Profile photo Frans Rutten

Frans Rutten

Full Professor

Strategic program(s):


I hold a position as professor in general practice. I lead a research group focusing on the management of cardiovascular disease in primary care, from early detection of disease and risk-stratification to risk-based treatment.

My teaching activities cover being involved in educational programs at the bachelor (CRU) and master (Summa) level at the medical school, and also being involved in the specialty training and post-graduate training courses of general practitioners. I am a member of the steering committee of the Dutch 'kaderopleiding hart- en vaatziekten' for general practitioners and actively participate in its teaching program.

My research group has contributed to improving the diagnosis of heart failure and deep venous thrombosis in the primary care setting, and our studies have been used as building blocks for diagnostic algorithms recommended by the (inter)national guidelines regarding these diseases. By showing that unrecognized heart failure is common in patients with chronic obstructive pulmonary disease (COPD) and also in type 2 diabetes, our work has helped revolutionize clinical practice. I contributed to the development of guidelines on heart failure, atrial fibrillation, left ventricular hypertrophy and Non-ST elevated Acute Coronary Syndrome for the European Society of Cardiology, and also to the educational practice guideline documents on heart failure and atrial fibrillation for the European Primary Care Cardiovascular Society. Over the years I have been actively involved in working groups of the Heart Failure Association of the European Society of Cardiology, and was instrumental in translating the interactive website '' to Dutch, making it understandable for patients and their carers.

Within the UMC Utrecht, I am member of the coreteam of the theme ('speerpunt') Circulatory Health.

I managed to acquire ample funding for the clinical research activities of our research group. In 2017 I became the successful recipient of a research grant of Cardiovascular Research Netherlands (CVON), with myself being the main applicant of a consortium that will focus on early diagnosis of heart failure, atrial fibrillation and coronary artery disease in patients who participate in primary care disease management programs for COPD or type 2 diabetes. The aim is to facilitate early treatment and improve prognosis by preventing acute cardiovascular events such as acute heart failure, stroke and acute coronary syndrome.

I am coordinator of the Research Programme Cardiovascular Health of the Julius Center for Health Sciences and Primary Care of the UMC Utrecht. In addition I am member of the leadership team of the Julius Center, chair of research of the department of general practice, and board member of the management team of the department of General Practice within the Julius Center.

I collaborate with other departments of the Julius Center (epidemiology, public health and nursing sciences) and the clinical departments of Cardiology, Vascular Surgery, Vascular Medicine and renal disease, as well as with the department of imaging.

Research groups

Cardiovascular health in general practice

Research aim

Improve cardiovascular health of people by high-quality research aimed at early detection of cardiovascular disease, risk-stratification, risk-based treatment, and primary care innovation.

Go to group

Recent publications

Home-based management of hypoxaemic COVID-19 patients Josi A Boeijen, Alma C van de Pol, Rick T van Uum, Roderick P Venekamp, Karin Smit, Karin A H Kaasjager, Robert van den Broek, Wilma Bijsterbosch, Lisette Schoonhoven, Frans H Rutten, Dorien L M Zwart
BMJ Open, 2024, vol. 14, p.e079778
Incomplete and possibly selective recording of signs, symptoms, and measurements in free text fields of primary care electronic health records of adults with lower respiratory tract infections Merijn H. Rijk, Tamara N. Platteel, Marissa M.M. Mulder, Geert Jan Geersing, Frans H. Rutten, Maarten van Smeden, Roderick P. Venekamp, Tuur M. Leeuwenberg
Journal of Clinical Epidemiology, 2024, vol. 166, p.1-10
RELEASE-HF study Jorna van Eijk, Kim Luijken, Tiny Jaarsma, Johannes B Reitsma, Ewoud Schuit, Geert W J Frederix, Lineke Derks, Jeroen Schaap, Frans H Rutten, Jasper Brugts, Rudolf A de Boer, Folkert W Asselbergs, Jaap C A Trappenburg,
BMJ Open, 2024, vol. 14
Heart failure with preserved ejection fraction Patricia Campbell, Frans H Rutten, Matthew My Lee, Nathaniel M Hawkins, Mark C Petrie
Lancet (London, England), 2024, vol. 403, p.1083-1092
Predictive factors of clot propagation in patients with superficial venous thrombosis towards deep venous thrombosis and pulmonary embolism Florien Sophie-Anne van Royen, Maarten van Smeden, Sander van Doorn, Frans H Rutten, Geert-Jan Geersing
BMJ Open, 2024, vol. 14, p.1-14
Prognostic factors and prediction models for hospitalisation and all-cause mortality in adults presenting to primary care with a lower respiratory tract infection Merijn H. Rijk, Tamara N. Platteel, Teun M.C. van den Berg, Geert Jan Geersing, Paul Little, Frans H. Rutten, Maarten van Smeden, Roderick P. Venekamp
BMJ Open, 2024, vol. 14

External positions

coordinator research of the 'kaderhuisartsen Hart-en Vaatziekten'

Chair of the authorisation committee of the Dutch college of general practitioners

free-lance general practitioner

Member of the Advisory Board of the European Primary Care Cardiovascular Society

Board Member of the University Network of general practitioners, research (UNH-R)

Scientific Advisory Board Member of the Netherlands Heart Foundation

Editorial Board Member of Family Practice

Board Member and supervisor of the GP 'kaderopleiding hart- en vaatziekten'

General Practitioner in Rhenen