Profile photo Emma van Bodegraven

Emma van Bodegraven

Assistant Professor

Strategic program(s):

Biography

Emma van Bodegraven is an assistant professor at the department of Translational Neuroscience at the University Medical Center Utrecht Brain Center. Her research focuses on the interaction between brain tumors and the human brain environment, with the goal of understanding how extrinsic factors such as mechanical properties and specific brain cell types drive malignant behavior in tumors. She works in close collaboration with clinicians and uses human models, including iPSC-derived brain systems and patient-derived brain tumor cells, to investigate these complex interactions.

Emma completed her PhD at the UMC Utrecht Brain Center in 2019, after which she received a postdoctoral fellowship from Fondation ARC pour la Recherche sur le Cancer to work at the Institut Pasteur in Paris. In 2021, she returned to the UMC Utrecht Brain Center supported by a Rudolf Magnus Young Talent Fellowship and a Veni grant (ENW, NWO) to continue her postdoctoral research. Since 2023, she has held a position as assistant professor at the department of Translational Neuroscience of the UMC Utrecht Brain Center to continue her neuro-oncology research.

Recent publications

Vascularized human brain organoids: current possibilities and prospects Lois Kistemaker, Emma J van Bodegraven, Helga E de Vries, Elly M Hol
Trends in biotechnology, 2025, vol. 43, p.1275-1285
GFAP-isoforms in the nervous system Alexandra J E M de Reus, Onur Basak, Werner Dykstra, Jessy V van Asperen, Emma J van Bodegraven, Elly M Hol
Current Opinion in Cell Biology, 2024, vol. 87
Determining glioma cell invasion and proliferation in ex vivo organotypic mouse brain slices using whole-mount immunostaining and tissue clearing Jessy V van Asperen, Emma J van Bodegraven, Pierre A J T Robe, Elly M Hol
STAR protocols, 2022, vol. 3
Intermediate filaments from tissue integrity to single molecule mechanics Emma J. van Bodegraven, Sandrine Etienne-Manneville
Cells, 2021, vol. 10
New GFAP splice isoform (GFAPµ) differentially expressed in glioma translates into 21 kDa N-terminal GFAP protein Emma J. van Bodegraven, Jacqueline A. Sluijs, A. Katherine Tan, Pierre A.J.T. Robe, Elly M. Hol
FASEB Journal, 2021, vol. 35, p.1-14
Intermediate filaments against actomyosin Emma J. van Bodegraven, Sandrine Etienne-Manneville
Current Opinion in Cell Biology, 2020, vol. 66, p.79-88

Fellowships & Awards

2024, Strategic Program Cancer Boost Grant, UMC Utrecht
2021, Veni, NWO ENW
2021, Rudolf Magnus Young Talent Fellowship, UMC Utrecht Brain Center
2019, Postdoc Fellowship, Fondation ARC pour la Recherche sur le Cancer