Wim Otte

Associate Professor

Strategic program(s):

Biography

Wim Otte is clinical epidemiologist at the UMC Utrecht Brain Center, and specialized in the statistics of predictive modeling research. He advocates open science and Bayesian inference. His recent work is dedicated to epilepsy-related clinical questions with sidesteps in the field of hearing disabilities, meta-research, and philosophy of science.

Strategic program(s):

Contact

wotte@umcutrecht.nl

Pure profile

Research groups

Personalized prediction, treatment and genetics in epilepsy

Research aim

We develop personalized methods for diagnosing, treating, and predicting outcome in epilepsy. Our aim is to better control seizures, treat comorbidities, and improve quality of life with a precision medicine approach in all people with epilepsy.

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Recent publications

All publications

Structural and effective brain connectivity in focal epilepsy S. B. Jelsma, M. Zijlmans, I. B. Heijink, F. W.A. Hoefnagels, M. Raemaekers, W. M. Otte, N. E.C. van Klink, D. van Blooijs
Neuroimage: Reports, 2025, vol. 5

Blueprint for clinical N-of-1 strategies with off-label precision treatments in monogenic epilepsies Victoria M Defelippe, Eva H Brilstra, Willem M Otte, Ghislaine J M W van Thiel, Helen J Cross, Finbar O'Callaghan, Valentina De Giorgis, Emilio Perucca, Kees P J Braun, Floor E Jansen
Orphanet Journal of Rare Diseases, 2025, vol. 20

Anti-seizure medication is a minor causative factor in behavioral problems of children with tuberous sclerosis complex H. M. Hulshof, J. K. Heijstek, W. M. Otte, H. Bruining, K. P.J. Braun, F. E. Jansen
Epilepsy and Behavior, 2025, vol. 168

Exploring determinants of time to school re-entry after pediatric epilepsy surgery Evangeline A. Huis in 't Veld, Olga Braams, Willem M. Otte, Peter van Rijen, Kees P.J. Braun, Renske Schappin
Epilepsy and Behavior Reports, 2025, vol. 30

Advancing treatment response prediction in first-episode psychosis Livia Dominicus, Melissa Zandstra, Josephine Franse, Wim Otte, Arjan Hillebrand, Simone de Graaf, Karen Ambrosen, Birte Yding Glenthøj, Andrew Zalesky, Kirsten Borup Bojesen, Mikkel Sørensen, Floortje Scheepers, Cornelis Stam, Bob Oranje, Bjorn Ebdrup, Edwin van Dellen
Psychiatry and Clinical Neurosciences, 2025, vol. 79, p.187-196

Is the Machine Surpassing Humans? Large Language Models, Structuralism, and Liturgical Ritual: A Position Paper Marcel Barnard, Wim Otte
International Journal of Practical Theology, 2024, vol. 28, p.289-306

External positions

Dovenpastoraat - Geen, behalve dat door crisispastoraat werktijden mogelijk afgestemd moeten worden - Protestantse Kerk Nederland, Dienstencentrum