Profile photo Edward Nieuwenhuis

Edward Nieuwenhuis

Full Professor

Strategic program(s):

Biography

Edward Nieuwenhuis, pediatrician, obtained a PhD in mucosal immunology (Prof. Blumberg, Harvard University and Prof. Heijnen, Utrecht University). He became a paediatric gastroenterologist, focusing     on the innate immunesystem in Inflammatory Bowel Disease. His work includes the development of a enterocolitis model in Zebrafish. His current research focuses on IBD, somatic stemcells, epithelial biology and genetics.

In 2009, Edward Nieuwenhuis was appointed as Chairman of the Paediatrics Division of the Wilhelmina Children’s Hospital Utrecht , The Netherlands. In 2010, he was also appointed as Chairman of the    leading program (speerpunt) Child Health of  the University Medical Center Utrecht.

During this period, the Hospital has established strong alliances with medical centers and research institutes in the Netherlands (e.g. Maxima, national center for pediatric oncology, Hubrecht institute for developmental biology & stem cell research) and abroad (e.g. Boston Children’s, The Hospital for Sick Children, Toronto, Hospital Pablo Tobon Uribe, Medellin).

His goal is to build an integrated academic Children’s Hospital which provides health care, medical training and science of excellent standards.

Recent publications

Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
iScience, 2024, vol. 27, p.1-19
The Effect of Genetic HLA Matching on Liver Transplantation Outcome Gautam Kok, Eveline F Ilcken, Roderick H J Houwen, Caroline A Lindemans, Edward E S Nieuwenhuis, Eric Spierings, Sabine A Fuchs
Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2023, vol. 4, p.1-7
Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated lymphopenia and neurodegeneration Irena J.J. Muffels, Imre F. Schene, Holger Rehmann, Maarten P.G. Massink, Maria M. van der Wal, Corinna Bauder, Martha Labeur, Natalia G. Armando, Maarten H. Lequin, Michiel L. Houben, Jaques C. Giltay, Saskia Haitjema, Albert Huisman, Fleur Vansenne, Judith Bluvstein, John Pappas, Lala V. Shailee, Yuri A. Zarate, Michal Mokry, Gijs W. van Haaften, Edward E.S. Nieuwenhuis, Damian Refojo, Femke van Wijk, Sabine A. Fuchs, Peter M. van Hasselt
American Journal of Human Genetics, 2023, vol. 110, p.146-160
Validation of a modified bedside Pediatric Early Warning System score for detection of clinical deterioration in hospitalized pediatric oncology patients Marijn Soeteman, Teus H. Kappen, Martine van Engelen, Maartje Marcelis, Ellen Kilsdonk, Marry M. van den Heuvel-Eibrink, Edward E.S. Nieuwenhuis, Wim J.E. Tissing, Marta Fiocco, Roelie M.Wösten van Asperen
Pediatric Blood and Cancer, 2023, vol. 70
An unbiased approach of molecular characterization of the endometrium Bich Ngoc Bui, Arif Ibrahim Ardisasmita, Ewart Kuijk, Signe Altmäe, Gaby Steba, Shari Mackens, Sabine Fuchs, Frank Broekmans, Edward Nieuwenhuis
Human reproduction (Oxford, England), 2023, vol. 39, p.275-281
Chemotherapy-induced intestinal injury promotes Galectin-9-driven modulation of T cell function Suze A Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E S Nieuwenhuis, Alan M Hanash, Enric Mocholi, Paul J Coffer, Caroline A Lindemans
2023

Fellowships & Awards

2022: Ammodo Science Award 2022

External positions

Raad van Toezicht - gezondheidszorg - Zorgsaam Terneuzen