Dineke Koek

Associate Professor

Strategic program(s):

Contact

hkoek@umcutrecht.nl

Pure profile

Research groups

Geriatrics and vascular disease

Research aim

Our aim is to improve diagnostic and therapeutic strategies for older patients with vascular disease, particularly patients with heart failure or vascular calcifications of the brain. We study optimalisation of pharmacotherapy and advanced therapies.

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Recent publications

All publications

The Carotid Siphon as a Pulsatility Modulator for Brain Protection Pim A de Jong, Daniel Bos, Huiberdina L Koek, Pieter T Deckers, Netanja I Harlianto, Ynte M Ruigrok, Wilko Spiering, Jaco Zwanenburg, Willem P Th M Mali
Journal of Personalized Medicine, 2025, vol. 15

GL-ICNN Wenjie Kang, Lize Jiskoot, Peter De Deyn, Geert Biessels, Huiberdina Koek, Jurgen Claassen, Huub Middelkoop, Wiesje Flier, Willemijn J. Jansen, Stefan Klein, Esther Bron
2025

Tract-specific white matter hyperintensities and neuropsychiatric syndromes Cheuk Ni Kan, Mirthe Coenen, Xin Xu, Saima Hilal, Frederik Barkhof, Thomas Benke, Peter Dal-Bianco, Charles Decarli, Marco Duering, Christian Enzinger, Lieza G. Exalto, Evan F. Fletcher, Edith Hofer, Huiberdina L. Koek, Hugo J. Kuijf, Pauline M. Maillard, Justine E.F. Moonen, Janne M. Papma, Yolande A.L. Pijnenburg, Reinhold Schmidt, Rebecca M.E. Steketee, Esther Van Den Berg, Wiesje M. Van Der Flier, Narayanaswamy Venketasubramanian, Meike W. Vernooij, Frank J. Wolters, Geert Jan Biessels, Christopher Li Hsian Chen, J. Matthijs Biesbroek, Chin Hong Tan
Journal of Neurology, Neurosurgery and Psychiatry, 2025, vol. 96, p.697-704

Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities J. Matthijs Biesbroek, Mirthe Coenen, Charles DeCarli, Evan M. Fletcher, Pauline M. Maillard, Frederik Barkhof, Josephine Barnes, Thomas Benke, Christopher P.L.H. Chen, Peter Dal-Bianco, Anna Dewenter, Marco Duering, Christian Enzinger, Michael Ewers, Lieza G. Exalto, Nicolai Franzmeier, Saima Hilal, Edith Hofer, Huiberdina L. Koek, Andrea B. Maier, Cheryl R. McCreary, Janne M. Papma, Ross W. Paterson, Yolande A.L. Pijnenburg, Anna Rubinski, Reinhold Schmidt, Jonathan M. Schott, Catherine F. Slattery, Eric E. Smith, Carole H. Sudre, Rebecca M.E. Steketee, Charlotte E. Teunissen, Esther van den Berg, Wiesje M. van der Flier, Narayanaswamy Venketasubramanian, Vikram Venkatraghavan, Meike W. Vernooij, Frank J. Wolters, Xu Xin, Hugo J. Kuijf, Geert Jan Biessels,
Alzheimer's and Dementia, 2024, vol. 20, p.2980-2989

Drug-related readmissions in older hospitalized adults Birgitta M G Snijders, Thomas G H Kempen, Carole E Aubert, Huiberdina L Koek, Olivia Dalleur, Jacques Donzé, Nicolas Rodondi, Denis O'Mahony, Ulrika Gillespie, Wilma Knol
Journal of the American Geriatrics Society, 2023, vol. 71, p.3848-3856

Inorganic phosphate exporter heterozygosity in mice leads to brain vascular calcification, microangiopathy, and microgliosis Upasana Maheshwari, José M. Mateos, Ulrike Weber-Stadlbauer, Ruiqing Ni, Virgil Tamatey, Sucheta Sridhar, Alejandro Restrepo, Pim A. de Jong, Sheng Fu Huang, Johanna Schaffenrath, Sebastian A. Stifter, Flora Szeri, Melanie Greter, Huiberdina L. Koek, Annika Keller
Brain Pathology, 2023, vol. 33, p.1-19