Jurgen Kuball

Full Professor

Strategic program(s):

Biography

Prof. Dr. Jürgen Kuball is Chair of the Department of Hematology, and Director of the Bone Marrow Transplantation Program at the UMC Utrecht Cancer Centre. His research activities focus on tumor immunology and the ATMP development of a next generation of engineered immune cells, with an emphasis on the therapeutic potential of individual receptors derived from γδT cells. His clinical activities focus around acute leukemia and allogeneic stem cell transplantation. He is an active member of European Society for Blood and Marrow Transplantation (EBMT), and has chaired the Legal Regulatory Affairs Committee of the EBMT since 2019.

Dr. Kuball received his medical degree in Hematology at the University of Mainz, Germany, and completed his post-doctoral fellowship at the Fred Hutchinson Cancer Center in Seattle, WA, USA. He joined the Department of Hematology at the UMC Utrecht in 2007 as a hematologist and immunologist. In 2010, he became a VIDI-laureate, and the chair of the Applied & Tumor-Immunology section within the Laboratory of Translation Immunology. He has chaired the Department of Hematology (adults) since 2013.

For more information on experimental and translational research please visit Kuball Laboratories

Strategic program(s):

Contact

jkuball@umcutrecht.nl

Pure profile

Research groups

Tumor Immunology

Research aim

Our research aims to revolutionise cancer treatment by advancing innovative immunotherapies, ensuring safer, more effective therapies, and improving patient outcomes, ultimately transforming lives through cutting-edge translational cancer research.

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Recent publications

All publications

Virtual twins for personalised CAR T-cell therapy in myeloma Kristin Reiche, Ulrike Weirauch, Markus Kreuz, Luise Fischer, Luuk Gras, Thomas Neumuth, Uwe Platzbecker, Ulrike Köhl, Regina Demlova, Andreas Kremer, Holger Fröhlich, Stefan Franke, Maximilian Merz, , Jurgen Kuball
The Lancet. Haematology, 2025, vol. 12, p.e490-e491

Autologous profiling reveals inter-patient heterogeneity in Vδ2 +γδTIL responses to glioblastoma driven by extracellular matrix-BTN3A axis. