Profile photo André Knulst

André Knulst

Full Professor

Strategic program(s):

Biography

Prof. dr. André C. Knulst is dermatologist and immunologist at the Department of Dermatology/Allergology of the UMC Utrecht. He heads the outpatient department of Allergology and  has a longstanding experience in diagnosis and treatment of patients with allergies, urticaria and angio-edema, with a particular interest in food allergy, urticaria and angio-edema. The Dept. of Dermatology/Allergology is a centre of expertise for eczema, food allergy and urticaria/angio-edema. Prof. Knulst is involved in the training of dermatologists, otolaryngologists, pediatric allergists, and clinical immunologists/internist-allergologists.

He also heads the allergy research. Within the UMC Utrecht there is a close collaboration with the department of Children’s Pulmonology and Allergology and the Center of Translational Immunology of the UMC Utrecht. His research focus is on patient profiling and improvement of food allergy diagnosis a.o. using component resolved diagnostics. He participated in many multicenter studies a.o. the EU sponsored SAFE, CREATE and Europrevall projects. Another research area of particular interest is the development of novel therapeutic options for food allergy. He was involved in the VIPES study on the efficacy and safety of epicutaneously administered peanut and the FAST study on the efficacy of subcutaneous immunotherapy using a hypoallergenic cod fish parvalbumin.

 

Research groups

Acute inflammation - Food allergy

Research aim

We aim to improve allergy diagnosis and increase quality of life to reduce healthcare costs by developing predictive diagnostic tools, get insight into food allergy mechanisms and increase understanding and awareness of allergic risks of (new) foods.

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Acute inflammation – Chronic urticaria and idiopathic angio-edema

Research aim

To improve diagnostics and treatment for patients with chronic urticaria, increase quality of life and reduce healthcare costs. To clarify pathomechanism of CU as well as response to different therapeutic strategies and its predictors.

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Recent publications

Real-Life Clinical Experience With SQ Grass, Tree, Ragweed, and House Dust Mite Sublingual Immunotherapy Tablets Oliver Pfaar, Christer Janson, Andreas Horn, André C. Knulst, Pascal Demoly
Allergy: European Journal of Allergy and Clinical Immunology, 2025, vol. 80, p.3290-3301
Exploring Siglecs J S H Schaapherder, K C M Verhoeckx, A M Ehlers, E F Knol, A C Knulst, L A P M Meulenbroek
Clinical and Experimental Allergy, 2025, vol. 55, p.889-900
House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice Žana Tempels-Pavlica, Mark C J Aarts, Paco M J Welsing, Akke-Nynke van der Meer, Leonard P van der Zwan, Elena Uss, André C Knulst
Frontiers in allergy, 2024, vol. 5
Desensitisatie met geneesmiddelen: behandeling van geneesmiddelenovergevoeligheid Rimoon Hurmuz, Astrid Versluis, L Kronemeijer, Inge Baas, Jan Dekker, André C. Knulst, H Rockmann-Helmbach
Nederlands Tijdschrift voor Dermatologie en Venereologie, 2023, vol. 33, p.14-16
Component Ana o 3 versus extract for cashew nut allergy Emily J.J. Kallen, Juliette F. Bollemeijer, André C. Knulst, Anna M. Ehlers, Paco M.J. Welsing, Ronald van Ree, Thuy My Le
Clinical and Experimental Allergy, 2023, vol. 53, p.880-882
A European-Japanese study on peach allergy E. J.J. Kallen, A. Revers, M. Fernández-Rivas, R. Asero, B. Ballmer-Weber, L. Barreales, S. Belohlavkova, F. de Blay, M. Clausen, R. Dubakiene, M. Ebisawa, C. Fernández-Perez, P. Fritsche, Y. Fukutomi, D. Gislason, K. Hoffmann-Sommergruber, M. Jedrzejczak-Czechowicz, A. C. Knulst, M. L. Kowalski, T. Kralimarkova, J. Lidholm, C. Metzler, E. N.C. Mills, N. G. Papadopoulos, T. A. Popov, A. Purohit, I. Reig, S. L. Seneviratne, A. Sinaniotis, M. Takei, S. A. Versteeg, A. E. Vassilopoulou, S. Vieths, P. M.J. Welsing, A. H. Zwinderman, T. M. Le, R. Van Ree
Allergy: European Journal of Allergy and Clinical Immunology, 2023, vol. 78, p.2497-2509

External positions

Geven nascholing en presentat, advisory boards, DSMB, gezondheidsraad, richtlijn cie ed, zie bijlage - als expert hiervoor gevraagd - UMC Utrecht