Lieza Exalto

Assistant Professor - medical

Biography

Lieza Exalto, is a neurologist who has received her medical training in the UMC Utrecht. In 2014 she obtained her PhD degree with the thesis “Diabetes and Dementia, the bitter taste of a sweet disease”. Afterwards she continued her research in the Vascular Cognitive Impairment group of prof. Biessels and introduced sex and gender differences as relevant research topic. Lieza received funding from Alzheimer Nederland for her project “Does sex modulate the phenotype and prognosis of vascular cognitive impairment”.

 

Lieza is work-package leader “sex differences” in the Dutch Heart-Brain Consortium study. She collaborates with the META-VCI MAP consortium on research projects on sex differences in post-stroke cognitive impairment. In the European multicenter H2020 study RECOGNISED, she is work-package leader of the cognitive testing. In February 2020 she received the prize for best integration of sex and gender considerations in cardiovascular research plans, during the Libin International Trainee Symposium: Research is Better with Sex and Gender! 

Recent publications

Sex differences in documented clinical features of memory clinic patients Sanne Kuipers, L Malin Overmars, Bram van Es, Sander C Tan, Jet M J Vonk, Majon Muller, Mark C H de Groot, Wouter W van Solinge, Saskia Haitjema, Michiel L Bots, Geert Jan Biessels, Lieza G Exalto
Cerebral Circulation - Cognition and Behavior, 2026, vol. 10
Testing the use of retinal microvascular parameters to identify individuals with type 2 diabetes with mild cognitive impairment Frederik N. Pedersen, Noemi Lois, Geert Jan Biessels, Lieza Exalto, Santiago Perez-Hoyos, Rafael Simó, Jakob Grauslund
Primary Care Diabetes, 2026, vol. 20, p.197-202
Relationship between retinal neurodysfunction and cognitive impairment in type 2 diabetes Rafael Simó, Cristina Hernández, Simona Frontoni, Paolo Sbraccia, Reinier Schlingemann, Xavier Valldeperas, Stela Vujosevic, Inês Marques, José Cunha-Vaz, Jakob Grauslund, Frederik N Pedersen, María-José Barahona, Natasa Popovic, Gianpaolo Zerbini, Andreea Ciudin, Santiago Perez-Hoyos, Lieza Exalto, Geert Jan Biessels, Noemi Lois
Diabetologia, 2026, vol. 69, p.1337-1353
Comment by European Alzheimer's Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer' s disease Frank Jessen, Javier Arbizu, Mercé Boada, Mircea Balasa, Karim Bennys, Marina Boban, Katharina Bürger, Andrea Chincarini, Annachiara Cagnin, Peter Paul De Deyn, Emrah Düzel, Sebastiaan Engelborghs, Michael Ewers, Lieza G Exalto, Wiesje M van der Flier, Juan Fortea, Kristian Steen Frederiksen, Giovanni B Frisoni, Lutz Frölich, Alejandro J Garza-Martinez, Timo Grimmer, Bernard Hanseeuw, Jakub Hort, Adrian Ivanoiu, Patrick G Kehoe, Sean P Kennelly, Silke Kern, Stefan Klöppel, Lenka Krajčovičová, Milica G Kramberger, Bernadette McGuinness, Patrizia Mecocci, Timo Jan Oberstein, Pierre-Jean Ousset, Claire Paquet, Robert Perneczky, Fabrizio Piazza, Domenico Plantone, Innocenzo Rainero, Guillaume Sacco, Eric Salmon, Isabel Santana, Nikolaos Scarmeas, Anja Schneider, Jonathan M Schott, Eino Solje, Elka Stefanova, Elisabeth Stögmann, Mélanie Strauss, Stanislav Sutovsky, Gunhild Waldemar, Bengt Winblad
Journal of Prevention of Alzheimer's Disease, 2025, vol. 12, p.100259
Association between retinal microvasculature and cerebral small vessel function in type 2 diabetes Jan F de Leijer, Stanley D T Pham, Tessa A C M Vissers, Lieza G Exalto, Reinier O Schlingemann, Jeroen S W Siero, Jaco J M Zwanenburg, Rafael Simó, Noemi Lois, Thomas T van Sloten, Geert Jan Biessels,
Diabetes, Obesity & Metabolism, 2025, vol. 27, p.5346-5350
Revisiting the Montreal Cognitive Assessment in a European cohort of elderly living with type 2 diabetes Natasa Popovic, Noemi Lois, Santiago Pérez-Hoyos, Rafael Simó, Lieza G Exalto,
Journal of Alzheimer's disease : JAD, 2025, vol. 104, p.585-594