Profile photo Niels Bovenschen

Niels Bovenschen

Full Professor

Strategic program(s):


Prof. dr. Niels Bovenschen studied Medical Biology at the Free University in Amsterdam and he obtained his PhD in 2003 at Sanquin Research (Amsterdam). In 2004, he moved to the department of Pathology at the University Medical Center Utrecht (UMC Utrecht). His research group focuses on the effector immune response in eliminating tumor cells and virus-infected cells and how to improve (cancer) immunotherapy. He is in charge of the UMC Utrecht Pathology Research Laboratory and head of the Laboratory of Translational Immunology core facility Proteins. Niels was appointed as Senior Fellow in 2017 and as Principal Fellow in 2020 at Utrecht University. His mission is to engage undergraduate students in science by creating synergy between education, scientific research, and healthcare already at the early undergraduate level. Niels focuses on multidisciplinary collaboration and facilitates students to work on real-world societally relevant problems in the healthcare domain. He is examiner and coordinator of several (bio)medical educational programs and courses at the faculty of Medicine, Utrecht University. He founded the Bachelor Research Hub and Student Research Hub network. In 2019, Niels Bovenschen won the Outstanding Teacher Award of Utrecht University. He was appointed professor of Biomedical Research-based Education at the faculty of Medicine in 2021.

Research groups

Effector phase immunity

Research aim

Our research focusses on the effector immune response of cytotoxic (killer) cells in brain cancer. We aim to translate this knowledge into (cellular) immunotherapy and nanomedicines that mimic effector phase immunity to target cancer.

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Recent publications

A challenge-based interdisciplinary undergraduate concept fostering translational medicine Floris A Valentijn, Michael Y Schakelaar, Maria A Hegeman, Willemijn D Schot, Wim J A G Dictus, Sandra Crnko, Toine Ten Broeke, Niels Bovenschen
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, 2023, vol. 52, p.198-209
Serpin B9 controls tumor cell killing by CAR T cells Thomas Kimman, Anne Slomp, Anne Martens, Sarah Grabherr, Shuang Li, Eline van Diest, Jan Meeldijk, Jurgen Kuball, Monique C. Minnema, Eric Eldering, Niels Bovenschen, Zsolt SebestyƩn, Victor Peperzak
Journal for ImmunoTherapy of Cancer, 2023, vol. 11
Temporal Dynamics of Serum Perforin and Granzymes in Three Different Clinical Stages of Virus-Induced Severe Fever with Thrombocytopenia Syndrome Sukhyun Ryu, Jin Kyeong Choi, Chiara Achangwa, Soojung Cho, Joo-Hee Hwang, Jeong-Hwan Hwang, Niels Bovenschen, Chang-Seop Lee
The American journal of tropical medicine and hygiene, 2023, vol. 109, p.554-558
Pediatric medulloblastoma express immune checkpoint B7-H3 S Li, G C Poolen, L C van Vliet, J G Schipper, R Broekhuizen, M Monnikhof, W Van Hecke, J F Vermeulen, N Bovenschen
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022, vol. 24, p.1204-1208
Strengthening educational leadership through a teaching-focused full professor career track Manon Kluijtmans, Niels Bovenschen, Christel Lutz, I. Meijerman, Veronique Schutjens, M.J. Van der Smagt, Leoniek Wijngaarts, F.J. Prins, Vincent Crone
Linked research hubs train students to tackle societal challenges Michael Y Schakelaar, Quique Bassat, Catherine M Comiskey, Katalin Felvinczi, Jan C M Haarhuis, Niels Bovenschen
Nature, 2022, vol. 611, p.449-449