Alwin Huitema

Full Professor

Strategic program(s):

Contact

ahuitem8@umcutrecht.nl

Pure profile

Research groups

Clinical pharmacy research

Research aim

The mission of the clinical pharmacy program is to explain, predict and improve patients’ response to pharmacotherapeutic treatment using clinical pharmacological and clinical pharmacoepidemiological approaches.

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Recent publications

All publications

Added prognostic value of circulating tumor cell numbers in CSF of patients with leptomeningeal metastasis from epithelial tumors Emma van Kessel, Noor Woerdman, Dick Pluim, Bojana Milojkovic Kerklaan, Daan van den Broek, Alwin D R Huitema, Dieta Brandsma
European Journal of Cancer, 2025, vol. 220

Advancing Therapeutic Drug Monitoring for Oral Targeted Anticancer Drugs Marinda Meertens, Hilde Rosing, Neeltje Steeghs, Jos H Beijnen, Alwin D R Huitema
Biomedical Chromatography, 2025, vol. 39

Palbociclib exposure in relation to efficacy and toxicity in patients with advanced breast cancer S. M. Buijs, M. I. Mohmaed Ali, E. Oomen-de Hoop, C. L. Braal, N. Wortelboer, A. van Ommen-Nijhof, G. S. Sonke, I. R. Konings, A. Jager, N. Steeghs, H. Siebinga, R. H.J. Mathijssen, A. D.R. Huitema, S. L.W. Koolen
ESMO open, 2025, vol. 10

An ultra-sensitive liquid chromatography tandem mass spectrometry method for the simultaneous quantification of 2H 6-alectinib and alectinib in human plasma to support a microtracer food-effect trial. L T van der Heijden, M M Tibben, M I Mohmaed Ali, L G J Aardenburg, N Steeghs, J H Beijnen, H Rosing, A D R Huitema
Journal of Chromatography B, 2025, vol. 1253

Pharmacokinetic exposure and treatment outcomes of lenvatinib in patients with renal cell carcinoma and differentiated thyroid carcinoma Marinda Meertens, Eline L. Giraud, Esbar Hassan, Sybrand W.J. Zielhuis, Tiemen T. Snels, Ingrid M.E. Desar, Janneke E.W. Walraven, Sofie Wilgenhof, Johannes V. van Thienen, Jan Paul de Boer, Neeltje Steeghs, Nielka P. van Erp, Alwin D.R. Huitema
Cancer Chemotherapy and Pharmacology, 2025, vol. 95

ADMETTRE MTX-studie Julia E. Möhlmann, Sytze de Roock, Annelies C. Egas, Evelien ter Weijden, Martijn J.H. Doeleman, Alwin D.R. Huitema, Joost F. Swart, Matthijs van Luin
Pharmaceutisch Weekblad, 2024, vol. 159, p.28-33

Fellowships & Awards

2015 Galenus research prize

2014 Huizinga penning of the Dutch Association of Hospital Pharmacists