Anneline te Riele

Assistant Professor - medical

Strategic program(s):

Contact

ariele3@umcutrecht.nl

Pure profile

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Recent publications

All publications

EPAS1 induction drives myocardial degeneration in desmoplakin-cardiomyopathy Eirini Kyriakopoulou, Sebastiaan J. van Kampen, Martijn Wehrens, Su Ji Han, Hesther de Ruiter, Jantine Monshouwer-Kloots, Emma Marshall, Andreas Brodehl, Petra van der Kraak, Anneline S.J.M. te Riele, Egidius E.H.L. van Aarnhem, Linda W. van Laake, Hoyee Tsui, Cornelis J. Boogerd, Eva van Rooij
iScience, 2025, vol. 28

Family Screening in Patients With Dilated and Arrhythmogenic Cardiomyopathy Sophie L.V.M. Stroeks, Steven Muller, Nina J. Beelen, Max F.G.H.M. Venner, Annette F. Baas, Vanessa P.M. van Empel, Ingrid P.C. Krapels, Mark R. Hazebroek, Anneline S.J.M. te Riele, Job A.J. Verdonschot
Circulation: Genomic and Precision Medicine, 2025, vol. 18

Recreational and Occupational Physical Activity and Risk of Adverse Events in Truncating MYBPC3 Founder Variant Carriers. Fahima Hassanzada, Mark Jansen, Freyja H M van Lint, Laurens P Bosman, Amand F Schmidt, Dennis Dooijes, Danny van de Sande, Bristi Miah, Saskia N van der Crabben, Arthur A M Wilde, Ronald H Lekanne Deprez, Rudolf A de Boer, Imke Christiaans, Jan D H Jongbloed, Harald T Jorstad, Folkert W Asselbergs, J Peter van Tintelen, Annette F Baas, Anneline S J M Te Riele
Circulation. Genomic and precision medicine, 2024, vol. 17

Performance of ARVC Risk Calculators in (Likely) Pathogenic Plakophilin-2 Variant Carriers Without Definite ARVC Diagnosis Steven A. Muller, Babken Asatryan, Brittney Murray, Crystal Tichnell, Moniek G.P.J. Cox, Ahmad S. Amin, Sing Chien Yap, Alessio Gasperetti, Richard T. Carrick, Julia Cadrin-Tourigny, Marish I.F.J. Oerlemans, Hugh Calkins, J. Peter Van Tintelen, Cynthia A. James, Anneline S.J.M. Te Riele
Circulation: Arrhythmia and Electrophysiology, 2024, vol. 18

Diversity of heart failure phenotypes in transthyretin amyloid cardiomyopathy. More than just heart failure with preserved ejection fraction Anouk Achten, Steven A Muller, Sandra Sanders-van Wijk, Manon G van der Meer, Pim van der Harst, Peter van Tintelen, Anneline Sjm Te Riele, Vanessa van Empel, Marish Ifj Oerlemans, Christian Knackstedt
Annals of Medicine, 2024, vol. 56

Clinical features and outcomes in carriers of pathogenic desmoplakin variants Alessio Gasperetti, Richard T Carrick, Alexandros Protonotarios, Brittney Murray, Mikael Laredo, Iris van der Schaaf, Ronald H Lekanne, Petros Syrris, Douglas Cannie, Crystal Tichnell, Chiara Cappelletto, Marta Gigli, Kristen Medo, Ardan M Saguner, Firat Duru, Nisha A Gilotra, Stefan Zimmerman, Robyn Hylind, Dominic J Abrams, Neal K Lakdawala, Julia Cadrin-Tourigny, Mattia Targetti, Iacopo Olivotto, Maddalena Graziosi, Moniek Cox, Elena Biagini, Philippe Charron, Michela Casella, Claudio Tondo, Momina Yazdani, James S Ware, Sanjay K Prasad, Leonardo Calò, Eric D Smith, Adam S Helms, Sophie Hespe, Jodie Ingles, Harikrishna Tandri, Flavie Ader, Giovanni Peretto, Stacey Peters, Ari Horton, Jess Yao, Sven Dittmann, Eric Schulze-Bahr, Maria Qureshi, Katelyn Young, Eric D Carruth, Chris Haggerty, Victoria N Parikh, Matthew Taylor, Luisa Mestroni, Arthur Wilde, Gianfranco Sinagra, Marco Merlo, Estelle Gandjbakhch, J Peter van Tintelen, Anneline S J M Te Riele, Perry M Elliott, Hugh Calkins, Cynthia A James
European heart journal, 2024, vol. 46, p.362-376

