Profile photo Maarten van Smeden

Maarten van Smeden

Associate Professor

Strategic program(s):

Biography

Maarten van Smeden is a medical statistician, associate professor of epidemiologic methods and head of the research program methodology at the Julius Center for Health Sciences and Primary Care, UMC Utrecht, the Netherlands. His research is focused on the development and evaluation of statistical and data science methodology, with a particular focus on methodology related to the development, validation and implementation of prediction models. 

Research groups

Methods for AI and data science

Research aim

To develop and validate methods for data science, AI, statistics and causal inference and to improve medical research and patient care through impactful applications and collaborations.

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Recent publications

Estimating diagnostic accuracy under uncertainty about disease status Kevin Jenniskens, Christiana A. Naaktgeboren, Jan Willem Uffen, Bas E. Kellerhuis, Maarten van Smeden, Karin H.A.H. Kaasjager, Jan Jelrik Oosterheert, Nandini Dendukuri, Johannes B. Reitsma
Journal of Clinical Epidemiology, 2026, vol. 195
Preliminary appraisal of machine learning–based prediction models Alex Carriero, Anne A.H. de Hond, Karel G.M. Moons, Maarten van Smeden
Journal of Clinical Epidemiology, 2026, vol. 194
Five tenets for advancing evidence-based precision medicine Daniel E. Coral, Jennifer L. Sargent, Julia Carrasco-Zanini, Luis M. Coral, Aaron J. Deutsch, Miriam S. Udler, Giuseppe N. Giordano, Guillaume Pare, Ewan R. Pearson, Maarten van Smeden, Paul W. Franks
Nature medicine, 2026, vol. 32, p.1211-1222
Signal or noise? Evaluating commonly used attribution methods for explaining deep neural networks in electrocardiogram classification Bauke K.O. Arends, Wouter A.C. van Amsterdam, Pim van der Harst, Maarten van Smeden, René van Es, Rutger R. van de Leur
European Heart Journal - Digital Health, 2026, vol. 7
Prediction models developed using artificial intelligence Maerziya Yusufujiang, Constanza L Andaur Navarro, Johanna Aa Damen, Toshihiko Takada, Geert-Jan Geersing, Lotty Hooft, Ewoud Schuit, Karel Gm Moons, Valentijn Mt de Jong, Maarten van Smeden
Diagnostic and Prognostic Research, 2026, vol. 10
LAD Ruurd J.A. Kuiper, Lars de Groot, Bram van Es, Maarten van Smeden, Ayoub Bagheri
2025, p.97-110