Profile photo Anne de Hond

Anne de Hond

Assistant Professor

Biography

Anne de Hond is an assistant professor in the data science program of the Julius Center at the UMC Utrecht. She completed a master's degree in econometrics and worked as a data scientist and researcher in the AI team at Leiden UMC’s CAIRELab during her PhD research. Her research focuses on the responsible development, validation, and implementation of AI algorithms in healthcare. Amongst other applications, she developed AI models to predict hospital admission at the emergency department and depression risk in oncology patients. She also collaborated with various AI startups to investigate the practical implementation of their software. Her current research focusses on validation methods for clinical AI, including large language models like ChatGPT, as well as explainability and fairness of AI algorithms.

Recent publications

Machine learning-based prediction of short-and long-term mortality for shared decision-making in older hip fracture patients Hidde Dijkstra, Cathleen S. Parsons, Hanne Eva VAN BREMEN, Hanna C. Willems, Anne A.H. DE HOND, Barbara C. VAN MUNSTER, Job N. Doornberg, Jacobien H.F. Oosterhoff
Acta Orthopaedica, 2025, vol. 96, p.521-528
International partnership for governing generative artificial intelligence models in medicine Jasmine Chiat Ling Ong, Yilin Ning, Gary S. Collins, Danielle S. Bitterman, Ashley N. Beecy, Robert T. Chang, Alastair K. Denniston, Oscar Freyer, Stephen Gilbert, Anne de Hond, Artuur M. Leeuwenberg, Liang Zhao, John C.W. Lim, Mingxuan Liu, Xiaoxuan Liu, Christopher A. Longhurst, Yian Ma, Yue Qiu, Rupa Sarkar, Bin Sheng, Kuldev Singh, Iris Siu Kwan Tan, Yih Chung Tham, Arun J. Thirunavukarasu, Daniel Shu Wei Ting, Silke Vogel, Rui Zhang, Jianfei Zhao, Wendy W. Chapman, Nigam H. Shah, Karel G.M. Moons, Tien Yin Wong, Nan Liu
Nature medicine, 2025, vol. 31, p.2836–2839
Is frailty incremental to the 4C Mortality model for mortality risk prediction in hospitalized older individuals with COVID-19 disease? Anum Zahra, Bas F M van Raaij, Maarten van Smeden, Rishi K Gupta, Jacobijn Gussekloo, Kim Luijken, Karel G M Moons, Simon P Mooijaart, Raymond Noordam, Anne A H de Hond,
Journal of Clinical Epidemiology, 2025, vol. 185
When, where, who, what, and why? The five Ws of workflow analysis for implementing an AI decision support tool at the intensive care Anne A.H. de Hond, Suzanne Vosslamber, Sanne Lange, Friso Engel, Mette Lindhout, Puck Noorlag, Ewout W. Steyerberg, Giovanni Cinà, M. Sesmu Arbous
Human Factors in Healthcare, 2025, vol. 7
Charlson comorbidity index has no incremental value for mortality risk prediction in nursing home residents with COVID-19 disease Anum Zahra, Maarten van Smeden, Petra J.M. Elders, Jan Festen, Jacobijn Gussekloo, Karlijn J. Joling, Anouk van Loon, Kim Luijken, René J.F. Melis, Simon P. Mooijaart, Karel G.M. Moons, Geeske Peeters, Harmke A. Polinder-Bos, Fenne Wouters, Anne de Hond
BMC Geriatrics, 2025, vol. 25
The Harms of Class Imbalance Corrections for Machine Learning Based Prediction Models Alex Carriero, Kim Luijken, Anne de Hond, Karel G.M. Moons, Ben van Calster, Maarten van Smeden
Statistics in Medicine, 2025, vol. 44