Wim Otte

Associate Professor

Strategic program(s):

Biography

Wim Otte is clinical epidemiologist at the UMC Utrecht Brain Center, and specialized in the statistics of predictive modeling research. He advocates open science and Bayesian inference. His recent work is dedicated to epilepsy-related clinical questions with sidesteps in the field of hearing disabilities, meta-research, and philosophy of science.

Strategic program(s):

Contact

wotte@umcutrecht.nl

Pure profile

Research groups

Personalized prediction, treatment and genetics in epilepsy

Research aim

We develop personalized methods for diagnosing, treating, and predicting outcome in epilepsy. Our aim is to better control seizures, treat comorbidities, and improve quality of life with a precision medicine approach in all people with epilepsy.

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Recent publications

All publications

Development of personas to tailor prehabilitation care for patients undergoing cancer surgery Karin Valkenet, Miriam van der Velde, Petra Bor, Edwin Geleijn, Willem M. Otte, Germijn Heijnen, Ad Kerst, Anne Marie Pierik-van Roest, Rik Bijl, Marije Marsman, Marike van der Leeden
Internet Interventions, 2026, vol. 44

Timing for Starting Antiseizure Medication Withdrawal After Epilepsy Surgery in Adults Carolina Ferreira-Atuesta, Jane De Tisi, Andrew William Mcevoy, Anna Miserocchi, Jean Khoury, Ruta Yardi, Deborah Vegh, James Thomas Butler, Hamin John Lee, Victoria Ives-Deliperi, Yi Yao, Feng Peng Wang, Xiaobin Zhang, Lubna Shakhatreh, Pakeeran Siriratnam, Andrew Neal, Arjune Sen, Maggie Tristram, Bernard Liem, Elizabeth Neethu Varghese, Wendy Beatrice Biney, William P. Gray, Catarina Correia Rodrigues, Ana Rita Peralta, Alexandre Rainha Campos, António Jdc Goncalves-Ferreira, José Pimentel, Vít Všianský, Juan Fernando Arias, Mohsen Farazdaghi, Robert Terziev, Krishna Ranjith Kadali, Kristina Koenig, Marcellina Haeberlin, Willem M. Otte, Fergus Rugg-Gunn, Samuel W. Terman, Kees P.J. Braun, Lukas L. Imbach, Ali A. Asadi-Pooya, Walter Gonzalez-Salazar, Martin Pail, Carla C. Bentes, Khalid Hamandi, Terence J. O'Brien, Piero Perucca, Chen Yao, Richard J. Burman, Lara E. Jehi, John S. Duncan, Josemir W. Sander, Matthias Koepp, Marian Galovic
Neurology, 2026, vol. 106

Spectral entropy variability of intraoperative electrocorticography predicts outcome after epilepsy surgery in people with focal cortical dysplasia Eline V Schaft, Sem Hoogteijling, Dongqing Sun, Cyrille H Ferrier, Pieter van Eijsden, Wim M Otte, Galia Anguelova, Nick F Ramsey, Maryse A Van't Klooster, Maeike Zijlmans,
Epilepsia, 2026, vol. 67, p.2117-2130

Reliability and state-dependency of EEG connectivity, complexity and network characteristics L. S. Dominicus, D. Y. Lodema, B. Oranje, M. G. Zandstra, A. P.C. Hermans, L. Imhof, W. M. Otte, A. Hillebrand, K. Ambrosen, C. J. Stam, B. H. Ebdrup, E. van Dellen
Scientific Reports, 2025, vol. 15

Clobazam versus corticosteroid for developmental and epileptic encephalopathy with spike-wave activation in sleep ((D)EE-SWAS) Marleen M L van Arnhem, Linde J Vijn, Guido Rubboli, Marianne Søndergaard Khinchi, Petia Dimova, Emilio Perucca, Valentina De Giorgis, Liisa Metsähonkala, Georgia Ramantani, Anna Jansen, Richard Chin, Lieven Lagae, Alexis Arzimanoglou, Wim M Otte, Frans S S Leijten, Heleen C van Teeseling, Kees P J Braun, Floor E Jansen, Bart van den Munckhof
Epilepsia, 2025, vol. 67, p.634-645

The use of IPD meta-analysis in maternal health prognostics Willem M Otte
Lancet (London, England), 2025, vol. 406, p.1926-1927

External positions

Dovenpastoraat - Geen, behalve dat door crisispastoraat werktijden mogelijk afgestemd moeten worden - Protestantse Kerk Nederland, Dienstencentrum