Profile photo Maarten Smits

Maarten Smits

Associate Professor - medical

Strategic program(s):

Biography

Maarten Smits is an associate professor, clinical scientist and interventional radiologist at UMC Utrecht, specializing in interventional oncology and minimally invasive, image-guided treatments for cancer patients. Appointed as Clinical Scientist in 2025, he has founded and leads the UMC Utrecht Interventional Oncology Research Team. Under his leadership, the team has expanded to 19 members, including PhD students and postdocs, and is participating in several EU-funded consortia.

His clinical and research focus lies in two domains: ablation and radioembolization. In ablation, he pioneered the Hepatic Arteriography and C-arm CT Guided Ablation (HepACAGA) technique for treating liver tumors. Since 2021, HepACAGA has become the standard method at UMC Utrecht, achieving significantly improved patient outcomes compared to conventional approaches. Its success has led to global adoption in more than 20 centers, with ongoing multicenter studies further validating its effectiveness.

In radioembolization, UMC Utrecht is internationally recognized for its groundbreaking work with holmium microspheres. Having contributed to pivotal studies such as HEPAR, SIM, and CAIRO7, Maarten now focuses on advancing tumor selectivity and simplifying treatment pathways.

His collaborations with industry partners—including Philips, Terumo, Medtronic, and Boston Scientific—have translated innovations from the lab into practice, ensuring access to cutting-edge treatments.

Beyond his research, Maarten plays a key role in medical education as Program Director for Interventional Radiology training at UMC Utrecht. He supervises PhD candidates, residents, and fellows, fostering a culture where collaboration, innovation, and learning from experience are central.

His academic contributions include more than 80 peer-reviewed publications, textbook chapters, and multiple international lectures at leading conferences such as CIRSE and ECIO. He serves on the editorial board of Cardiovascular and Interventional Radiology (CVIR) and contributes to national and international guideline development.

Through his leadership, research, and dedication to innovation, Maarten is helping shape the future of interventional oncology, with the vision of treating more patients effectively, sustainably, and with fewer resources—ultimately improving outcomes and quality of life for people living with cancer.

 

Grants and awards:

  • Horizon Europe IHI – PreciseOnco
  • Horizon Europe IHI – SHERPA
  • Horizon Europe IHI – IMAGIO
  • ZonMW Veelbelovende Zorg – CAIRO7
  • SKMS – Kwaliteitsnormen Interventieradiologie
  • KWF – Holmium radioembolization in HCC patients
  • Woldringprijs – Dutch Society for Nuclear Medicine
  • Fellowship Clinical Research Talent – UMC Utrecht
  • Alexander Suerman Stipendium – UMC Utrecht

Strategic program(s):

Contact

Research groups

Interventional oncology research group

Research aim

Interventional oncology is a fast-moving subspeciality providing image-guided treatment of cancer by interventional radiologists. Our aim is to help develop, evaluate and implement innovations in this field.

Go to group

Primary Liver Tumors research group

Research aim

To improve surveillance, diagnostics, treatment, and outcome for patients with primary liver tumors (hepatocellular carcinoma and cholangiocarcinoma) by interdisciplinary and (inter-)national collaborative research

