Profile photo Bas Raaymakers

Bas Raaymakers

Full Professor

Strategic program(s):

Biography

Bas Raaymakers is working to improve cancer therapy by investigating, as well as developing, new high precision radiotherapy.
Together with prof Jan Lagendijk but also with industrial partners Elekta and Philips he designed and built a hybrid MRI accelerator to facilitate high precision, soft-tissue based image guidance for radiotherapy. This enables better radiotherapy via dose escalation while decreasing toxicity.
At the same time, the translation of this new technology to the clinic is pursued. For instance fast, on-line treatment planning, so that the patient is treated based on the latest state of the anatomy. This improves the current radiotherapy practice and at the same time is a requirement for smooth clinical introduction of the MRI accelerator.
Clinical work flow and procedures for different tumour sites are under investigation. Two major categories can be distinguished: The first is improving the existing radiotherapy patient treatments, so better conform the dose distribution to the tumour shape to minimise harm to the surroundings. The second is enabling radiotherapy as an alternative for surgery for patients currently not eligible for radiotherapy, e.g. highly mobile tumours in the kidney. The motion is too large to safely administer dose with conventional radiotherapy technology, with the on-line MRI guidance the motion uncertainty can be mitigated and radiation can be safely administered, offering a completely non-invasive treatment.

Strategic program(s):

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Research groups

Experimental clinical physics radiotherapy

Research aim

The experimental clinical physics group is developing, exploring and clinically evaluating new adaptive workflows for MRI and X-ray guided radiotherapy, e.g. for the hybrid 1.5T MRI linac which has been developed in UMC Utrecht and is currently on the market via Elekta as the Unity system.

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Recent publications

Clinical validation of a high-definition mid-position magnetic resonance imaging approach for lung radiotherapy planning Katrinus Keijnemans, Astrid L H M W van Lier, Pim T S Borman, Hilâl Tekatli, Jacquelien Pomp, Romy E van Weelderen, Bas W Raaymakers, Martin F Fast
Medical physics, 2026, vol. 53
Motion mitigation in positron-emission tomography guided radiotherapy delivered on a magnetic resonance imaging-linear accelerator Albert J. Everard, Rodrigo José Santo, Pim T.S. Borman, Prescilla Uijtewaal, Martin F. Fast, Hugo W.A.M. de Jong, Cornelis A.T. van den Berg, Bas W. Raaymakers, Casper Beijst
Physics and Imaging in Radiation Oncology, 2026, vol. 39
The first experimental implementation of real-time dose-guided MLC tracking using an MRI-linac Emily A. Hewson, Pim T.S. Borman, Bas W. Raaymakers, Paul J. Keall, Martin F. Fast
Radiotherapy and Oncology, 2026, vol. 219
X-ray beam quality checks of a magnetic resonance-guided linear accelerator with its on-board megavoltage imager Guido C. Hilgers, Simon J. Woodings, Thomas A. Foppen, Jochem W.H. Wolthaus, Bram van Asselen, André W. Minken, Bas W. Raaymakers
Physics and Imaging in Radiation Oncology, 2026, vol. 37
A Bayesian framework for the detection of physiological pulmonary ventilation changes Paris Tzitzimpasis, Bas W. Raaymakers, Mario Ries, Cornel Zachiu
Physics in medicine and biology, 2026, vol. 71
Real-time dose reconstruction and dose coverage forecasting using the magnetic resonance linear accelerator Peter R.S. Stijnman, Pim T.S. Borman, Stijn Oolbekkink, Cornel Zachiu, Martin F. Fast, Bas W. Raaymakers
Physics and Imaging in Radiation Oncology, 2026, vol. 37

Fellowships & Awards

VENI grant in 2003, Technical feasibility of the MRI accelerator

External positions

Member of International Advisory Committee of Physics in Medicine and Biology - adviseren over geschiktheid van artikelen voor PMB - IOP