Dominique de Kleijn

Full Professor

Strategic program(s):

Contact

dkleijn@umcutrecht.nl

Pure profile

Research groups

Therapy of atherosclerosis and aneurysms

Research aim

Development and validation of image guided interventions, medical devices and pharmaceutical interventions (eg anti-inflammatory/coagulation) to improve outcome of atherosclerotic disease and aneurysms

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Recent publications

All publications

Female-biased vascular smooth muscle cell gene regulatory networks predict MYH9 as a key regulator of fibrous plaque phenotype R Noah Perry, Graham Lenert, Ernest Diez Benavente, Angela Ma, Nicolas Barbera, Michal Mokry, Dominique P V de Kleijn, Menno P J de Winther, Manuel Mayr, Johan L M Björkegren, Hester M den Ruijter, Mete Civelek
2025

The IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) Petra Kleinbongard, Carlos Galán Arriola, Lina Badimon, Veronica Crisostomo, Zoltán Giricz, Mariann Gyöngyösi, Gerd Heusch, Borja Ibanez, Attila Kiss, Dominique P V de Kleijn, Bruno K Podesser, Rafael Ramírez Carracedo, Antonio Rodríguez-Sinovas, Marisol Ruiz-Meana, Francisco M Sanchez Margallo, Gemma Vilahur, José Luis Zamorano, Carlos Zaragoza, Peter Ferdinandy, Derek J Hausenloy
Basic Research in Cardiology, 2024, vol. 119, p.893–909

Plasma C-reactive protein is associated with a pro-inflammatory and adverse plaque phenotype Jordan M Kraaijenhof, Barend M Mol, Nick S Nurmohamed, Kim E Dzobo, Jeffrey Kroon, G Kees Hovingh, Michal Mokry, Gert J de Borst, Erik S G Stroes, Dominique P V de Kleijn
Atherosclerosis, 2024, vol. 396

Tobacco smoking is associated with sex- and plaque-type specific upregulation of CRLF1 in atherosclerotic lesions Tian Lan, Kaylin C.A. Palm, Luka Hoeben, Ernest Diez Benavente, R. Noah Perry, Mete Civelek, Dominique P.V. de Kleijn, Hester M. den Ruijter, Gerard Pasterkamp, Michal Mokry
Atherosclerosis, 2024, vol. 397

Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis Raisa Kraaijvanger, Montse Janssen Bonás, Jan C. Grutters, Ioanna Paspali, Marcel Veltkamp, Dominique P.V. de Kleijn, Coline H.M. van Moorsel
Respiratory research, 2024, vol. 25

Predictors of bleeding complications during catHeter-dirEcted thrombolysis for peripheral arterial occlusions (POCHET) Barend M. Mol, Maarten C. Verwer, Rob Fijnheer, Jasper Florie, Oscar A. Groot, Falco Hietbrink, Mathilde Nijkeuter, Evert Jan P.A. Vonken, Vincent van Weel, Dominique P.V. de Kleijn, Gert J. de Borst,
PLoS ONE, 2024, vol. 19