Profile photo Wiepke Cahn

Wiepke Cahn

Full Professor

Strategic program(s):

Biography

Prof. Wiepke Cahn has been a research psychiatrist at the University Medical Center Utrecht since 1996. In 2003 she obtained her PhD titled ‘brain morphology during the early course of schizophrenia’. She has set up various (multicenter) research projects, including GROUP. She has been chief psychiatrist for the schizophrenia program at the UMCUtrecht and project manager for the Utrecht Youth Cohort. Currently she is heading the ‘body & life’ clinic at the department of psychiatry. In 2016 she was appointed professor of psychiatry. Her research interest is the physical (ill-)health in psychiatric disorders and lifestyle psychiatry.

Wiepke Cahn has (co)authored more than 300 papers and book chapters and has been chief editor of the textbooks 'schizophrenia spectrum disorders' and 'lifestyle psychiatry' and is the author of 'focus on the families with psychiatric problems'. Her non-research-based activities consist of treating patients and their families with psychiatric and somatic co-morbidities.

Research Line

Physical health in psychiatric disorders and lifestyle psychiatry.

Key publications

1. de Boer N, Cahn W. Antipsychotic-induced weight gain: Is the weight over? New guidelines needed. Acta Psychiatr Scand. 2022 Sep;146(3):185-189

2. Burin LM, Hahn MK, da Rocha NS, van Amelsvoort T, Bartels-Velthuis AA, Bruggeman R, de Haan L, Schirmbeck F, Simons CJP, van Os J, Cahn W. Long-term treatment of antipsychotics and combined therapy with other psychotropic medications inducing weight gain in patients with non-affective psychotic disorder: Evidence from GROUP, a longitudinal study. Psychiatry Res. 2022 Aug;314:114680. 

3. de Nijs J, Pet MA; GROUP Investigators.. Metabolic syndrome in schizophrenia patients associated with poor premorbid school performance in early adolescence. Acta Psychiatr Scand. 2016 Apr;133(4):289-97.

4. Scheewe TW, Backx FJ, Takken T, Jörg F, van Strater AC, Kroes AG, Kahn RS, Cahn W. Exercise therapy improves mental and physical health in schizophrenia: a randomised controlled trial. Acta Psychiatr Scand. 2013 Jun;127(6):464-73.

5. Welie H, Derks EM, Verweij KH, de Valk HW, Kahn RS, Cahn W. The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder. Schizophr Res. 2013 Feb;143(2-3):354-7.

 

Strategic program(s):

Contact

Research groups

Innovation in psychiatry

Research aim

Innovation in Psychiatry embraces patient involvement, use different data sources and tools & methods for personalized prediction and treatment. With a holistic approach, we aim to improve the well-being of individuals with mental health problems.

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Recent publications

Prognostic predictions in psychosis Violet van Dee, Seyed M Kia, Caterina Fregosi, Wilma E Swildens, Anne Alkema, Albert Batalla, Coen van den Berg, Danko Coric, Edwin van Dellen, Lotte G Dijkstra, Arthur van den Doel, Livia S Dominicus, John Enterman, Frank L Gerritse, Marte Z van der Horst, Fedor van Houwelingen, Charlotte S Koch, Lisanne E M Koomen, Marjan Kromkamp, Michelle Lancee, Brian E Mouthaan, Diane F van Rappard, Eline J Regeer, Raymond W J Salet, Metten Somers, Jorgen Straalman, Marjolein H T de Vette, Judith Voogt, Inge Winter-van Rossum, Rene S Kahn, Wiepke Cahn, Hugo G Schnack
BMJ mental health, 2025, vol. 28
The impact of the COVID-19 pandemic on mental and psychosocial functioning, quality of life, and recovery in adults with severe mental illness Lotte van Rijn, Wilma E Swildens, Margot J Metz, Daphne Everaerd, Tinca Polderman, Wiepke Cahn, Arnt F A Schellekens, Josjan Zijlmans, Janneke R Zinkstok
European Psychiatry, 2025, vol. 68
Sex and age effects on prevalence of CYP2C19 and CYP2D6 Phenoconversion risk over time in patients with psychosis Emma Y. De Brabander, Nicole K. Leibold, Thérèse van Amelsvoort, Roos van Westrhenen, Behrooz Z. Alizadeh, Wiepke Cahn, Lieuwe de Haan, Marieke van der Pluijm, Claudia J.P. Simons, Jim van Os, Wim Veling,
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2025, vol. 138
A network approach to lifestyle behaviors and health outcomes in people with mental illness Natascha M den Bleijker, Myrthe M van Schothorst, Tessa F Blanken, Ingrid J M Hendriksen, Wiepke Cahn, Jeroen Deenik
European Psychiatry, 2025, vol. 68
Brain Markers of Resilience to Psychosis in High-Risk Individuals Guusje Collin, Joshua E Goldenberg, Xiao Chang, Zhenghan Qi, Susan Whitfield-Gabrieli, Wiepke Cahn, Jijun Wang, William S Stone, Matcheri S Keshavan, Martha E Shenton
Brain Sciences, 2025, vol. 15
Transmural collaborative care model for cardiovascular risk management and medication review in patients using antipsychotics in primary care (TACTIC) Kirsti M. Jakobs, Karlijn J. van den Brule-Barnhoorn, Jan van Lieshout, Joost G.E. Janzing, Wiepke Cahn, Wietske Kievit, Steven Teerenstra, Maria van den Muijsenbergh, Marion C.J. Biermans, Erik W.M.A. Bischoff
Contemporary Clinical Trials Communications, 2025, vol. 44

Fellowships & Awards

  • Move2 (MUVA) project 
  • Tactic project 
  • Lifestyle - A multi-modal lifestyle intervention program in routine clinical care for children with mental disorders.
  • FOCUS
  • MELIA project   
  • Psychosis Prognosis Predictor 
  • Genetic Risk and Outcome of Psychosis (GROUP project) Collaboration between AMC, UMCG en Universiteit van Maastricht and various psychiatric institutions in the Netherlands
  • Topfit project – i.s.m. met sportgeneeskunde
  • GRUMPY or Depressed – i.s.m. de sociale faculteit UU

External positions

voorzitter raad van bestuur - vergaderingen voorzitten en toezichthouden - Socialrun

Raad van Toezicht - voorzitter commissie kwaliteit & veiligheid; lid RvT - GGZBreburg