Profile photo Paul van Diest

Paul van Diest

Full Professor

Strategic program(s):

Biography

Paul J van Diest has been a dedicated cancer researcher since the start of his career, obtaining numerous grants a.o. from the NIH and the Dutch Cancer Society. He studied Medicine, did his PhD and pathology residency at the VU University medical center (VUMC) in Amsterdam. After obtaining his Board certification in Pathology in 1996, he became Consultant Pathologist at the Department of Pathology of the VUMC. In 1999 he was appointed Associate Professor and in 2001 to full Professor. In 2003 he moved to Utrecht to become Head of the Department of Pathology at the University Medical Center Utrecht (UMCU) where he is currently still working. He is Adjunct Professor of Oncology at the Sidney Kimmel Oncology Center at Johns Hopkins, Baltimore, USA. He serves on the editorial board of >20 international journals. He has been active in the board as secretary and president of several international societies. He has published >900 papers in peer reviewed journals, personally supervised 90 PhD theses, and has an H-index of 99. The main theme of his research is finding ways for prevention, optimized diagnosis and cure of breast cancer, both the male and female forms. He is also active in the field of implementing digital pathology and AI.

Strategic program(s):

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Research groups

Translational breast cancer research group

Research aim

We aim to optimize early diagnosis and treatment of breast cancer, especially rare breast cancers like pregnancy associated, male & lobular breast cancer. We refine tissue diagnostics with molecular techniques/AI, and apply nipple fluid/blood tests.
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AI in pathology

Research aim

To develop, validate, and implement AI in digital pathology practice
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Recent publications

Predicting response to neoadjuvant chemotherapy with liquid biopsies and multiparametric MRI in patients with breast cancer L. M. Janssen, M. H.A. Janse, B. B.L. Penning de Vries, B. H.M. van der Velden, E. J.M. Wolters-van der Ben, S. M. van den Bosch, A. Sartori, C. Jovelet, M. J. Agterof, D. Ten Bokkel Huinink, E. W. Bouman-Wammes, P. J. van Diest, E. van der Wall, S. G. Elias, K. G.A. Gilhuijs
npj Breast Cancer, 2024, vol. 10
Biomedical students' satisfaction with and engagement in laboratory e-learning support are related to their self-regulation C B Moelans, J J Geerling, R D Radersma, M J Moons, P J van Diest, M F van der Schaaf
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, 2024, vol. 52, p.262-275
The difficulty with measuring the largest melanoma tumour diameter in sentinel lymph nodes Annelien E Laeijendecker, Mary-Ann El Sharouni, Nikolaos Stathonikos, Clothaire P E Spoto, Bart A van de Wiel, Erik J E Eijken, Marijne Mulder, Antien L Mooyaart, Anna Szumera-Cieckiewicz, Daniela Mihic-Probst, Daniela Massi, Martin Cook, Senada Koljenovic, Llucia Alos, Paul J van Diest, Alexander C J van Akkooi, Willeke Blokx
Journal of Clinical Pathology, 2024, vol. 77, p.372-377
Long-term outcomes of young, node-negative, chemotherapy-naïve, triple-negative breast cancer patients according to BRCA1 status Yuwei Wang, Gwen M H E Dackus, Efraim H Rosenberg, Sten Cornelissen, Leonora W de Boo, Annegien Broeks, Wim Brugman, Terry W S Chan, Paul J van Diest, Michael Hauptmann, Natalie D Ter Hoeve, Olga I Isaeva, Vincent M T de Jong, Katarzyna Jóźwiak, Roelof J C Kluin, Marleen Kok, Esther Koop, Petra M Nederlof, Mark Opdam, Philip C Schouten, Sabine Siesling, Charlaine van Steenis, Adri C Voogd, Willem Vreuls, Roberto F Salgado, Sabine C Linn, Marjanka K Schmidt
BMC Medicine, 2024, vol. 22, p.1-14
Intertumoral heterogeneity of bifocal breast cancer Kai Finsterbusch, Paul J van Diest, Cornelia M Focke
Breast Cancer Research and Treatment, 2024, vol. 205, p.413-421
The Diagnostic Value of microRNA Expression Analysis in Detecting Intraductal Papillomas in Patients with Pathological Nipple Discharge Seher Makineli, Menno R. Vriens, Arjen J. Witkamp, Paul J. van Diest, Cathy B. Moelans
International Journal of Molecular Sciences, 2024, vol. 25

External positions

Advisory Board - Jaarlijkse meeting duur 1 dag bijwonen - Visiopharm

Advisor - AI ontwikkeling en research wordt gedaan op afdeling - PAIGE

Member of the Digital Pathology advisory board of Paige - Op basis van expertise - Paige

Contractresearch - Vanuit de expertise van mijn huidige functie - Samantree

Visiting Professor. lesgeven, opleiding AIOS uit Siena voor stage althier - Op basis expertise - University of Siena, Italy

Zie bijlage - Alles op basis van expertise in mijn functie - Varia alle inkomsten t.g.v. UMC Utrecht zie bijlage

Member of the Digital Pathology advisory board of Philips - Vanuit mijn expertise - Philips

Wetenschappelijk - Vanuit mijn expertise - Sidney Kimmel Oncology Center at Johns Hopkins