Profile photo Gerard Pasterkamp

Gerard Pasterkamp

Full Professor

Strategic program(s):

Biography

Gerard Pasterkamp, MD, is professor Experimental Cardiology and quarter maker of the Circulatory Health Research Center, UMC Utrecht. His research interests are in the field of cardiovascular biology and more specifically innovation in biomarkers. His research interests are in the field of cardiovascular biology and innovation in biomarkers and drug targets. The research group houses the largest atherosclerotic plaque biobank worldwide: Athero Express including >4000 patients. This biobank has generated new insights into determinants of plaque destabilisation. The laboratory also invests in the excavation of genetic determinants of atherosclerotic plaque characteristics. He coordinates national and EU based consortia with the aim to unravel biomarkers and mechanisms of atherosclerotic disease. His translational profile is noted in the private public consortia he is involved in. He is supervising three public private grants that have been rewarded with the aim to develop novel biomarkers and imaging technology to detect cardiac ischemia and endothelial dysfunction. In 2018 he obtained a LeDucq grant together with Prof G Owens (Virginia University) on the role of smooth muscle cell plasticity in the atherosclerotic plaque. 

Recent publications

Absence of GDF15 Aggravates Pressure Overload-Induced Cardiac Remodelling in Mice Hallmarked by Perivascular Fibrosis and Signs of Endothelial-to-Mesenchymal Transition Marian Wesseling, Gonzalo Sanchez-Duffhues, Judith J. de Haan, Jasper Tromp, Lena Bosch, J. Conny van Munsteren, Maike A.D. Brans, Joost P.G. Sluijter, Gerard Pasterkamp, Marie José Goumans, Saskia C.A. de Jager
International Journal of Molecular Sciences, 2026, vol. 27
Long-term risk of major adverse cardiovascular events after carotid endarterectomy Barend M Mol, Carolijn J M de Bresser, P V de Kleijn, Ilonca Vaartjes, Gerard Pasterkamp, Michiel L Bots, Gert J de Borst, Michiel H F Poorthuis, Yvonne Koop
European Stroke Journal, 2026, vol. 11
Genetically determined ancestry associates with morphological and molecular carotid plaque features Nima Fahim, Tim R. Sakkers, Floor B.H. van der Zalm, Joost Hoekstra, Dominique P.V. de Kleijn, Michal Mokry, Jose Verdezoto Mosquera, Gerard Pasterkamp, Hester M. den Ruijter, Clint L. Miller, Jessica van Setten, Sander W. van der Laan
Atherosclerosis, 2026, vol. 415
Workplace Pollution and Risk of Incident Coronary Artery Disease Hua Gao, Kai-Uwe Jarr, Yoko Kojima, Ting Xiong, Juyong Brian Kim, Paul Cheng, Leonardo Trasande, Annette Peters, Gerard Pasterkamp, Chiara Giannarelli, Nicholas J Leeper
2026
Spatial mapping of stability in human atherosclerosis for the next generation of patient stratification Gerard Pasterkamp, Minna U Kaikkonen, Michal Mokry
European heart journal, 2026, vol. 47, p.3733-3735
Atherosclerotic Fibrous Plaques in Women Present ECM Remodeling Linked to TGF-β Tim R Sakkers, Eloi Mili, Hanna Winter, Daniek Kapteijn, R Noah Perry, Nicolas Barbera, Kelsey Watts, Inês R Dias, Denitsa Meteva, Marian Wesseling, Barend M Mol, Gert J de Borst, Dominique P V de Kleijn, Sander W van der Laan, Mete Civelek, Stephen J White, Lars Maegdefessel, Manuel Mayr, Gerard Pasterkamp, Michal Mokry, Ernest Diez Benavente, Hester M den Ruijter
Circulation research, 2026, vol. 138

External positions

reviewerspanel/commissie Health Holland ronde oktober 2024 - reviewen en met commissie belsuiten over honorering aanvragen - Health Holland

auteur - uitgeven van een boek, maar aantal uren is niet (meer) van toepassing. werk is al gedaan - persoonlijk, geen werkgever

Voorzitter Wetenschappelijke Adviesraad - Voorzitten vergaderingen - Reuma Nederland