de Leng

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wleng@umcutrecht.nl

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Recent publications

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Clinical implications of whole genome sequencing in metastatic colorectal cancer Lidwien P Smabers, Hilde H Nienhuis, Wendy W J de Leng, Paul Roepman, Ilcan Ö A Ciftcibasi, G Emerens Wensink, Maarten A Huismans, Liselot B J Valkenburg-van Iersel, Geert A Cirkel, Elske C Gootjes, Henk M W Verheul, Frank J Jeurissen, Guus M Bol, Onno Kranenburg, Miriam Koopman, Edwin Cuppen, Jeanine M L Roodhart
Oncogene, 2025, vol. 44, p.4686-4698

Nationwide implementation and evaluation of the Tumor-First workflow for genetic testing in ovarian carcinoma Vera M Witjes, Joanne A de Hullu, Dorien M A Hermkens, Yvonne H C M Smolders, Julie E M Swillens, Sarah-Lotte Slob, Tjalling Bosse, Marian J E Mourits, Margreet G E M Ausems, Marjolijn J L Ligtenberg, Nicoline Hoogerbrugge, , Ronald Zweemer, Anne Maria Lucia Jansen, Wouter Koole, Ankie Krol-Veraar, WW de Leng
International Journal of Cancer, 2025, vol. 157, p.504-512

Clinical outcomes and genomic profiles of MAP2K1-mutated primary cutaneous melanocytic tumours Chiel F Ebbelaar, Anne M L Jansen, Leonie C M Speet, Frans Schutgens, Sietske Zoetemeyer, Anne-Marie Cleton-Jansen, Marijke R van Dijk, Gerben E Breimer, Lourens T Bloem, Wendy W J de Leng, Remco van Doorn, Karijn P M Suijkerbuijk, Anne M R Schrader, Willeke A M Blokx,
EBioMedicine, 2025, vol. 114

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics Guy Froyen, Pieter-Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W J de Leng, Anne M L Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst-Jan M Speel, Wilfred F J van IJcken, Brigitte Maes
Molecular Oncology, 2025, vol. 19, p.1797-1810

Ameloblastic Fibro-Odontoma with an FGFR1 Mutation Oumaima Aouam, Nard G Janssen, Wendy W J de Leng, Gerben E Breimer
Head and neck pathology, 2025, vol. 19

The pathway alteration load is a pan-cancer determinant of outcome of targeted therapies K Verkerk, L J Zeverijn, J van de Haar, P Roepman, B S Geurts, A C Spiekman, V van der Noort, J M van Berge Henegouwen, L R Hoes, H van der Wijngaart, A M L Jansen, W W J de Leng, A J Gelderblom, H M W Verheul, E E Voest
ESMO open, 2025, vol. 10