Profile photo Charlotte Onland-Moret

Charlotte Onland-Moret

Associate Professor

Strategic program(s):

Biography

I am a clinical epidemiologist with extensive experience in cohort studies, real-world data, and data-driven innovation, with a primary focus on women's health. My career began with research into the association between sex hormones and breast cancer risk. Following a two-year fellowship from the Dutch Cancer Association, I expanded my research to include hormonal-related female-specific risk factors for other cancers and cardiometabolic diseases.

Recognizing that women not only have unique risk factors and different levels of sex steroids compared to men, but also experience differences in disease diagnosis and prognosis, I have utilized large cohort studies and electronic health care data to investigate the etiology, diagnosis, and prognosis of women's health.

I serve as the co-Principal Investigator of two major population-based cohorts in Utrecht: the EPIC-NL study and the Utrecht Health Project. Additionally, I have worked as an epidemiologist and cohort manager for the YOUth cohort, contributing to its design and execution.

In my role in Utrecht, I am responsible for the development of the Health Data Space Utrecht, a regional research data infrastructure that integrates health data from the Utrecht region, including research data, electronic health records, and real-world data, for secondary use.

I am a strong advocate for team science and a multidisciplinary approach to research, collaborating closely with experts in experimental cardiology, data science, and healthcare. I am passionate about coaching and mentoring, and I take great pride in leading and developing my team.

Strategic program(s):

Contact

Research groups

Cardiovascular disease in women

Research aim

Our group's aim is to translate knowledge from experimental cardiovascular research to improve womens's cardiovascular health.

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Recent publications

Ischemia during exercise stress testing, an indication of coronary vasomotor dysfunction? Diantha J.M. Schipaanboord, Tijn P.J. Jansen, Luuk Scherpenhuijzen, Caïa Crooijmans, Aukelien C. Dimitriu-Leen, Pim van der Harst, Tim P. van de Hoef, René van Es, Hester M. den Ruijter, Peter Damman, N. Charlotte Onland-Moret, Suzette E. Elias-Smale
IJC Heart and Vasculature, 2025, vol. 56
Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans Ernest Diez Benavente, Robin J G Hartman, Tim R Sakkers, Marian Wesseling, Yannicke Sloots, Lotte Slenders, Arjan Boltjes, Barend M Mol, Gert J de Borst, Dominique P V de Kleijn, Koen H M Prange, Menno P J de Winther, Johan Kuiper, Mete Civelek, Sander W van der Laan, Steve Horvath, Charlotte Onland-Moret, Michal Mokry, Gerard Pasterkamp, Hester M den Ruijter
Arteriosclerosis, Thrombosis, and Vascular Biology, 2024, vol. 44, p.1419-1431
Worldwide trends in underweight and obesity from 1990 to 2022 Nowell H. Phelps, Rosie K. Singleton, Bin Zhou, Rachel A. Heap, Anu Mishra, James E. Bennett, Christopher J. Paciorek, Victor PF Lhoste, Rodrigo M. Carrillo-Larco, Gretchen A. Stevens, Andrea Rodriguez-Martinez, Honor Bixby, James Bentham, Mariachiara Di Cesare, Goodarz Danaei, Archie W. Rayner, Ana Barradas-Pires, Melanie J. Cowan, Stefan Savin, Leanne M. Riley, Carlos A. Aguilar-Salinas, Jennifer L. Baker, Amina Barkat, Zulfiqar A. Bhutta, Francesco Branca, Roberta B. Caixeta, Sarah Cuschieri, Farshad Farzadfar, Shubash Ganapathy, Nayu Ikeda, Violeta Iotova, Andre P. Kengne, Young Ho Khang, Avula Laxmaiah, Hsien Ho Lin, Jun Ma, Jean Claude N. Mbanya, J. Jaime Miranda, Rajendra Pradeepa, Fernando Rodríguez-Artalejo, Maroje Sorić, Maria Turley, Limin Wang, Ulrike Gehring, Nguyen D. Nguyen, N. Charlotte Onland-Moret, Erik J. Timmermans, Yvonne T. van der Schouw, WM Monique Verschuren, Indah S. Widyahening,
The Lancet, 2024, vol. 403, p.1027-1050
ANOCA patients with and without coronary vasomotor dysfunction present with limited electrocardiographic remodeling Diantha J.M. Schipaanboord, Tijn P.J. Jansen, Caïa Crooijmans, N. Charlotte Onland-Moret, Suzette E. Elias-Smale, Aukelien C. Dimitriu-Leen, Pim van der Harst, Tim P. van de Hoef, René van Es, Peter Damman, Hester M. den Ruijter
IJC Heart and Vasculature, 2024, vol. 50
General and abdominal adiposity and hypertension in eight world regions Bin Zhou, James E. Bennett, Aidan P. Wickham, Rosie K. Singleton, Anu Mishra, Rodrigo M. Carrillo-Larco, Nayu Ikeda, Lakshya Jain, Ana Barradas-Pires, Rachel A. Heap, Victor PF Lhoste, Kate E. Sheffer, Nowell H. Phelps, Archie W. Rayner, Edward W. Gregg, Mark Woodward, Gretchen A. Stevens, Maria LC Iurilli, Goodarz Danaei, Mariachiara Di Cesare, Carlos A. Aguilar-Salinas, Noor Ani Ahmad, Pascal Bovet, Zhengming Chen, Albertino Damasceno, Sarah L. Filippi, Imre Janszky, Andre P. Kengne, Young Ho Khang, Kamlesh Khunti, Avula Laxmaiah, Lee Ling Lim, Lauren Lissner, Paula Margozzini, Jean Claude N. Mbanya, Stephen T. McGarvey, Jonathan E. Shaw, Stefan Söderberg, Luis Adrián Soto-Mota, Junyang Wang, Francesco Zaccardi, Leandra Abarca-Gómez, Mohsen Abbasi-Kangevari, Ulrike Gehring, N. Charlotte Onland-Moret, Amand Floriaan Schmidt, Erik J. Timmermans, Yvonne T. van der Schouw, WM Monique Verschuren, Indah S. Widyahening,
The Lancet, 2024, vol. 404, p.851-863
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions Eileen O. Dareng, Simon G. Coetzee, Jonathan P. Tyrer, Pei Chen Peng, Will Rosenow, Stephanie Chen, Brian D. Davis, Felipe Segato Dezem, Ji Heui Seo, Robbin Nameki, Alberto L. Reyes, Katja K.H. Aben, Hoda Anton-Culver, Natalia N. Antonenkova, Gerasimos Aravantinos, Elisa V. Bandera, Laura E. Beane Freeman, Matthias W. Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, Marcus Q. Bernardini, Line Bjorge, Amanda Black, Natalia V. Bogdanova, Kelly L. Bolton, James D. Brenton, Agnieszka Budzilowska, Ralf Butzow, Hui Cai, Ian Campbell, Rikki Cannioto, Jenny Chang-Claude, Stephen J. Chanock, Kexin Chen, Georgia Chenevix-Trench, Yoke Eng Chiew, Linda S. Cook, Anna DeFazio, Joe Dennis, Jennifer A. Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Diana M. Eccles, Gabrielle Ene, Peter A. Fasching, James M. Flanagan, Renée T. Fortner, Florentia Fostira, N. Charlotte Onland-Moret, , ,
American Journal of Human Genetics, 2024, vol. 111, p.1061-1083