Lennie Derde

Assistant Professor - medical

Strategic program(s):

Biography

Lennie is an ICU consultant in the UMC Utrecht, with a background in infectious diseases and epidemiology. She co-leads (with Olaf Cremer) the "epidemiology of sepsis and inflammation" research group. Her research focuses on clinical trials in critically ill patients, especially those with sepsis and severe infections, to improve trial methodology/design, delivery, and analysis. Lennie is the European PI and immediate past global chair of REMAP-CAP, and a co-applicant and work package leader on EU-funded projects like RECOVER and ECRAID-Base, leads the ZonMw funded IMPRINT consortium and is co-applicant on several international collaborative grants. She is a member of the Steering Committee for the Surviving Sepsis Campaign and the ISAB of Sepsis Canada.

Strategic program(s):

Contact

lderde@umcutrecht.nl

Pure profile

Research groups

Epidemiology and clinical trials in infectious diseases

Research aim

To improve prevention, diagnosis and treatment of infectious diseases and to establish an international research infrastructure for a rapid scientific response in the face of a new infectious disease threat.

Go to group

Epidemiology of sepsis & inflammation in critically ill patients

Research aim

We design and conduct clinical epidemiological research focused on risk stratification, early diagnosis, and novel treatment of critically ill patients with severe infections.

Go to group

Recent publications

All publications

Think beyond the standard Luis Felipe Reyes, Andrew Conway Morris, Cristian Serrano-Mayorga, Lennie P G Derde, Robert P Dickson, Ignacio Martin-Loeches
Lancet (London, England), 2026, vol. 407, p.1231-1232

Executive Summary Hallie C Prescott, Massimo Antonelli, Waleed Alhazzani, Morten Hylander Møller, Fayez Alshamsi, Luciano C P Azevedo, Emilie Belley-Cote, Jan De Waele, Lennie Derde, Joanna C Dionne, Laura Evans, Hayley B Gershengorn, Carol L Hodgson, Kimia Honarmand, Jozef Kesecioglu, Lauralyn McIntyre, Mervyn Mer, Mark E Nunnally, Simon J W Oczkowski, Bram Rochwerg, Olurotimi Olaolu Akinola, Kwame A Akuamoah-Boateng, Laura Alberto, Derek C Angus, Yaseen M Arabi, Elie Azoulay, Maurizio Cecconi, Pauline F Convocar, Gennaro De Pascale, Kent Doi, Bin Du, Moritoki Egi, Marie-Carmelle Elie-Turenne, Ricard Ferrer, Alison Fox-Robichaud, Craig French, Yonathan Freund, Michelle Ng Gong, Caleb P Hale, Naomi E Hammond, Madiha Hashmi, Leo Heunks, Theodore J Iwashyna, Shevin T Jacob, Michael Klompas, Arthur Kwizera, Murdoch Leeies, Joanna D Lejnieks, Mitchell M Levy, Flavia R Machado, Marcelo O Maia, Henry Masur, Ryan C Maves, Steven McGloughlin, Joanne McPeake, Nicholas M Mohr, Sheila Nainan Myatra, Marlies Ostermann, Sandra L Peake, Mathias W Pletz, Jason A Roberts, Regis G Rosa, Robert G Sawyer, Christa A Schorr, Steven Q Simpson, Li Weng, W Joost Wiersinga, Andrew Rhodes, Craig M Coopersmith
Critical care medicine, 2026, vol. 54, p.715-724

Surviving Sepsis Campaign Hallie C Prescott, Massimo Antonelli, Waleed Alhazzani, Morten Hylander Møller, Fayez Alshamsi, Luciano C P Azevedo, Emilie Belley-Cote, Jan De Waele, Lennie Derde, Joanna C Dionne, Laura Evans, Hayley B Gershengorn, Carol L Hodgson, Kimia Honarmand, Jozef Kesecioglu, Lauralyn McIntyre, Mervyn Mer, Mark E Nunnally, Simon J W Oczkowski, Bram Rochwerg, Olurotimi Olaolu Akinola, Kwame A Akuamoah-Boateng, Laura Alberto, Derek C Angus, Yaseen M Arabi, Elie Azoulay, Maurizio Cecconi, Pauline F Convocar, Gennaro De Pascale, Kent Doi, Bin Du, Moritoki Egi, Marie-Carmelle Elie-Turenne, Ricard Ferrer, Alison Fox-Robichaud, Craig French, Yonathan Freund, Michelle Ng Gong, Caleb P Hale, Naomi E Hammond, Madiha Hashmi, Leo Heunks, Theodore J Iwashyna, Shevin T Jacob, Michael Klompas, Arthur Kwizera, Murdoch Leeies, Joanna D Lejnieks, Mitchell M Levy, Flavia R Machado, Marcelo O Maia, Henry Masur, Ryan C Maves, Steven McGloughlin, Joanne McPeake, Nicholas M Mohr, Sheila Nainan Myatra, Marlies Ostermann, Sandra L Peake, Mathias W Pletz, Jason A Roberts, Regis G Rosa, Robert G Sawyer, Christa A Schorr, Steven Q Simpson, Li Weng, W Joost Wiersinga, Andrew Rhodes, Craig M Coopersmith
Critical care medicine, 2026, vol. 54, p.725-812

11 - Trials Simon Finfer, Lennie P.G. Derde, Naomi E. Hammond, Anthony Delaney
2026, p.89-98

Temporal robustness of biomarker-based classification algorithms for sepsis Emma Rademaker, Rombout B E van Amstel, Said El Bouhaddani, Marc J M Bonten, Lennie P G Derde, Lonneke van Vught, Tom van der Poll, Lieuwe D J Bos, Harm-Jan de Grooth, Olaf L Cremer
Intensive Care Medicine, 2025, vol. 52, p.22-30

Community-acquired pneumonia Luis Felipe Reyes, Andrew Conway Morris, Cristian Serrano-Mayorga, Lennie P G Derde, Robert P Dickson, Ignacio Martin-Loeches
Lancet (London, England), 2025, vol. 406, p.2371-2388

External positions

CEO - Chief Executive Officer - Ecraid

lid Steering Committee en lid Guidelines (als ESICM Vice-chair) - Maken internationale sepsis richtlijn, en als Steering Committee strategische richting bepalen. - Surviving Sepsis Campaign

Lid International Scientific Advisory Board - Advies geven aan deze not-for-profit organisatie ter verbetering uitkomsten van sepsis - Sepsis Canada