Eva van Rooij

Full Professor

Strategic program(s):

Contact

erooij@umcutrecht.nl

Pure profile

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Cardiac repair and regeneration

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding and stimulate our natural potential for myocardial repair.

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Molecular science & therapy in heart failure

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding of heart failure and develop new strategies for therapy.

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Recent publications

All publications

Maintaining the LYVE1 line through macrophage and lymphatic interplay in the regenerating neonatal heart Tim Koopmans, Eva van Rooij
Nature Cardiovascular Research, 2025, vol. 4, p.1211-1213

Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition Louk T. Timmer, Elvira den Hertog, Danielle Versteeg, Harm Post, Job A.J. Verdonschot, Jantine Monshouwer-Kloots, Eirini Kyriakopoulou, Ilaria Perini, Tim Koopmans, Petra van der Kraak, Lorena Zentilin, Stephane R.B. Heymans, Aryan Vink, Mauro Giacca, Albert J.R. Heck, Eva van Rooij
Cardiovascular research, 2025, vol. 121, p.585-600

Molecular gatekeepers of endogenous adult mammalian cardiomyocyte proliferation Tim Koopmans, Eva van Rooij
Nature Reviews Cardiology, 2025, vol. 22, p.857-882

Update on preclinical models of cancer therapy-related cardiac dysfunction Alessandra Ghigo, Pietro Ameri, Aarti Asnani, Edoardo Bertero, Rudolf A. de Boer, Dimitrios Farmakis, Arantxa González, Stephane Heymans, Borja Ibáñez, Teresa López-Fernández, Alexander R. Lyon, Piero Pollesello, Amina Rakisheva, Konstantinos Stellos, Katrin Streckfuss-Bömeke, Carlo Gabriele Tocchetti, Thomas Thum, Peter van der Meer, Eva Van Rooij, Piotr Ponikowski, Marco Metra, Giuseppe Rosano, Sophie Van Linthout
European Journal of Heart Failure, 2025, vol. 27, p.1028-1046

Engineered heart tissue patches Alain van Mil, Jasmijn Janssen, Eva van Rooij
Cell stem cell, 2025, vol. 32, p.505-507

EPAS1 induction drives myocardial degeneration in desmoplakin-cardiomyopathy Eirini Kyriakopoulou, Sebastiaan J. van Kampen, Martijn Wehrens, Su Ji Han, Hesther de Ruiter, Jantine Monshouwer-Kloots, Emma Marshall, Andreas Brodehl, Petra van der Kraak, Anneline S.J.M. te Riele, Egidius E.H.L. van Aarnhem, Linda W. van Laake, Hoyee Tsui, Cornelis J. Boogerd, Eva van Rooij
iScience, 2025, vol. 28