Alwin Huitema

Full Professor

Strategic program(s):

Contact

ahuitem8@umcutrecht.nl

Pure profile

Research groups

Clinical pharmacy research

Research aim

The mission of the clinical pharmacy program is to explain, predict and improve patients’ response to pharmacotherapeutic treatment using clinical pharmacological and clinical pharmacoepidemiological approaches.

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Recent publications

All publications

LC-MS/MS method development and validation for novel targeted anticancer therapies adagrasib, capmatinib, ensartinib, entrectinib, larotrectinib, lorlatinib, pralsetinib, selpercatinib and sotorasib Marinda Meertens, L Daniëlle de Jong, Niels de Vries, Hilde Rosing, Jos H Beijnen, Alwin D R Huitema
Journal of Pharmaceutical and Biomedical Analysis, 2025, vol. 266

Validated LC-MS/MS Method for Quantifying the Antiparasitic Nitroimidazole DNDI-0690 in Preclinical Target Site PK/PD Studies Wietse M Schouten, Katrien van Bocxlaer, Hilde Rosing, Alwin D R Huitema, Jos H Beijnen, Jadel M Kratz, Charles E Mowbray, Thomas P C Dorlo
Biomedical Chromatography, 2025, vol. 39

Improved survival with model-based dosing of antithymocyte globulin in pediatric hematopoietic cell transplantation Rick Admiraal, Stefan Nierkens, Marc B. Bierings, Mirjam E. Belderbos, Alwin D. Huitema, Robbert G.M. Bredius, Yilin Jiang, Kevin J. Curran, Andromachi Scaradavou, Maria I. Cancio, Elizabeth Klein, Wouter J. Kollen, Dorine Bresters, Friso G.J. Calkoen, A. Birgitta Versluijs, C. Michel Zwaan, Jaap Jan Boelens, Caroline A. Lindemans
Blood Advances, 2025, vol. 9, p.2344-2353

Quantitative analysis of DNDI-6174 using UPLC-MS/MS Wietse M. Schouten, Katrien Van Bocxlaer, Hilde Rosing, Alwin D.R. Huitema, Jos H. Beijnen, Jadel M. Kratz, Charles E. Mowbray, Thomas P.C. Dorlo
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2025, vol. 1262

Implementing Pre-Emptive Pharmacogenetics Emma C Bernsen, Eugène T P Verwiel, Maaike van der Lee, Jesse J Swen, Marcel Santoso, Leiah J Brigitha, Rick Admiraal, Bastiaan B J Tops, Alwin D R Huitema, Patrick Kemmeren, Jayne Y Hehir-Kwa, Lidwien M Hanff, Meta H M Diekstra
Clinical Pharmacology and Therapeutics, 2025, vol. 118, p.438-448

Pharmacokinetic boosting of olaparib Joanneke K. Overbeek, Niels A.D. Guchelaar, Ma Ida Mohmaed Ali, Muriëlle Sark, Carolien Hovenier, Wietske Kievit, Marjolijn J.L. Ligtenberg, Petronella B. Ottevanger, Haiko J. Bloemendal, Stijn L.W. Koolen, Ron H.J. Mathijssen, Ingrid A. Boere, Alwin D.R. Huitema, Gabe S. Sonke, Frans L. Opdam, Rob ter Heine, Nielka P. van Erp
Contemporary Clinical Trials Communications, 2025, vol. 45

Fellowships & Awards

2015 Galenus research prize

2014 Huizinga penning of the Dutch Association of Hospital Pharmacists