Go to group

Recent publications

Radioembolization Practice in North America Versus Europe Grace Keane, Marnix G.E.H. Lam, Arthur J.A.T. Braat, Rutger C.G. Bruijnen, Nathalie Kaufmann, Hugo W.A.M. de Jong, Riad Salem, Maarten L.J. Smits
Current Oncology, 2026, vol. 33
Portal vein embolization versus radiation lobectomy as pre-treatment for major liver resection for colorectal liver metastases Khalil Ramdhani, Rosalie C M van Rees, Daan Andel, Jeanine M L Roodhart, Arthur J A T Braat, Rutger C G Bruijnen, Inne H M Borel Rinkes, Onno Kranenburg, Marnix G E H Lam, Maarten L J Smits, Jeroen Hagendoorn
Angiogenesis, 2026, vol. 29
International multisociety Delphi consensus for liver tumour thermal ablation Iwan Paolucci, Christiaan G Overduin, Edward W Johnston, Gregor Laimer, Muneeb Ahmed, Ronald S Arellano, Marie Beerman, Lukas P Beyer, David J Breen, Mark C Burgmans, Marco Calandri, Ming-Chih Chern, Laura Crocetti, Ronald M van Dam, Alban Denys, Bjørn Edwin, Dimitrios Filippiadis, Yuman Fong, Nicos Fotiadis, Jacob Freedman, Åsmund A Fretland, Mariano Gimenez, Rodrigo G Garcia, Rosario F Grasso, Thomas K Helmberger, Pim Hendriks, Roberto Iezzi, Sjoerd Fm Jenniskens, Alexander Kupferthaler, Anja Lachenmayer, Fred T Lee, Jeong M Lee, Susan van der Lei, Christiaan van der Leij, Ping Liang, Charles C-W Lin, Lukas Luerken, Manuel Maglione, Andreas Mahnken, Justin P McWilliams, Marcos Menezes, Govindarajan Narayanan, Franco Orsi, Philippe L Pereira, Uei Pua, Robbert S Puijk, Hyunchul Rhim, William S Rilling, Simeon J S Ruiter, Anthony G Ryan, Peter Schullian, Paul B Shyn, Ajith K Siriwardena, Maarten L J Smits, Constantinos T Sofocleous, Luigi Solbiati, Vlasios Sotirchos, Stefan Stättner, Marco van Strijen, Trygve Syversveen, Pascale Tinguely, Lambros Tselikas, Jean-Nicolas Vauthey, Thomas J Vogl, Tze M Wah, Sarah B White, Philipp Wiggermann, Bradford J Wood, Jan van der Meulen, S Nahum Goldberg, Martijn R Meijerink, Reto Bale, Bruno C Odisio
The Lancet Oncology, 2026, vol. 27, p.e248-e258
International multisociety Delphi consensus for liver tumour thermal ablation Gregor Laimer, Edward W Johnston, Christiaan G Overduin, Iwan Paolucci, Muneeb Ahmed, Ronald S Arellano, Marie Beermann, Lukas P Beyer, David J Breen, Mark C Burgmans, Marco Calandri, Ming-Chih Chern, Laura Crocetti, Ronald M van Dam, Alban Denys, Bjørn Edwin, Dimitrios Filippiadis, Yuman Fong, Nicos Fotiadis, Jacob Freedman, Åsmund A Fretland, Mariano Gimenez, Rodrigo G Garcia, Rosario F Grasso, Thomas K Helmberger, Pim Hendriks, Roberto Iezzi, Sjoerd Fm Jenniskens, Alexander Kupferthaler, Anja Lachenmayer, Fred T Lee, Jeong M Lee, Susan van der Lei, Christiaan van der Leij, Ping Liang, Charles C-W Lin, Lukas Luerken, Manuel Maglione, Andreas Mahnken, Justin P McWilliams, Marcos Menezes, Govindarajan Narayanan, Franco Orsi, Philippe L Pereira, Uei Pua, Robbert S Puijk, Hyunchul Rhim, William S Rilling, Simeon J S Ruiter, Anthony G Ryan, Peter Schullian, Paul B Shyn, Ajith K Siriwardena, Maarten L J Smits, Constantinos T Sofocleous, Luigi Solbiati, Vlasios Sotirchos, Stefan Stättner, Marco van Strijen, Trygve Syversveen, Pascale Tinguely, Lambros Tselikas, Jean-Nicolas Vauthey, Thomas J Vogl, Tze M Wah, Sarah B White, Philipp Wiggermann, Bradford J Wood, Jan van der Meulen, S Nahum Goldberg, Martijn R Meijerink, Bruno C Odisio, Reto Bale
The Lancet Oncology, 2026, vol. 27, p.e259-e270
Severe Complication of Thermal Ablation of a Liver Tumor Khalil Ramdhani, Niek Wijnen, Rekha A.A. Mungra, Maarten L.J. Smits
Cardiovascular and Interventional Radiology, 2026, vol. 49, p.1047–1050
ESR Innovation in Focus Stavros Spiliopoulos, Lorenzo Patrone, Maarten Smits, Marco van Strijen, Pierleone Lucatelli
European Radiology, 2026, vol. 36, p.4324–4326