Profile photo Bas Vastert

Bas Vastert

Associate Professor - medical

Strategic program(s):

Biography

Bas is a pediatric rheumatologist in the “EULAR center of excellence in rheumatology" Wilhelmina Children’s Hospital Utrecht. Besides being an esteemed clinician in the field of Pediatric Rheumatology, he has developed into a translational researcher, with a PhD on mechanisms of disease and therapy in severe JIA in 2013. From 2015, he has been starting a translational research group together with Jorg van Loosdregt, molecular biologist. They currently supervise 5 PhD students, 1 post-doc and 2 technicians together, within the Center of Translational Immunology in Utrecht (v Loosdregt-Vastert group). Their labgroup aims to translate cutting edge science into clinical benefit for patients and their research focusses on systemic JIA and on development of novel treatment strategies for JIA. Bas...

Research groups

Translational immunology

Research aim

It is our goal to improve the diagnosis and treatment of immune-related diseases with a focus on Juvenile Idiopathic Arthritis

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Recent publications

The 4th NextGen therapies for SJIA and MAS Grant Schulert, Sebastiaan J Vastert, Alexei A Grom
Pediatric rheumatology online journal, 2024, vol. 21
Serum proteomics reveals hemophagocytic lymphohistiocytosis-like phenotype in a subset of patients with multisystem inflammatory syndrome in children Adam J Tulling, Marloes G Holierhoek, Anja M Jansen-Hoogendijk, Levi Hoste, Filomeen Haerynck, Simon J Tavernier, Rianne Oostenbrink, Corinne M P Buysse, Michiel A G E Bannier, Jolita Bekhof, Mijke Breukels, Sanne C Hammer, Monique A M Jacobs, Arvid W A Kamps, Jan W van der Linden, Ankie Lebon,...
Validation of the EQ-5D-Y-5L parent-proxy version among children with juvenile idiopathic arthritis Arto Ohinmaa, Jiabi Wen, Gillian R. Currie, Susanne M. Benseler, Joost F. Swart, Sebastiaan J. Vastert, Rae S.M. Yeung, Deborah A. Marshall
Quality of Life Research, 2024, vol. 33, p.2677-2691
N6-Methyladenosine Promotes TNF mRNA Degradation In CD4+ T Lymphocytes Ellen C N van Vroonhoven, Lucas W Picavet, Rianne C Scholman, Lyanne J P M Sijbers, Corlinda R E Kievit, Noortje A M van den Dungen, Michal Mokry, Anouk Evers, Robert J Lebbink, Enric Mocholi, Paul J Coffer, Jorg J A Calis, Sebastiaan J Vastert, Jorg van Loosdregt
...
Get Spliced Maurice J.H. van Haaren, Levina Bertina Steller, Sebastiaan J. Vastert, Jorg J.A. Calis, Jorg van Loosdregt
International Journal of Molecular Sciences, 2024, vol. 25
Humoral and cellular immunogenicity, effectiveness and safety of COVID-19 mRNA vaccination in patients with pediatric rheumatic diseases Mohamad Hamad Saied, Joeri W van Straalen, Sytze de Roock, Frans M Verduyn Lunel, Jelle de Wit, Lia G H de Rond, Erika Van Nieuwenhove, Bas J Vastert, Joris M van Montfrans, Annet van Royen-Kerkhof, Gerrie C J de Joode-Smink, Joost F Swart, Nico M Wulffraat, Marc H A...

Fellowships & Awards

- 2007: Young investigator Meeting, Pediatric rheumatology European Society: Award for best basic abstract .

- 2014: Wilhelmina Research Fund (co-applicant), € 150 000 : Dissecting the complex role of S100-proteins in systemic juvenile idiopathic arthritis.

- 2015: ZonMW Rational Pharmacotherapy grant, € 340...