Profile photo Talitha Spanjersberg

Talitha Spanjersberg

PHD Candidate - OIO

Biography

In November 2021, I started as a PhD candidate at the department of Cardiology supervised by Frank van Steenbeek and Magdalena Harakalova as my co-promotors and Folkert Asselberg and Jolanda van der Velden as my promotors. My project is part of the DCVA Double Dose consortium, a collaboration between 5 academic medical centres in the Netherlands. This consortium aims to unravel the mechanism by which cardiomyopathy-causing mutations lead to ultrastructural changes in cardiomyocytes. My role in this consortium is to look at the influence of vasculature on the cardiomyocytes during heart failure.

During my Veterinary Medicine studies, I discovered the great potential of translational multi-species studies. The opportunity to impact different levels such as human and veterinary health and societal aspects inspired my decision for a career path in translational research.

Recent publications

Phenotypic patterns in feline heart failure Talitha C.F. Spanjersberg, Alma H. Hulsman, Guy C.M. Grinwis, Babette Janssen, C. Nina van der Wilt, Rogier J.A. Veltrop, Christian J.B. Snijders Blok, Claudia Rozendom, Paul J. Besseling, Jolanda van der Velden, Pim van der Harst, Magdalena Harakalova, Frank G. van Steenbeek
iScience, 2026, vol. 29
Protocol for fibrin-based endothelial-cardiomyocyte co-culture in a microfluidic device Talitha C.F. Spanjersberg, Aram Klaassen, Richard Wubbolts, Christian G.M. van Dijk, Jolanda van der Velden, Rogier J.A. Veltrop, Pim van der Harst, Magdalena Harakalova, Frank G. van Steenbeek
STAR protocols, 2026, vol. 7
Quantitative and qualitative histopathological analysis of myocardial tissue in canine myxomatous mitral valve disease and dilated cardiomyopathy Sorawit Phetariyawong, Jens Häggström, Fredrik Södersten, Talitha C.F. Spanjersberg, Åsa Ohlsson, Erik Axelsson, Magdalena Harakalova, Frank G. van Steenbeek, Ingrid Ljungvall
Veterinary Journal, 2026, vol. 317
Population and family data support TNNT2 p.Arg288Cys as an intermediate effect variant in hypertrophic cardiomyopathy Talitha C F Spanjersberg, Fahima Hassanzada, Jan D H Jongbloed, Dennis Dooijes, J Peter van Tintelen, Folkert W Asselbergs, Pim van der Harst, Frank G van Steenbeek, Magdalena Harakalova, Karin Y van Spaendonck-Zwarts, Marion van Vugt
International Journal of Cardiology, 2026, vol. 452
Locational memory of macrovessel vascular cells is transcriptionally imprinted Talitha C F Spanjersberg, Loes A Oosterhoff, Hedwig S Kruitwagen, Noortje A M van den Dungen, Johannes C M Vernooij, Folkert W Asselbergs, Michal Mokry, Bart Spee, Magdalena Harakalova, Frank G van Steenbeek
Scientific Reports, 2023, vol. 13