Stefan Willems

Associate Professor - medical

Biography

Dr Stefan Willems was trained in medicin (2003 cum laude Catholic University Leuven) with a PhD in molecular pathology (2010, Leiden University) and specialized in pathology (2011, LUMC). After postdoc positions at Harvard Medical School (Gygilab) and NKI  (Bernardslab) he has been working as a pathologist with special interest in molecular pathology and diagnostics. He is co-director of the molecular pathology lab in the University Medical Center Utrecht. He is associate professor in pathology and head of the molecular head and neck cancer line within the UMC Utrecht (1 postdoc, 8 PhDs). He is also affiliated with the department of pathology of the NKI-AvL and performs here translational head and neck research. He is board member of the PALGA Foundation.

Recent publications

Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer L W de Boo, K Jóźwiak, N D Ter Hoeve, P J van Diest, M Opdam, Y Wang, M K Schmidt, V de Jong, S Kleiterp, S Cornelissen, D Baars, R H T Koornstra, E D Kerver, T van Dalen, A D Bins, A Beeker, S M van den Heiligenberg, P C de Jong, S D Bakker, R C Rietbroek, I R Konings, R Blankenburgh, R M Bijlsma, A L T Imholz, N Stathonikos, W Vreuls, J Sanders, E H Rosenberg, E A Koop, Z Varga, C H M van Deurzen, A L Mooyaart, A Córdoba, E Groen, J Bart, S M Willems, V Zolota, J Wesseling, A Sapino, E Chmielik, A Ryska, A Broeks, A C Voogd, E van der Wall, S Siesling, R Salgado, G M H E Dackus, M Hauptmann, M Kok, S C Linn
ESMO open, 2024, vol. 9
Jaw Bone Invasion of Oral Squamous Cell Carcinoma Is Associated with Osteoclast Count and Expression of Its Regulating Proteins in Patients and Organoids Willem W B de Kort, Wisse E Haakma, Robert J J van Es, Debby Gawlitta, Else Driehuis, Merel Gansevoort, Stefan M Willems
Journal of Clinical medicine, 2023, vol. 12, p.1-14
Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification Rosemary Millen, Willem W.B. De Kort, Mandy Koomen, Gijs J.F. van Son, Roán Gobits, Bas Penning de Vries, Harry Begthel, Maurice Zandvliet, Patricia Doornaert, Cornelis P.J. Raaijmakers, Maarten H. Geurts, Sjoerd G. Elias, Robert J.J. van Es, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Onno Kranenburg, Else Driehuis, Hans Clevers
Med, 2023, vol. 4, p.290-310.e12
Author Correction Alessio Marcozzi, Myrthe Jager, Martin Elferink, Roy Straver, Joost H van Ginkel, Boris Peltenburg, Li-Ting Chen, Ivo Renkens, Joyce van Kuik, Chris Terhaard, Remco de Bree, Lot A Devriese, Stefan M Willems, Wigard P Kloosterman, Jeroen de Ridder
npj Genomic Medicine, 2023, vol. 8
Using Intratumor Heterogeneity of Immunohistochemistry Biomarkers to Classify Laryngeal and Hypopharyngeal Tumors Based on Histologic Features Hilde J G Smits, Lilian N Ruiter, Gerben E Breimer, Stefan M Willems, Marielle E P Philippens
Modern Pathology, 2023, vol. 36
p-mTOR, p-ERK and PTEN Expression in Tumor Biopsies and Organoids as Predictive Biomarkers for Patients with HPV Negative Head and Neck Cancer W. W.B. de Kort, E. J. de Ruiter, W. E. Haakma, E. Driehuis, L. A. Devriese, R. J.J. van Es, S. M. Willems
Head and neck pathology, 2023, vol. 17, p.697-707

External positions

Pathologist NKI-AvL