Profile photo Monique Nijhuis

Monique Nijhuis

Associate Professor

Strategic program(s):

Biography

Monique Nijhuis studied Molecular Biology and obtained her PhD in 1999 at the University of Utrecht on the investigation of the impact of antiretroviral therapy on HIV fitness. Following postdoctoral research training in respiratory viruses she initiated her own research line and became an associate Professor of Virology at the University Medical Center Utrecht in The Netherlands. She is heading the Translational Virology group which performs research at the interface between fundamental and clinical virology. Her research is centered on (I) Viral entry, transmission and pathogenesis (II) Mechanisms of antiviral resistance and viral evolution and (III) Viral-reservoirs and eradication. Monique Nijhuis was granted by the Netherlands Organization for Scientific Research (NWO) with the VIDI and ASPASIA award. She is a member of the IAS HIV Cure International Scientific Working Group and the scientific advisory board of the Dutch Aidsfonds and associate editor of Retrovirology. She has published over 100 papers in peer-reviewed journals and has guided technicians, PhD student, and Postdoctoral Fellows. 

She is teaching Virology in the Bachelor Biomedical Sciences and several Master and PhD programs. She has mentored numerous Bachelor and Graduate students. She is heading the Biological Safety Committee supervising several Biosafety Level III laboratories.

Recent publications

Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort Maria Salgado, Cristina Gálvez, Monique Nijhuis, Mi Kwon, E Fabian Cardozo-Ojeda, Jon Badiola, Matthew J Gorman, Laura E P Huyveneers, Victor Urrea, Alessandra Bandera, Björn-Erik Ole Jensen, Linos Vandekerckhove, Manuel Jurado, Kavita Raj, Julian Schulze Zur Wiesch, Rebeca Bailén, Johanna M Eberhard, Mitja Nabergoj, Gero Hütter, Raquel Saldaña-Moreno, Sharon Oldford, Lisa Barrett, Maria Luisa Montes Ramirez, Salisu Garba, Ravi Kumar Gupta, Boris Revollo, Christelle Ferra-Coll, Jurgen Kuball, Galit Alter, Asier Sáez-Cirión, Jose Luis Diez-Martin, Elizabeth R Duke, Joshua T Schiffer, Annemarie Wensing, Javier Martinez-Picado,
The lancet. HIV, 2024, vol. 11, p.e389-e405
Point-of-Care Tenofovir Urine Testing for the Prediction of Treatment Failure and Drug Resistance During Initial Treatment for Human Immunodeficiency Virus Type 1 (HIV-1) Infection Lucas E. Hermans, Chijioke N. Umunnakwe, Samanta T. Lalla-Edward, Shane K. Hebel, Hugo A. Tempelman, Monique Nijhuis, Willem D.F. Venter, Annemarie M.J. Wensing
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, vol. 76, p.e553-e560
Impaired SARS-CoV-2 specific T-cell response in patients with severe COVID-19 Lidewij W. Rümke, Wouter L. Smit, Ailko Bossink, Gijs J.M. Limonard, Danya Muilwijk, Lenneke E.M. Haas, Chantal Reusken, Sanne van der Wal, Bing J. Thio, Yvonne M.G. van Os, Hendrik Gremmels, Jeffrey M. Beekman, Monique Nijhuis, Annemarie M.J. Wensing, Michiel Heron, Steven F.T. Thijsen
Frontiers in Immunology, 2023, vol. 14
Virological and immunological correlates of HIV posttreatment control after temporal antiretroviral therapy during acute HIV infection Pien M. Van Paassen, Lisa Van Pul, Karlijn Van Der Straten, Ninée V.J.E. Buchholtz, Marloes Grobben, Ad C. Van Nuenen, Karel A. Van Dort, Brigitte D. Boeser-Nunnink, Mo D. Van Den Essenburg, Judith A. Burger, Matthijs Van Luin, Suzanne Jurriaans, Rogier W. Sanders, Wendy T. Swelsen, Jori Symons, Michelle J. Klouwens, Monique Nijhuis, Marit J. Van Gils, Jan M. Prins, Godelieve J. De Bree, Neeltje A. Kootstra
AIDS, 2023, vol. 37, p.2297-2304
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation Björn Erik Ole Jensen, Elena Knops, Leon Cords, Nadine Lübke, Maria Salgado, Kathleen Busman-Sahay, Jacob D. Estes, Laura E.P. Huyveneers, Federico Perdomo-Celis, Melanie Wittner, Cristina Gálvez, Christiane Mummert, Caroline Passaes, Johanna M. Eberhard, Carsten Münk, Ilona Hauber, Joachim Hauber, Eva Heger, Jozefien De Clercq, Linos Vandekerckhove, Silke Bergmann, Gábor A. Dunay, Florian Klein, Dieter Häussinger, Johannes C. Fischer, Kathrin Nachtkamp, Joerg Timm, Rolf Kaiser, Thomas Harrer, Tom Luedde, Monique Nijhuis, Asier Sáez-Cirión, Julian Schulze zur Wiesch, Annemarie M.J. Wensing, Javier Martinez-Picado, Guido Kobbe
Nature Medicine, 2023, vol. 29, p.583-587
Human microglial models to study HIV infection and neuropathogenesis Stephanie B.H. Gumbs, Raphael Kübler, Lavina Gharu, Pauline J. Schipper, Anne L. Borst, Gijsje J.L.J. Snijders, Paul R. Ormel, Amber Berdenis van Berlekom, Annemarie M.J. Wensing, Lot D. de Witte, Monique Nijhuis
Journal of Neurovirology, 2022, vol. 28, p.64-91

Fellowships & Awards

2008: Kan HIV wederom ontsnappen?