Profile photo Magdalena Lorenowicz

Magdalena Lorenowicz

Assistant Professor

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Biography

 Magdalena Lorenowicz studied Biotechnology at the Jagiellonian University in Kraków. In September 2001 she moved to Amsterdam to start her Ph.D. research. During her Ph.D. studies she investigated the role of cAMP signalling in the regulation of leukocyte chemotaxis and endothelial barrier function. After completion of her thesis, Magdalena moved to the Hubrecht Institute in Utrecht, where supported by prestigious VENI award (2008) she focused on the mechanism of Wnt secretion, combining the genetics of C. elegans with cutting edge cell biology techniques in mammalian cells. In April 2012 she joined the Department of Cell Biology and Center for Molecular Medicine at Universty Medical Center Utrecht to set up her own research line investigating molecular mechanisms regulating the immunosuppressive and regenerative properties of the human mesenchymal stem/stromal cells (MSC) with the ultimate goal to directly link her expertise in studying cell-cell communication with clinical applications. Since 2015 she works...

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Recent publications

Mesenchymal stromal/stem cells promote intestinal epithelium regeneration after chemotherapy-induced damage B. Yetkin-Arik, S. A. Jansen, S. Varderidou-Minasian, B. Westendorp, K. P. Skarp, M. Altelaar, C. A. Lindemans, M. J. Lorenowicz
Stem cell research & therapy, 2024, vol. 15
Minimal information for studies of extracellular vesicles (MISEV2023) Joshua A. Welsh, Deborah C.I. Goberdhan, Lorraine O’Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A.P. Driedonks, Uta Erdbrügger, Juan M. Falcon-Perez, Qing Ling Fu, Andrew F. Hill, Metka Lenassi, Sai Kiang Lim, G. Mahoney M˜y, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro...
Injectable hydrogels for sustained delivery of extracellular vesicles in cartilage regeneration Sanne M. van de Looij, Olivier G. de Jong, Tina Vermonden, Magdalena J. Lorenowicz
Journal of Controlled Release, 2023, vol. 355, p.685-708
Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model Kelly Warmink, Jaqueline L. Rios, Suzy Varderidou-Minasian, Marta Torres-Torrillas, Devin R. van Valkengoed, Sabine Versteeg, Niels Eijkelkamp, Harrie Weinans, Nicoline M. Korthagen, Magdalena J. Lorenowicz
Stem Cell Research and Therapy, 2023, vol. 14
A kaleidoscopic view of extracellular vesicles in lysosomal storage disorders Charlotte V. Hegeman, Olivier G. de Jong, Magdalena J. Lorenowicz
Extracellular Vesicles and Circulating Nucleic Acids, 2022, vol. 3, p.393-421
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, Iannis E Adamopoulos, Khosrow Adeli, Timon E Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat B Aggarwal, Maria Agnello, Patrizia Agostinis, Javed N...

Fellowships & Awards

2019        Grant from Dutch Paediatric Cancer Foundation (Kika); €125K

2018        - Personal grant from Dutch Arthritis Foundation (ReumaNederland); €150k

               - Personal grant from K.F. Hein Fonds/Utrechts Universiteitsfonds; €10K

2017    Translationeel Adult Stamcelonderzoek (TAS) Game changer grant from ZonMW; €400K; together with Dr. L. Vonk
       
2016    Young investigator...