Profile photo Emile Voest

Emile Voest

Full Professor

Biography

Emile Voest is professor of Medical Oncology, senior group leader at the Netherlands Cancer Institute, senior scientist of the Oncode Institute, and translational scientist. He is the current chair of the board of directors of Cancer Core Europe, a collaboration of 7 excellent comprehensive cancer centers. Until 2021, he served as executive medical director of the Netherlands Cancer Institute. He is also an independent, non-executive board member of Sanofi, is co-founder and serves on the non-executive board of the Hartwig Medical Foundation. He recently has co-founded Mosaic Therapeutics, devoted to developing new combinatorial treatments in a specific genomic background.

 

His academic group is devoted to bringing precision medicine to patients and is focused on large scale genomic sequencing of patients with metastatic cancer, the development of co-culture models of primary cultures of tumors (i.c. organoids) and immune cells to improve drug development and immunotherapy and to determine which treatment is best for a specific patient via computational, integrated approaches.

Recent publications

Checkpoint Blockade Combinations in Tumor Mutational Burden/Load-High Tumors Karlijn Verkerk, Soemeya F Haj Mohammad, Laurien J Zeverijn, Birgit S Geurts, Ilse A C Spiekman, Florentine A J Verbeek, Hans Timmer, Maud A van Maren, V van der Noort, Miguel Parra Martinez, Paul Roepman, Anne M L Jansen, Wendy W J de Leng, Serena Marchetti, Kim Monkhorst, Henk M W Verheul, Hans Gelderblom, Emile E Voest
Clinical cancer research : an official journal of the American Association for Cancer Research, 2025, vol. 31, p.4964-4975
The pathway alteration load is a pan-cancer determinant of outcome of targeted therapies K Verkerk, L J Zeverijn, J van de Haar, P Roepman, B S Geurts, A C Spiekman, V van der Noort, J M van Berge Henegouwen, L R Hoes, H van der Wijngaart, A M L Jansen, W W J de Leng, A J Gelderblom, H M W Verheul, E E Voest
ESMO open, 2025, vol. 10
Safety, Efficacy, and Biomarker Analysis of Crizotinib in MET-Mutated Non-Small Cell Lung Cancer-Results from the Drug Rediscovery Protocol Karlijn Verkerk, Tijmen J.W.T. van der Wel, Laurien J. Zeverijn, Birgit S. Geurts, Ilse A.C. Spiekman, Gijs F. de Wit, Paul Roepman, Anne M.L. Jansen, Vincent van der Noort, Egbert F. Smit, Ann Hoeben, Lizza E.L. Hendriks, Michel M. van den Heuvel, Berber Piet, Gerarda J.M. Herder, Sayed M.S. Hashemi, Hans Gelderblom, Henk M.W. Verheul, Emile E. Voest, Adrianus J. de Langen
Clinical Cancer Research, 2024, vol. 30, p.5323-5332
The Innate Immune Landscape of dMMR/MSI Cancers Predicts the Outcome of Nivolumab Treatment Laurien J Zeverijn, Birgit S Geurts, Thomas W Battaglia, Jade M van Berge Henegouwen, Gijs F de Wit, Louisa R Hoes, Hanneke van der Wijngaart, Vincent van der Noort, Paul Roepman, Wendy W J de Leng, Anne M L Jansen, Myriam Chalabi, Carla M L van Herpen, Lot A Devriese, Frans L G Erdkamp, Mariette Labots, Maja J A de Jonge, Emile D Kerver, Adriaan D Bins, Lindsay V M Leek, Jessica C L Notohardjo, Alfonsus J M van den Eertwegh, Lodewyk F A Wessels, Henk M W Verheul, Hans Gelderblom, Joris van de Haar, Emile E Voest
Clinical cancer research : an official journal of the American Association for Cancer Research, 2024, vol. 30, p.4339-4351
Maximizing treatment opportunities Jade M van Berge Henegouwen, Laurien J Zeverijn, Birgit S Geurts, Louisa R Hoes, Hanneke van der Wijngaart, Vincent van der Noort, Alwin D R Huitema, Filip Y F De Vos, Katrien Grünberg, Haiko J Bloemendal, Henk M W Verheul, Emile E Voest, Hans Gelderblom
Clinical cancer research : an official journal of the American Association for Cancer Research, 2024, vol. 30, p.3937-3943
Efficacy of pembrolizumab and biomarker analysis in patients with WGS-based intermediate to high tumor mutational load Birgit S Geurts, Laurien J Zeverijn, Lindsay V M Leek, Jade M van Berge Henegouwen, Louisa R Hoes, Hanneke van der Wijngaart, Vincent van der Noort, Joris van de Haar, Annemiek van Ommen-Nijhof, Marleen Kok, Paul Roepman, Anne M L Jansen, Wendy W J de Leng, Maja J A de Jonge, Ann Hoeben, Carla M L van Herpen, Hans M Westgeest, Lodewyk F A Wessels, Henk M W Verheul, Hans Gelderblom, Emile E Voest
Clinical cancer research : an official journal of the American Association for Cancer Research, 2024, vol. 30, p.3735-3746