Medema

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Recent publications

Perturbations in 3D genome organization can promote acquired drug resistance Anna G Manjón, Stefano Giustino Manzo, Stefan Prekovic, Leon Potgeter, Tom van Schaik, Ning Qing Liu, Koen Flach, Daniel Peric-Hupkes, Stacey Joosten, Hans Teunissen, Anoek Friskes, Mila Ilic, Dorine Hintzen, Vinícius H Franceschini-Santos, Wilbert Zwart, Elzo de Wit, Bas van Steensel, René H Medema
Cell Reports, 2023, vol. 42
Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity Claire Vennin, Chiara M. Cattaneo, Leontien Bosch, Serena Vegna, Xuhui Ma, Hugo G.J. Damstra, Moreno Martinovic, Efi Tsouri, Mila Ilic, Leyla Azarang, Jan R.T. van Weering, Emilia Pulver, Amber L. Zeeman, Tim Schelfhorst, Jeroen O. Lohuis, Anne C. Rios, Johanna F. Dekkers, Leila Akkari, Renee Menezes, Rene Medema, Serena R. Baglio, Anna Akhmanova, Sabine C. Linn, Simone Lemeer, Dirk M. Pegtel, Emile E. Voest, Jacco van Rheenen
Cancer Cell, 2023, vol. 41, p.1170-1185.e12
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer Stefan Prekovic, Karianne Schuurman, Isabel Mayayo-Peralta, Anna G Manjón, Mark Buijs, Selçuk Yavuz, Max D Wellenstein, Alejandro Barrera, Kim Monkhorst, Anne Huber, Ben Morris, Cor Lieftink, Theofilos Chalkiadakis, Ferhat Alkan, Joana Silva, Balázs Győrffy, Liesbeth Hoekman, Bram van den Broek, Hans Teunissen, Donna O Debets, Tesa Severson, Jos Jonkers, Timothy Reddy, Karin E de Visser, William Faller, Roderick Beijersbergen, Maarten Altelaar, Elzo de Wit, Rene Medema, Wilbert Zwart
Nature Communications, 2021, vol. 12, p.4360
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells Marten Hornsveld, Femke M. Feringa, Lenno Krenning, Jeroen van den Berg, Lydia M.M. Smits, Nguyen B.T. Nguyen, Maria J. Rodríguez-Colman, Tobias B. Dansen, René H. Medema, Boudewijn M.T. Burgering
Cell Reports, 2021, vol. 34
Degree and site of chromosomal instability define its oncogenic potential Wilma H.M. Hoevenaar, Aniek Janssen, Ajit I. Quirindongo, Huiying Ma, Sjoerd J. Klaasen, Antoinette Teixeira, Bastiaan van Gerwen, Nico Lansu, Folkert H.M. Morsink, G. Johan A. Offerhaus, René H. Medema, Geert J.P.L. Kops, Nannette Jelluma
Nature Communications, 2020, vol. 11
Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening Wienand A Omta, Roy G van Heesbeen, Ian Shen, Jacob de Nobel, Desmond Robers, Lieke M van der Velden, René H Medema, Arno P J M Siebes, Ad J Feelders, Sjaak Brinkkemper, Judith S Klumperman, Marco René Spruit, Matthieu J S Brinkhuis, David A Egan
SLAS discovery : advancing life sciences R & D, 2020, vol. 25, p.655-664