Aniek Janssen

Associate Professor

Strategic program(s):

Contact

ajansse2@umcutrecht.nl

Pure profile

Research groups

Chromatin dynamics and genome instability

Research aim

We aim to understand how chromatin dynamics contributes to the maintenance of genome stability and how chromatin defects can contribute to genome instability and cancer development in the long run.

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Recent publications

All publications

Polymorphic transposable elements contribute to variation in recombination landscapes Yuheng Huang, Zita Y Gao, Kayla Ly, Leila Lin, Jan-Paul Lambooij, Elizabeth G King, Aniek Janssen, Kevin H-C Wei, Yuh Chwen G Lee
Proceedings of the National Academy of Sciences of the United States of America, 2025, vol. 122

Improved GVHD-free and relapse-free survival after ex vivo αβTCR and CD19 depleted allogeneic HSCT compared to T cell replete HSCT A H G Stuut, C Nijssen, L van der Wagen, A van Rhenen, L G M Daenen, A Janssen, F A Verheij, I Brinkman, F M Verduyn Lunel, H Koene, R Fijnheer, H J Prins, K Westinga, J Drylewicz, J Kuball, M A de Witte
Bone Marrow Transplantation, 2025, vol. 60, p.673-681

DNA double-strand break movement in heterochromatin depends on the histone acetyltransferase dGcn5 Apfrida Kendek, Arianna Sandron, Jan Paul Lambooij, Serafin U. Colmenares, Severina M. Pociunaite, Iris Gooijers, Lars de Groot, Gary H. Karpen, Aniek Janssen
Nucleic acids research, 2024, vol. 52, p.11753-11767

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair Marieke R. Wensveen, Aditya A. Dixit, Robin van Schendel, Apfrida Kendek, Jan Paul Lambooij, Marcel Tijsterman, Serafin U. Colmenares, Aniek Janssen
Nature Communications, 2024, vol. 15

The impact of chromatin on double-strand break repair Marit A E van Bueren, Aniek Janssen
DNA repair, 2024, vol. 133

The Sound of Silence: How Silenced Chromatin Orchestrates the Repair of Double-Strand Breaks Apfrida Kendek, Marieke R. Wensveen, Aniek Janssen
Genes, 2021, vol. 12