Anneline te Riele

Assistant Professor - medical

Strategic program(s):

Contact

ariele3@umcutrecht.nl

Pure profile

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Recent publications

All publications

Setting the stage for cardiomyopathy gene editing trials C Nina van der Wilt, Rogier J A Veltrop, Maaike H Janssens, Iara Bakker, Francesca Stillitano, Joost P G Sluijter, Linda W van Laake, Jolanda van der Velden, Eric Villard, Judith Montag, Chris Denning, J Peter van Tintelen, Anneline S J M Te Riele, Pim van der Harst, Leon J Schurgers, Frank G van Steenbeek, Magdalena Harakalova
European heart journal open, 2026, vol. 6

Body surface potential mapping of ventricular depolarization and repolarization in phospholamban and plakophilin-2 cardiomyopathy Iris van der Schaaf, Manon Kloosterman, Machteld J. Boonstra, Rob W. Roudijk, Anneline S.J.M. te Riele, Peter M. van Dam, Peter Loh
Heart Rhythm O2, 2025, vol. 7, p.130-142

High Burden of Ventricular Arrhythmias and Cardiac Conduction Disease in Pediatric Patients with Pathogenic Desmin (DES) Variants Babken Asatryan, Marina Rieder, Brittney Murray, Steven A Muller, Crystal Tichnell, Alessio Gasperetti, Richard T Carrick, Emily Joseph, Doris G Leung, Anneline S J M Te Riele, Stefan L Zimmerman, Hugh Calkins, Cynthia A James, Caridad M De La Uz, Andreas S Barth
2025

Impact of genotype-phenotype associations on prognosis in dilated cardiomyopathy Sophie L V M Stroeks, Ping Wang, Marco Merlo, Steven Muller, Alessia Paldino, Nerea Mora-Ayestaran, Max Jason, Matteo Dal Ferro, Carola Pio Loca, Fernando Dominguez, Esther Gonzalez-Lopez, Arthur van den Wijngaard, Max F G H M Venner, Maurits Sikking, Michiel Minten, Bastien Nihant, Nina Beelen, Sharon Graw, Kristen Medo, Bart de Koning, Matthew Taylor, J Peter van Tintelen, Luisa Mestroni, Gianfranco Sinagra, Anneline S J M Te Riele, Pablo Garcia-Pavia, Stephane Heymans, Job A J Verdonschot
European Journal of Heart Failure, 2025, vol. 27, p.3205-3218

CineECG detects abnormal electrical activity in the 12-lead ECG of preclinical plakophilin-2 variant carriers Iris van der Schaaf, Manon Kloosterman, Anton P.M. Gorgels, Anneline S.J.M. te Riele, Peter M. van Dam, Peter Loh
Heart Rhythm O2, 2025, vol. 6, p.1786-1795

Diagnostic Criteria and Disease Staging for Desmoplakin Cardiomyopathy Eric Smith, Alessio Gasperetti, Richard T Carrick, Alexandros Protonotarios, Petros Syrris, Barbara Bauce, Kalliopi Pilichou, Brittney Murray, Crystal Tichnell, Cristina Basso, Paul Anders Sletten Olsen, Chiara Cappelletto, Victoria N Parikh, Liang Chen, Stacey Peters, Antonella Mancinelli, Anna Maria Iorio, Roberta Scotto, Julia Cadrin-Tourigny, Nisha A Gilotra, Manuela Iseppi, Giovanni Peretto, Marco Schiavone, Mark Abela, Daniela Vargas, Cinzia Crescenzi, Leonardo Calò, James Ware, Lia Crotti, Michele Ciabatti, Michela Casella, Alexandra Apostu, Ruxandra Jurcut, Claudia Raineri, Filippo Angelini, Carlos Fernández-Sellers, Esther Zorio, Sing-Chien Yap, Moniek G Cox, Arman Salavati, Anneline Te Riele, Arthur Wilde, Ahmad S Amin, Peter van Tintelen, Ardan M Saguner, Firat Duru, Dominic Abrams, Marina Cerrone, Maddalena Graziosi, Elena Biagini, Juan Ramon Gimeno, Estelle Gandjbakhch, Neal Lakdawala, Maurizio Pieroni, Marco Merlo, Gianfranco Sinagra, Kristina Haugaa, Elena Arbelo, Perry M Elliott, Matthew Taylor, Luisa Mestroni, Hugh Calkins, Cynthia A James, Adam S Helms
2025

Fellowships & Awards

Grants:

ZonMW Off Road: "Focus on Energy Metabolism in Arrhythmogenic Cardiomyopathy" (FUEL-Cardiomyopathy) (2023-2024)
Dutch CardioVascular Alliance Mini Consortium Grant (2024-2027; role: Principal Investigator)
HORIZON Cardiogenomics Pathfinder "Cardiogenomics meets artificial intelligence: a step forward in arrhythmogenic cardiomyopathy diagnosis and treatment" (2023-2027; role: WP leader)
CVON: An Original Netherlands Cardiovascular Research Initiative - Predict Sudden Cardiac Death (PREDICT) Young Talent Program (2018)
Nederlandse Hartstichting (Dutch Heart Foundation) - Dr. E. Dekker Stipend Physician in Specialty Training (2016-2021)
UMC Utrecht - Fellowship Clinical Research Talent (2016-2019)
CVON: An Original Netherlands Cardiovascular Research Initiative - Early Detection of Disease in Cardiomyopathy Mutation Carriers (eDETECT, role: WP leader)(2016-2022)
Heart Rhythm Society - Postdoctoral Fellowship in Honor of Mark Josephson and Hein Wellens (2014-2015)
American Heart Association - Predoctoral Fellowship (not accepted due to conflicting funding sources)(2014)
UMC Utrecht - Alexandre Suerman Stipend (2013-2015)
Nederlandse Hartstichting (Dutch Heart Foundation) - Dr. E. Dekker Student Grant (2012)

Awards:

Fellow of the European Society of Cardiology (2024)
Research Career Development Program, UMC Utrecht (2022-2023)
Best original manuscript published in Cardiovascular Research (2017)
Girard de Mielet van Coehoorn Stichting - Thesis Award (2016)
WCN (working group of cardiovascular research The Netherlands) - Best Cardiovascular Publication from The Netherlands 2014-2015 (2015)
European Cardiac Arrhythmia Society - Best Abstract Award (2014 and 2015)
Northwestern University Cardiovascular Young Investigators' Forum - Finalist (2014 and 2015; awarded second prize in 2015)
Johns Hopkins Cardiovascular Research - Stanley L. Blumenthal Award for Best Presentation (2015)
Lindau Nobel Laureate Meeting - Young Researcher (Nomination by Royal Netherlands Academy of Arts and Sciences)(2015)
NVVC (Netherlands Society of Cardiology) - Best Presentation in Cardiomyopathy Session (3/2015)
UMC Utrecht - Best Oral Presentation Research Colloquium Cardiology (2013-2014)

Other experience and professional memberships

Active member of Expert Center Alliance in Inherited Heart Diseases: "European Reference Network GUARD-Heart"
Principal Investigator UCC-UNRAVEL biobank (www.unravelrdp.nl; 2022-present)
Co-director Netherlands ACM registry (www.acmregistry.nl; 2018-present)
Member of working group Cardiogenetics Netherlands (2018-present)
Early career editorial board of the Journal of the American Heart Association (2021-2022)
Board member of Young@Heart, representing the interests of young cardiovascular researchers in the Netherlands (2020-2022)
Regular teaching activities at Curriculum Geneeskunde University Utrecht and UMC Utrecht Academy (2016-present)