Tim Sakkers

Researcher/Postdoc

Strategic program(s):

Contact

tsakker4@umcutrecht.nl

Pure profile

Research groups

Cardiovascular disease in women

Research aim

Our group's aim is to translate knowledge from experimental cardiovascular research to improve womens's cardiovascular health.

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Recent publications

All publications

Genetically determined ancestry associates with morphological and molecular carotid plaque features Nima Fahim, Tim R. Sakkers, Floor B.H. van der Zalm, Joost Hoekstra, Dominique P.V. de Kleijn, Michal Mokry, Jose Verdezoto Mosquera, Gerard Pasterkamp, Hester M. den Ruijter, Clint L. Miller, Jessica van Setten, Sander W. van der Laan
Atherosclerosis, 2026, vol. 415

Atherosclerotic Fibrous Plaques in Women Present ECM Remodeling Linked to TGF-β Tim R Sakkers, Eloi Mili, Hanna Winter, Daniek Kapteijn, R Noah Perry, Nicolas Barbera, Kelsey Watts, Inês R Dias, Denitsa Meteva, Marian Wesseling, Barend M Mol, Gert J de Borst, Dominique P V de Kleijn, Sander W van der Laan, Mete Civelek, Stephen J White, Lars Maegdefessel, Manuel Mayr, Gerard Pasterkamp, Michal Mokry, Ernest Diez Benavente, Hester M den Ruijter
Circulation research, 2026, vol. 138

Women's heart disease research in the netherlands Elisa Dal Canto, N Charlotte Onland-Moret, Sanne A E Peters, Bryn Hummel, Irene G van Valkengoed, Paula M C Mommersteeg, Jeanine Roeters-van Lennep, Marte van der Bijl, Chahinda Ghossein-Doha, Frans H Rutten, Yolande Appelman, Julie A E van Oortmerssen, Maryam Kavousi, Diantha J M Schipaanboord, Tijn Jansen, Denise Peeters, Tim R Sakkers, Elize A M de Jong, Behruz Yosofi, Veroni van Es, Irene Göttgens, Tim P van de Hoef, Sabine Oertelt-Prigione, Eric Boersma, Peter Damman, Hester M den Ruijter
Netherlands Heart Journal, 2025, vol. 33, p.395-403

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans Ernest Diez Benavente, Robin J G Hartman, Tim R Sakkers, Marian Wesseling, Yannicke Sloots, Lotte Slenders, Arjan Boltjes, Barend M Mol, Gert J de Borst, Dominique P V de Kleijn, Koen H M Prange, Menno P J de Winther, Johan Kuiper, Mete Civelek, Sander W van der Laan, Steve Horvath, Charlotte Onland-Moret, Michal Mokry, Gerard Pasterkamp, Hester M den Ruijter
Arteriosclerosis, Thrombosis, and Vascular Biology, 2024, vol. 44, p.1419-1431

Sex differences in the genetic and molecular mechanisms of coronary artery disease Tim R Sakkers, Michal Mokry, Mete Civelek, Jeanette Erdmann, Gerard Pasterkamp, Ernest Diez Benavente, Hester M den Ruijter
Atherosclerosis, 2023, vol. 384

The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal transition and its involvement in atherosclerosis M. Wesseling, T. R. Sakkers, S. C.A. de Jager, G. Pasterkamp, M. J. Goumans
Vascular pharmacology, 2018, vol. 106, p.1-8