Peter Krijger

Assistant Professor

Contact

pkrijger@umcutrecht.nl

Pure profile

Research groups

Functional genomics for rare genetic diseases

Research aim

Improve diagnosis and lay groundwork for precision therapies for rare genetic diseases by turning genomic findings into experimentally validated functional evidence that can guide patient care.

Go to group

Recent publications

All publications

Characterization of induced cohesin loop extrusion trajectories in living cells Ruiqi Han, Yike Huang, Michelle J. Robers, Mikhail Magnitov, Iwan Vaandrager, Amin Allahyar, Marjon J.A.M. Verstegen, Kexin Zhang, Elzo de Wit, Wouter de Laat, Peter H.L. Krijger
Nature genetics, 2025, vol. 57, p.2785–2797

Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway Peter Hl Krijger, Anastasia Tsaalbi-Shtylik, Niek Wit, Paul Cornelius Maria van den Berk, Niels de Wind, Heinz Jacobs
European Journal of Immunology, 2013, vol. 43, p.2765-2770

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance Peter H.L. Krijger, Paul C.M. Van Den Berk, Niek Wit, Petra Langerak, Jacob G. Jansen, Claude Agnès Reynaud, Niels De Wind, Heinz Jacobs
DNA repair, 2011, vol. 10, p.1051-1059

HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation Peter H.L. Krijger, Kyoo Young Lee, Niek Wit, Paul C.M. van den Berk, Xiaoli Wu, Henk P. Roest, Alex Maas, Hao Ding, Jan H.J. Hoeijmakers, Kyungjae Myung, Heinz Jacobs
DNA repair, 2011, vol. 10, p.438-444

PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells Ayal Hendel, Peter H.L. Krijger, Noam Diamant, Zohar Goren, Petra Langerak, Jungmin Kim, Thomas Reißner, Kyoo young Lee, Nicholas E. Geacintov, Thomas Carell, Kyungjae Myung, Satoshi Tateishi, Alan D'Andrea, Heinz Jacobs, Zvi Livneh
PLoS Genetics, 2011, vol. 7

Lysine residue 185 of Rad1 is a Topological but not a functional counterpart of lysine residue 164 of PCNA Niek Wit, Peter H.L. Krijger, Paul C.M. van den Berk, Heinz Jacobs
PLoS ONE, 2011, vol. 6