Profile photo René Kahn

René Kahn

Full Professor

Biography

Dr René Kahn is Professor and until 2017, was Chair of the Department of Psychiatry and Head of the Division of Neurosciences at the University Medical Center, Utrecht, The Netherlands. In 1995 he received a Fulbright Scholarship for study at Yale and subsequently did a Fellowship in Biological Psychiatry at the Montefiore Hospital and Albert Einstein College of Medicine in New York. He then moved to the Mount Sinai School of Medicine where he conducted schizophrenia research and became Unit Chief of one of the research units.

Dr Kahn has received many grants for his research into the origins and treatment of schizophrenia. His current research interests include neuroimaging in schizophrenia and the genetic dissection of complex traits in specific psychiatric disorders. He has published over 500 research papers and book chapters. He is on the editorial boards of Schizophrenia research, Schizophrenia Bulletin, Early Interventions in Psychiatry and European Neuropsychopharmacology. He was both Treasurer and Vice-President of the European College for Neuropsychopharmacology and currently is President-Elect of the Schizophrenia International Research Society. He sat on the Neuroscience andd Mental Health Board of the Medical Research Council of the UK and was on the scientific advisory group for CNS of the European Medicines Agency. He leads a large EU-funded study, OPTiMiSE, on developing a treatment algorithm in first episode schizophrenia. He is honorary lifetime professor at Jilin University in Changchun, P.R. China and a member of the Royal Netherlands Academy of Arts and Sciences.

As of January 2017, he is appointed head of the Department of Psychiatry at Icahn School of Medicine at Mount Sinai in New York. His main tasks at UMC Utrecht are now: coaching his PhD students and coordinating research projects.

Most recent key publications

1: Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, Gheorghe MD, Rybakowski JK, Galderisi S, Libiger J, Hummer M, Dollfus S, López-Ibor JJ, Hranov LG, Gaebel W, Peuskens J, Lindefors N, Riecher-Rössler A, Grobbee DE, EUFEST study group. E
2: van der Schot AC, Vonk R, Brans RG, van Haren NE, Koolschijn PC, Nuboer V, Schnack HG, van Baal GC, Boomsma DI, Nolen WA, Hulshoff Pol HE, Kahn RS. Influence of genes and environment on brain volumes in twin pairs concordant and discordant for bipolar disorder. Arch Gen Psychiatry. 2009 Feb,66(2):142-51
3: van der Schot AC, Vonk R, Brouwer RM, van Baal GC, Brans RG, van Haren NE, Schnack HG, Boomsma DI, Nolen WA, Pol HE, Kahn RS. Genetic and environmental influences on focal brain density in bipolar disorder. Brain. 2010 Sep 12
4: van Haren NE, Schnack HG, Cahn W, van den Heuvel MP, Lepage C, Collins L, Evans AC, Hulshoff Pol HE, Kahn RS Changes in cortical thickness during the course of illness in schizophrenia Arch Gen Psychiatry. 2011 Sep,68(9):871-80
5: van Haren NE, Rijsdijk F, Schnack HG, Picchioni MM, Toulopoulou T, Weisbrod M, Sauer ,H, van Erp TG, Cannon TD, Huttunen MO, Boomsma DI, Hulshoff Pol HE, Murray RM, Kahn RS. The genetic and environmental determinants of the association between brain abnormalities and schizophrenia: the schizophrenia twins and relatives consortium. Biol Psychiatry. 2012 May 15,71(10):915-21

