Lotty Hooft

Full Professor

Biography

Prof. Dr. Lotty Hooft is Professor of Evidence Synthesis and Knowledge Translation in Healthcare at the Julius Center, UMC Utrecht, and Director of Cochrane Netherlands. She heads the Department of Epidemiology and Health Economics and the international MSc in Epidemiology program. With more than two decades of experience, she is an internationally recognized expert in systematic reviews, diagnostic and prognostic test evaluation, and guideline development, and has helped shape key reporting and risk-of-bias standards including TRIPOD, STARD, and PROBAST, as well as the (de)implementation of evidence-based healthcare practices.

Contact

lhooft@umcutrecht.nl

Pure profile

Recent publications

All publications

Pretrained language models for selection of cohorts from electronic health records I. Spiero, J. A.A. Damen, L. Hooft, K. G.M. Moons, A. M. Leeuwenberg
Informatics in Medicine Unlocked, 2026, vol. 65

Macroscopic prediction of cervical dysplasia at colposcopy for see-and-treat patient selection Johanna A A Damen, Jacob Pieter Hoogendam, Demy L Idema, Marle E Lokerse, Pauline Heus, Kevin Jenniskens, Isabelle M L P Kamm, Marissa J M Traets, René Spijker, Ronald Zweemer, Lotty Hooft
European Journal of Obstetrics, Gynecology and Reproductive Biology, 2026, vol. 325

Towards responsible digital health implementation Bazuin Tom, Michiel Sebastiaan Oerbekke, Pauline Heus, Mike Petrus Theodora Kusters, Dave Anton Dongelmans, Annelies Visser, Arie Franx, Johann Klaus Götz Wietasch, Lotty Hooft, Maarten Jurriaan van der Laan
Digital health, 2026, vol. 12, p.1-14

Cost-Effectiveness of Pharmacologic Treatments in Adults With Overweight or Obesity Kevin Jenniskens, Linde F Huis In 't Veld, Marle E Lokerse, Demy L Idema, Mike P T Kusters, Kim van der Braak, Rene Spijker, Robin W M Vernooij, Michiel S Oerbekke, Lotty Hooft, Johanna A A Damen
Annals of Internal Medicine, 2026, vol. 179, p.1156-1168

Benefits and Harms of Pharmacologic Treatments in Adults With Overweight or Obesity Johanna A A Damen, Demy L Idema, Robin W M Vernooij, Linde F Huis In 't Veld, Mike P T Kusters, Marle E Lokerse, Emilie de Kanter, Rene Spijker, Kim van der Braak, Kevin Jenniskens, Michiel S Oerbekke, Lotty Hooft
Annals of Internal Medicine, 2026, vol. 179, p.1140-1155

Comparison of local large language models for extraction of signs and symptoms data from electronic health records Isa Spiero, Merijn H Rijk, Matthew A Scheeres, Frans H Rutten, Geert-Jan Geersing, Tamara N Platteel, Karel G M Moons, Lotty Hooft, Johanna A A Damen, Roderick P Venekamp, Artuur M Leeuwenberg
PLoS ONE, 2026, vol. 21

External positions

Lid ZEGG evaluatiecommissie (Zorg Evaluatie en Gepast Gebruik) - Evaluatie van ZEGG aanvragen vanuit UMC perspectief - ZonMW/ZIN

Lid Wetenschappelijke Adviesraad (WAR) Care & Cure - Adviseren en beoordelen van duidingsrapporten - Zorginstituut Nederland

Lid van onafhankelijke adviescommissie - Toetsen van projectideeën en uitgewerkte subsidieaanvragen voor de subsidieregeling (Advenzo) - Zorginstituut

Alternate membership Veelbelovende Zorg - Adviseren over methodologie in co-creaties - ZonMW/ZIN

Member Steering Group Scientific Committee ICTRP (WHO) - Wetenschappelijke koers voor internationale trial-registratie en datatransparantie mede vormgeven - WHO

WHO Essential Diagnostic List (EDL) Evidence Submission Methodological Reviewer - Toetsen van de methodologisch de bewijsvoering voor de wereldwijde lijst van essentiële diagnostiek - WHO

Member Editorial Board Journal for Diagnostic and Prognostic Research. - Redacteurschap om de wetenschappelijke kwaliteit van publicaties te bewaken - Journal for Diagnostic and Prognostic Research

Member Council and Methods Groups (Prognosis, Screening and Diagnostic Tests) - Methodology development - Cochrane

Member WHO International Clinical Trial Registry Platform (ICTRP) Scientific Advisory Group. - Adviesrol die wereldwijd bijdraagt aan de transparantie en registratie van klinische onderzoek - WHO