Profile photo Coco de Koning

Coco de Koning

Researcher/Postdoc

Strategic program(s):

Biography

My research focuses on thymus sero-immunology, since I believe that this is one of the most important yet understudied fields in immunology. My long-term research interest involves understanding thymus function in maintaining health and after thymic injury, as due to (cancer)therapies, infections, or aging. In the short-term, I specifically aim to better understand the role of the human thymic secretome in immunology and how this underevaluated thymus function affects thymopoiesis recovery after hematopoietic cell transplantation. Trained as an applied immunologist (Ph.D. dissertation, SMBWO-certification) with both laboratory and computational skills, I am a translational researcher uniquely equipped to investigate thymus immunology with a vision for clinical impact of my research. 

Recent publications

Ex vivo T-lymphopoiesis assays assisting corrective treatment choice for genetically undefined T-lymphocytopaenia Zainab M Golwala, Helena Spiridou Goncalves, Ranjita Devi Moirangthem, Grace Evans, Sabrina Lizot, Coco de Koning, Alexandrine Garrigue, Marta Martin Corredera, Juan Moises Ocampo-Godinez, Evey Howley, Susanne Kricke, Arnold Awuah, Irene Obiri-Yeboa, Rajeev Rai, Neil Sebire, Fanette Bernard, Victoria Bordon Cueto De Braem, Kaan Boztug, Theresa Cole, Andrew R Gennery, Scott Hackett, Sophie Hambleton, Mette Holm, Maaike A Kusters, Adam Klocperk, Antonio Marzollo, Nufar Marcus, Zohreh Nademi, Jana Pachlopnik Schmid, Herbert Pichler, Anna Sellmer, Pere Soler-Palacin, Maarja Soomann, Paul Torpiano, Joris van Montfrans, Stefan Nierkens, Stuart Adams, Matthew Buckland, Kimberly Gilmour, Austen Worth, Adrian J Thrasher, E Graham Davies, Isabelle André, Alexandra Y Kreins
Clinical Immunology, 2025, vol. 274
Effect of clofarabine and fludarabine exposure on outcome after pediatric allogeneic hematopoietic cell transplantation Linde Dekker, Coco de Koning, Laura Nijstad, Kim van der Elst, Rick Admiraal, Birgitta Versluijs, Jaap-Jan Boelens, Alwin Huitema, Caroline Lindemans, Stefan Nierkens
Blood Neoplasia, 2024, vol. 1
A dominant activating RAC2 variant associated with immunodeficiency and pulmonary disease B. M. Smits, P. H.C. Lelieveld, F. A. Ververs, M. Turkenburg, C. de Koning, M. van Dijk, H. L. Leavis, J. J. Boelens, C. A. Lindemans, A. C. Bloem, L. van de Corput, J. van Montfrans, S. Nierkens, M. E. van Gijn, D. P. Geerke, H. R. Waterham, L. Koenderman, M. Boes
Clinical Immunology, 2019, vol. 212