Recent publications

The More Things Change . . René S. Kahn
The American journal of psychiatry, 2024, vol. 181, p.474-475
Cell-type deconvolution of bulk-blood RNA-seq reveals biological insights into neuropsychiatric disorders Toni Boltz, Tommer Schwarz, Merel Bot, Kangcheng Hou, Christa Caggiano, Sandra Lapinska, Chenda Duan, Marco P. Boks, Rene S. Kahn, Noah Zaitlen, Bogdan Pasaniuc, Roel Ophoff
American Journal of Human Genetics, 2024, vol. 111, p.323-337
Normative modelling of brain morphometry across the lifespan with CentileBrain Ruiyang Ge, Yuetong Yu, Yi Xuan Qi, Yu nan Fan, Shiyu Chen, Chuntong Gao, Shalaila S. Haas, Faye New, Dorret I. Boomsma, Henry Brodaty, Rachel M. Brouwer, Randy Buckner, Xavier Caseras, Fabrice Crivello, Eveline A. Crone, Susanne Erk, Simon E. Fisher, Barbara Franke, David C. Glahn, Udo Dannlowski, Dominik Grotegerd, Oliver Gruber, Hilleke E. Hulshoff Pol, Gunter Schumann, Christian K. Tamnes, Henrik Walter, Lara M. Wierenga, Neda Jahanshad, Paul M. Thompson, Sophia Frangou, Ingrid Agartz, Philip Asherson, Rosa Ayesa-Arriola, Nerisa Banaj, Tobias Banaschewski, Sarah Baumeister, Alessandro Bertolino, Stefan Borgwardt, Josiane Bourque, Daniel Brandeis, Alan Breier, Jan K. Buitelaar, Dara M. Cannon, Simon Cervenka, Patricia J. Conrod, Benedicto Crespo-Facorro, Christopher G. Davey, René S. Kahn, Iris E. Sommer, Neeltje EM van Haren,
The Lancet Digital Health, 2024, vol. 6, p.e211-e221
MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway G. A.M. Blokland, N. Maleki, J. Jovicich, R. I. Mesholam-Gately, L. E. DeLisi, J. A. Turner, M. E. Shenton, A. N. Voineskos, R. S. Kahn, J. L. Roffman, D. J. Holt, S. Ehrlich, Z. Kikinis, P. Dazzan, R. M. Murray, J. Lee, K. Sim, M. Lam, S. M.C. de Zwarte, E. Walton, S. Kelly, M. M. Picchioni, E. Bramon, N. Makris, A. S. David, V. Mondelli, A. A.T.S. Reinders, E. Oykhman, D. W. Morris, M. Gill, A. P. Corvin, W. Cahn, N. Ho, J. Liu, R. L. Gollub, D. S. Manoach, V. D. Calhoun, S. R. Sponheim, S. L. Buka, S. Cherkerzian, H. W. Thermenos, E. W. Dickie, S. Ciufolini, T. Reis Marques, N. A. Crossley, S. M. Purcell, J. W. Smoller, N. E.M. van Haren, T. Toulopoulou, G. Donohoe,
International Journal of Clinical and Health Psychology, 2024, vol. 24
Meta-analysis of epigenetic aging in schizophrenia reveals multifaceted relationships with age, sex, illness duration, and polygenic risk Anil P.S. Ori, Loes M. Olde Loohuis, Jerry Guintivano, Eilis Hannon, Emma Dempster, David St. Clair, Nick J. Bass, Andrew McQuillin, Jonathan Mill, Patrick F. Sullivan, Rene S. Kahn, Steve Horvath, Roel A. Ophoff
Clinical Epigenetics, 2024, vol. 16, p.1-14
Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ) Cassandra M J Wannan, Barnaby Nelson, Jean Addington, Kelly Allott, Alan Anticevic, Celso Arango, Justin T Baker, Carrie E Bearden, Tashrif Billah, Sylvain Bouix, Matthew R Broome, Kate Buccilli, Kristin S Cadenhead, Monica E Calkins, Tyrone D Cannon, Guillermo Cecci, Eric Yu Hai Chen, Kang Ik K Cho, Jimmy Choi, Scott R Clark, Michael J Coleman, Philippe Conus, Cheryl M Corcoran, Barbara A Cornblatt, Covadonga M Diaz-Caneja, Dominic Dwyer, Bjørn H Ebdrup, Lauren M Ellman, Paolo Fusar-Poli, Liliana Galindo, Pablo A Gaspar, Carla Gerber, Louise Birkedal Glenthøj, Robert Glynn, Michael P Harms, Leslie E Horton, René S Kahn, Joseph Kambeitz, Lana Kambeitz-Ilankovic, John M Kane, Tina Kapur, Matcheri S Keshavan, Sung-Wan Kim, Nikolaos Koutsouleris, Marek Kubicki, Jun Soo Kwon, Kerstin Langbein, Kathryn E Lewandowski, Gregory A Light, Inge Winter-van Rossum,
Schizophrenia bulletin, 2024, vol. 50, p.496-512

Fellowships & Awards

2016: Membership Committee American College of Neuropsychopharmacology

2014: Honorary Doctorate

2014: ECNP Neuropsychopharmacology Award 2014

2010: Honorary Professor

External positions

Chair of the Division of Psychiatry at the Icahn School of Medicine of Mount Sinai (ISMMS) in New York, Icahn School of Medicine at Mount Sinai (ISMMS)