Eva Brilstra

Assistant Professor - medical

Strategic program(s):

Biography

Dr Eva Brilstra is a clinical geneticist working at the Department of Medical Genetics, University Medical Center, Utrecht. Her current research interest is in the genetics of epileptic encephalopathy.

Research line

Genetics of epileptic encephalopathy

Most recent key publications

1: Verbeek, Nienke E. MSc, MD; van der Maas, Nicoline A.T. MD; Sonsma, Anja C.M.; Ippel, Elly MD; Vermeer-de Bondt, Patricia E. MSc, MD; Hagebeuk, Eveline MD, PhD; Jansen, Floor E. MD, PhD; Geesink, Huibert H. MD; Braun, Kees P. MD, PhD; de Louw, Anton MD, PhD; Augustijn, Paul B. MD; Neuteboom, Rinze F. MD, PhD; Schieving, Jolanda H. MD; Stroink, Hans MD, PhD; Vermeulen, R. Jeroen MD, PhD; Nicolai, Joost MD, PhD; Brouwer, Oebele F. MD, PhD; van Kempen, Marjan PhD; de Kovel, Carolien G.F. PhD; Kemmeren, Jeanet M. PhD; Koeleman, Bobby P.C. PhD; Knoers, Nine V. MD, PhD; Lindhout, Dick MD, PhD; Gunning, W. Boudewijn MD,...

Strategic program(s):

Contact

e.h.brilstra@umcutrecht.nl

Pure profile

Research groups

Personalized prediction, treatment and genetics in epilepsy

Research aim

We develop personalized methods for diagnosing, treating, and predicting outcome in epilepsy. Our aim is to better control seizures, treat comorbidities, and improve quality of life with a precision medicine approach in all people with epilepsy.

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Recent publications

All publications

Somatic variant analysis of resected brain tissue in epilepsy surgery patients Maurits W.C.B. Sanders, Bobby P.C. Koeleman, Eva H. Brilstra, Floor E. Jansen, Sara Baldassari, Mathilde Chipaux, Nam Suk Sim, Ara Ko, Hoon Chul Kang, Ingmar Blümcke, Dennis Lal, Stéphanie Baulac, Jeong Ho Lee, Eleonora Aronica, Kees P.J. Braun
Epilepsia, 2024, vol. 65, p.e209-e215

N-of-1 trials in epilepsy Victoria M Defelippe, Eva H Brilstra, Willem M Otte, Helen J Cross, Finbar O'Callaghan, Valentina De Giorgis, Annapurna Poduri, Holger Lerche, Sanjay Sisodiya, Kees P J Braun, Floor E Jansen, Emilio Perucca
Epilepsia, 2024, vol. 65, p.3119-3137

Quality of life in SCN1A-related seizure disorders across the lifespan. Crista A Minderhoud, Amber Postma, Floor E Jansen, Janneke R Zinkstok, Judith S Verhoeven, Bianca Berghuis, Wim M Otte, Marian J Jongmans, Kees P J Braun, Eva H Brilstra
Brain communications, 2024, vol. 6

Genotype–phenotype associations in 1018 individuals with SCN1A-related epilepsies Declan Gallagher, Eduardo Pérez-Palma, Tobias Bruenger, Ismael Ghanty, Eva Brilstra, Berten Ceulemans, Nicole Chemaly, Iris de Lange, Christel Depienne, Renzo Guerrini, Davide Mei, Rikke S. Møller, Rima Nabbout, Brigid M. Regan, Amy L. Schneider, Ingrid E. Scheffer, An Sofie Schoonjans, Joseph D. Symonds, Sarah Weckhuysen, Sameer M. Zuberi, Dennis... Show all

Understanding neurodevelopmental trajectories and behavioral profiles in SCN1A-related epilepsy syndromes Amber Postma, Crista A. Minderhoud, Wim M. Otte, Floor E. Jansen, W. B. Gunning, Judith S. Verhoeven, Marian J. Jongmans, Janneke R. Zinkstok, Eva H. Brilstra
Epilepsy and Behavior, 2024, vol. 154

Hope, but never expect? Candice Cornelis, Aad Tibben, Eva Brilstra, Ineke Bolt, Marieke van Summeren, Nine Knoers, Annelien L Bredenoord
Molecular Genetics & Genomic Medicine, 2024, vol. 12

Fellowships & Awards

1. Fonds NutsOhra project nr 0801-64: On the relationship between childhood vaccinations and Dravet syndrome (2008)
2. Stichting Vrienden UMC on behalf of the Janivo Stichting project nr 10.053: On the relationship between childhood vaccinations and Dravet syndrome (2012)
3. Stichting Vrienden WKZ on behalf of Stichting Panta Rhei project nr...