Alwin Huitema

Full Professor

Strategic program(s):

Contact

ahuitem8@umcutrecht.nl

Pure profile

Research groups

Clinical pharmacy research

Research aim

The mission of the clinical pharmacy program is to explain, predict and improve patients’ response to pharmacotherapeutic treatment using clinical pharmacological and clinical pharmacoepidemiological approaches.

Go to group

Recent publications

All publications

Pharmacokinetic exposure and treatment outcomes of lenvatinib in patients with renal cell carcinoma and differentiated thyroid carcinoma Marinda Meertens, Eline L. Giraud, Esbar Hassan, Sybrand W.J. Zielhuis, Tiemen T. Snels, Ingrid M.E. Desar, Janneke E.W. Walraven, Sofie Wilgenhof, Johannes V. van Thienen, Jan Paul de Boer, Neeltje Steeghs, Nielka P. van Erp, Alwin D.R. Huitema
Cancer Chemotherapy and Pharmacology, 2025, vol. 95

An ultra-sensitive liquid chromatography tandem mass spectrometry method for the simultaneous quantification of 2H 6-alectinib and alectinib in human plasma to support a microtracer food-effect trial. L T van der Heijden, M M Tibben, M I Mohmaed Ali, L G J Aardenburg, N Steeghs, J H Beijnen, H Rosing, A D R Huitema
Journal of Chromatography B, 2025, vol. 1253

Palbociclib exposure in relation to efficacy and toxicity in patients with advanced breast cancer S. M. Buijs, M. I. Mohmaed Ali, E. Oomen-de Hoop, C. L. Braal, N. Wortelboer, A. van Ommen-Nijhof, G. S. Sonke, I. R. Konings, A. Jager, N. Steeghs, H. Siebinga, R. H.J. Mathijssen, A. D.R. Huitema, S. L.W. Koolen
ESMO open, 2025, vol. 10

Effect of clofarabine and fludarabine exposure on outcome after pediatric allogeneic hematopoietic cell transplantation Linde Dekker, Coco de Koning, Laura Nijstad, Kim van der Elst, Rick Admiraal, Birgitta Versluijs, Jaap-Jan Boelens, Alwin Huitema, Caroline Lindemans, Stefan Nierkens
Blood Neoplasia, 2024, vol. 1

Leishmania blood parasite dynamics during and after treatment of visceral leishmaniasis in Eastern Africa Luka Verrest, Séverine Monnerat, Ahmed M. Musa, Jane Mbui, Eltahir A.G. Khalil, Joseph Olobo, Monique Wasunna, Wan Yu Chu, Alwin D.R. Huitema, Henk D.F.H. Schallig, Fabiana Alves, Thomas P.C. Dorlo
PLoS neglected tropical diseases, 2024, vol. 18

Tocilizumab Dose Tapering Based on a Model-Based Algorithm is Feasible in Clinical Practice Femke Hooijberg, Zohra Layegh, Maureen Leeuw, Laura Boekel, Stefan P.H. Van Den Berg, Jill Ruwaard, Carla Bastida, Alwin D.R. Huitema, Sara Pel, Ori Elkayam, Annick De Vries, Mike Nurmohamed, Theo Rispens, Thomas P.C. Dorlo, Gertjan Wolbink
Therapeutic drug monitoring, 2024, vol. 46, p.410-414

Fellowships & Awards

2015 Galenus research prize

2014 Huizinga penning of the Dutch Association of Hospital Pharmacists