Fellowships & Awards

Grants:

ZonMW Off Road: "Focus on Energy Metabolism in Arrhythmogenic Cardiomyopathy" (FUEL-Cardiomyopathy) (2023-2024)
Dutch CardioVascular Alliance Mini Consortium Grant (2024-2027; role: Principal Investigator)
HORIZON Cardiogenomics Pathfinder "Cardiogenomics meets artificial intelligence: a step forward in arrhythmogenic cardiomyopathy diagnosis and treatment" (2023-2027; role: WP leader)
CVON: An Original Netherlands Cardiovascular Research Initiative - Predict Sudden Cardiac Death (PREDICT) Young Talent Program (2018)
Nederlandse Hartstichting (Dutch Heart Foundation) - Dr. E. Dekker Stipend Physician in Specialty Training (2016-2021)
UMC Utrecht - Fellowship Clinical Research Talent (2016-2019)
CVON: An Original Netherlands Cardiovascular Research Initiative - Early Detection of Disease in Cardiomyopathy Mutation Carriers (eDETECT, role: WP leader)(2016-2022)
Heart Rhythm Society - Postdoctoral Fellowship in Honor of Mark Josephson and Hein Wellens (2014-2015)
American Heart Association - Predoctoral Fellowship (not accepted due to conflicting funding sources)(2014)
UMC Utrecht - Alexandre Suerman Stipend (2013-2015)
Nederlandse Hartstichting (Dutch Heart Foundation) - Dr. E. Dekker Student Grant (2012)

Awards:

Fellow of the European Society of Cardiology (2024)
Research Career Development Program, UMC Utrecht (2022-2023)
Best original manuscript published in Cardiovascular Research (2017)
Girard de Mielet van Coehoorn Stichting - Thesis Award (2016)
WCN (working group of cardiovascular research The Netherlands) - Best Cardiovascular Publication from The Netherlands 2014-2015 (2015)
European Cardiac Arrhythmia Society - Best Abstract Award (2014 and 2015)
Northwestern University Cardiovascular Young Investigators' Forum - Finalist (2014 and 2015; awarded second prize in 2015)
Johns Hopkins Cardiovascular Research - Stanley L. Blumenthal Award for Best Presentation (2015)
Lindau Nobel Laureate Meeting - Young Researcher (Nomination by Royal Netherlands Academy of Arts and Sciences)(2015)
NVVC (Netherlands Society of Cardiology) - Best Presentation in Cardiomyopathy Session (3/2015)
UMC Utrecht - Best Oral Presentation Research Colloquium Cardiology (2013-2014)

Other experience and professional memberships

Active member of Expert Center Alliance in Inherited Heart Diseases: "European Reference Network GUARD-Heart"
Principal Investigator UCC-UNRAVEL biobank (www.unravelrdp.nl; 2022-present)
Co-director Netherlands ACM registry (www.acmregistry.nl; 2018-present)
Member of working group Cardiogenetics Netherlands (2018-present)
Early career editorial board of the Journal of the American Heart Association (2021-2022)
Board member of Young@Heart, representing the interests of young cardiovascular researchers in the Netherlands (2020-2022)
Regular teaching activities at Curriculum Geneeskunde University Utrecht and UMC Utrecht Academy (2016-present)