eirini Kyriakopoulou, Thomas Monnikhof, Eva van Rooij
DMM Disease Models and Mechanisms, 2023, vol. 16