Marcel de Zoete

Associate Professor

Strategic program(s):

Contact

m.r.dezoete-2@umcutrecht.nl

Pure profile

Research groups

Inflammatory bowel diseases

Research aim

Our research is focused on the elucidation of the pathogenesis of Inflammatory bowel diseases (IBD), personalized medicine and on a severe complication of IBD: colitis-associated colorectal carcinoma.

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Microbial genomics and metagenomics

Research aim

We develop novel genomic methods for reconstructing and tracking antimicrobial resistance genes by building bioinformatics tools to facilitate data analysis of massive sequence data sets of pathogens and microbiomes.

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Molecular and cellular host-microbiota interactions

Research aim

Our research aims to unravel how the products from pathogenic and beneficial bacterial species within the intestinal microbiota contribute to human health and disease.

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Recent publications

All publications

Advanced Technologies for Studying Microbiome-Female Reproductive Tract Interactions Yosun A Kaya, Marcel R de Zoete, Gaby S Steba
Seminars in reproductive medicine, 2024, vol. 41, p.160-171

Dietary cystine restriction increases the proliferative capacity of the small intestine of mice Judith C.W. de Jong, Kristel S. van Rooijen, Edwin C.A. Stigter, M. Can Gülersönmez, Marcel R. de Zoete, Janetta Top, Matthijs J.D. Baars, Yvonne Vercoulen, Folkert Kuipers, Saskia W.C. Van Mil, Noortje Ijssennagger
PLoS ONE, 2024, vol. 19

Cohort profile of PLUTO Nikki de Mul, Diede Verlaan, Jelle P Ruurda, Wilhelmina M U van Grevenstein, Jeroen Hagendoorn, Gert-Jan de Borst, Menno R Vriens, Remco de Bree, Ronald P Zweemer, Charles Vogely, Jelle L G Haitsma Mulier, Lisette M Vernooij, Johannes B Reitsma, Marcel R de Zoete, Janetta Top, Jan A J Kluijtmans, Imo E Hoefer, Peter Noordzij, Thijs Rettig, Marije Marsman, Anne Marie G A de Smet, Lennie Derde, Judith van Waes, Mienke Rijsdijk, Willem Jan M Schellekens, Marc J M Bonten, Arjen J C Slooter, Olaf L Cremer
BMJ Open, 2023, vol. 13

Allobaculum mucilyticum sp. nov. and Allobaculum fili sp. nov., isolated from the human intestinal tract Guus H van Muijlwijk, Tyler A Rice, Richard A Flavell, Noah W Palm, Marcel R de Zoete
International journal of systemic and evolutionary microbiology, 2023, vol. 73

The Role of Microbiota-Derived Metabolites in Colorectal Cancer Coco Duizer, Marcel R de Zoete
International Journal of Molecular Sciences, 2023, vol. 24

Interspecies commensal interactions have nonlinear impacts on host immunity Tyler A Rice, Agata A Bielecka, Mytien T Nguyen, Connor E Rosen, Deguang Song, Nicole D Sonnert, Yi Yang, Yiyun Cao, Varnica Khetrapal, Jason R Catanzaro, Anjelica L Martin, Saleh A Rashed, Shana R Leopold, Liming Hao, Xuezhu Yu, David van Dijk, Aaron M Ring, Richard A Flavell, Marcel R de Zoete, Noah W Palm
Cell Host & Microbe, 2022, vol. 30, p.988-1002.e6