Profile photo Frank Visseren

Frank Visseren

Full Professor

Strategic program(s):

Biography

Frank Visseren (1965) is Internist, Epidemiologist and Professor in Vascular Medicine at the University Medical Center in Utrecht. He is head of the Department of Vascular Medicine and responsible for patient care, research, and teaching. The Department of Vascular Medicine at the UMC Utrecht consists of Internists, Fellows, Research Nurses and PhD students. His main research interest is in the field of insulin resistance and vascular diseases and consists of basic, translational and epidemiologic research covering etiology, therapy, prognosis and diagnosis. There is a focus on (visceral) adipose tissue and development of atherosclerosis, atherotrombosis and diabetes. An other research focus is on translating the results of large clinical trials to invidivual patients, in collaboration with (inter)national partners. He is (co-)author of over 300 publications and associate editor of 2 scientific journals. The GCP certified research unit of the Department of Vascular Medicine performs state-of-the-art non-invasive vascular imaging tests including FMD, FBF, PWV, fingertip plethysmography, IMT and HRV. There is broad experience with industry-sponsored clinical trials in the field of Vascular Medicine, Cardiology and Diabetology and he also serves as sponsor of multi-national investigator initiated studies. He is the clinical director of the Second Manifestations of ARTerial disease (SMART) cohort at the UMC Utrecht. This is a cohort with over 13,000 patients with vascular diseases and/or type 2 diabetes or severe hypertension or familial hyperlipidemia, growing with 800 patients annually, for etiologic, prognostic, diagnostic and therapeutic research. He was (co-)supervisor of 30 thesis and currently involved in the supervision of 11  PhD students.

The clinical work of the Department of Vascular Medicine is concentrated around patients at high risk for the development of cardiovascular diseases including patients with Familial Hypercholesterolemia, patients with therapy-resistant hypertension and patients with diabetes and vascular disease. He strongly believes in a multidisciplinary, patient-centered approach in the treatment of patients at high risk for the development of (new) vascular diseases.

Teaching covers first year Medical Students to clinical specialty training in Vascular Medicine. He is member of the Concilium Medicinae Internae and chairman of the section Vascular Medicine of the Dutch Internal Medicine Society.

Research groups

Utrecht cardiovascular cohorts – second manifestations of arterial disease (UCC-SMART)

Research aim

The aim of the study is to assess important determinants and the prognosis of cardiovascular disease progression.

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Recent publications

First quinquennium completed Magnus Bäck, Maciej Banach, Frieder Braunschweig, Salvatore De Rosa, Frank A. Flachskampf, Thomas Kahan, Daniel F.J. Ketelhuth, Patrizio Lancellotti, Susanna C. Larsson, Linda Mellbin, Gianluigi Savarese, Annette Schophuus Jensen, Karolina Szummer, Denis Wahl, Ana Almeida, Marie Luce Bochaton-Piallat, Mats Börjesson, Ronny Buechel, Emmanouil Charitakis, Arrigo Cicero, Domenico D'Amario, Christian de Chillou, Jérémy Fauconnier, Nicolas Girerd, Anders Gottsäter, Joerg Herrmann, Christian Jung, Seth Martin, Edit Nagy, John Pernow, Davide Stolfo, Giuseppe Vergaro, Michal Zembala, Andre Zimerman, Harry Björkbacka, Haran Burri, Kevin Damman, Marat Fudim, Bruna Gigante, Patrick Lacolley, Gustavs Latkovskis, Sven Christian Pawelzik, Veronique Regnault, Leyla Elif Sade Akdogan, Marish Oerlemans, F. L.J. Visseren, Stefan Koudstaal,
European heart journal open, 2026, vol. 6
Multinational validation of the PREVENT and SCORE2 cardiovascular risk equations across 6.4 million individuals Brendon L. Neuen, Rupert W. Major, Morgan E. Grams, Yingying Sang, Josef Coresh, Shoshana H. Ballew, Aditya Surapaneni, Natalia Alencar de Pinho, Johan Ärnlöv, Clare Arnott, Samira Bell, Jarett Berry, Hermann Brenner, Elizabeth Ciemins, Alexander R. Chang, Mary Cushman, James A. de Lemos, Juan Miguel Diaz-Tocados, Alfredo E. Farjat, Robert A. Fletcher, Ron T. Gansevoort, Hiddo J.L. Heerspink, William G. Herrington, Chuan Hong, Edward J. Horwitz, Shih Jen Hwang, Simerjot K. Jassal, Philip A. Kalra, Ronit Katz, Sadiya S. Khan, Csaba P. Kovesdy, Florian Kronenberg, Jennifer S. Lees, Donald M. Lloyd-Jones, Jose Geraldo Mill, David M.J. Naimark, Chiadi Ndumele, Kevan R. Polkinghorne, Bruce M. Psaty, Patrick Schloemer, Michael G. Shlipak, Prabin Shrestha, Zean Song, Natalie Staplin, Dominik Steubl, Priya Vart, Frank L.J. Visseren, Mark Woodward, Kazumasa Yamagishi, Robin W.M. Vernooij, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,
Nature medicine, 2026, vol. 32, p.2629-2638
An online, Predominantly Plant-based, Dietary Intervention for Improving Cardiovascular Risk Lukas L F Hoes, Johanna M Geleijnse, Remy H H Bemelmans, Alex F Muller, Wendela L de Ranitz-Greven, Thomas van Sloten, Frank L J Visseren, Charlotte Koopal
American Heart Journal, 2026, vol. 298
The relationship between the EAT-Lancet dietary pattern and risk of cardiovascular events in patients with established cardiovascular disease Lukas L F Hoes, Chiara Colizzi, Yvonne T van der Schouw, Johanna M Geleijnse, Jannick A N Dorresteijn, Manon G van der Meer, Martin Teraa, Frank L J Visseren, Charlotte Koopal
European Journal of Nutrition, 2025, vol. 64
Prognostic Performance of a Modified HFA-ICOS Tool for Prediction of Cardiovascular Complications in Cancer Patients Mari Nordbø Gynnild, Victoria Vinje-Jakobsen, Joris Holtrop, Steven H J Hageman, Espen Holte, Geeta Gulati, Siri Lagethon Heck, Jannick A N Dorresteijn, Frank L J Visseren, Unn Merete Fagerli, Sunil Raj, Havard Dalen, Torbjørn Omland, Torgeir Wethal
JACC: Advances, 2025, vol. 4
Dementia Risk in People With Type 1 Diabetes and Associated Risk Factors Milena Jancev, Björn Eliasson, Hertzel C. Gerstein, Katarina Eeg-Olofsson, Tali Cukierman-Yaffe, Geert Jan Biessels, J. Hans DeVries, Frank L.J. Visseren, Naveed Sattar, Thomas T. van Sloten
Diabetes Care, 2025, vol. 48, p.1888-1895

External positions

Member National guideline committee Cardio Vascular Risk management (CVRM) - ja - National guideline committee (CVRM)

Lid richtlijn commissie addendum dyslipidemie bij de richtlijn CVRM - De inhoud van deze richtlijn valt binnen het expertise gebied van de Vasculaire Geneeskunde - Kennisinstituut Medisch Specialisten en de Nederlandse Int

Member board Vascular Medicine, Dutch Internal Medicine Association (NIV - ja - NIV