Dominique de Kleijn

Full Professor

Strategic program(s):

Contact

dkleijn@umcutrecht.nl

Pure profile

Research groups

Therapy of atherosclerosis and aneurysms

Research aim

Development and validation of image guided interventions, medical devices and pharmaceutical interventions (eg anti-inflammatory/coagulation) to improve outcome of atherosclerotic disease and aneurysms

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Recent publications

All publications

Carotid Plaques Show More Unstable Characteristics Between 2010 and 2021 After a Prior Decade of Stabilization Barend M. Mol, Tetiana Motsak, Joost K.R. Hoekstra, Gerard Pasterkamp, Gert J. de Borst, Dominique P.V. de Kleijn
Journal of the American Heart Association, 2025, vol. 14

Blood Biomarkers for the Diagnosis of Peripheral Causes of Vestibular Syndrome Vincent W Klokman, Merel J J Verhagen, Marieke S Sanders, Korné Jellema, Dominique P V de Kleijn, Kim E Jie
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2025, vol. 46, p.e359-e369

High Levels of Plasma and Plaque IsoDGR-Modified Fibronectin are Associated with Rupture Prone Plaque Characteristics in Carotid Endarterectomy Patients Barend M. Mol, Tetiana Motsak, Joost K.R. Hoekstra, Valentina Osorio Zuluaga, Saskia Rumpff-Derksen, Ioanna Paspali-Strik, Sofong Cam Ngan, Gerard Pasterkamp, Gert J. de Borst, Siu Kwan Sze, Dominique P.V. de Kleijn
European Journal of Vascular and Endovascular Surgery, 2025, vol. 70, p.287-294

Genetically determined ancestry associates with morphological and molecular carotid plaque features Nima Fahim, Tim R Sakkers, Joost Hoekstra, Dominique P V de Kleijn, Michal Mokry, Jose Verdezoto Mosquera, Gerard Pasterkamp, Hester M den Ruijter, Clint L Miller, Jessica van Setten, Sander W van der Laan
2025

Proteomic profiling reveals a higher presence of glycolytic enzymes in human atherosclerotic lesions with unfavourable histological characteristics Kaylin C A Palm, Xiaoke Yin, Ferheen Baig, Konstantinos Theofilatos, Sander W van der Laan, Gert J de Borst, Dominique P V de Kleijn, Johann Wojta, Stefan Stojkovic, Manuel Mayr, Hester M den Ruijter, Gerard Pasterkamp, Ernest Diez Benavente, Michal Mokry
Cardiovascular research, 2025, vol. 121, p.1187-1203

Interleukin-6 modifies Lipoprotein(a) and oxidized phospholipids associated cardiovascular disease risk in a secondary prevention cohort Niekbachsh Mohammadnia, Amber van Broekhoven, Willem A Bax, John W Eikelboom, Arend Mosterd, Aernoud T L Fiolet, Jan G P Tijssen, Peter L Thompson, Dominique P V de Kleijn, Sotirios Tsimikas, Jan H Cornel, Calvin Yeang, Saloua El Messaoudi
Atherosclerosis, 2025, vol. 405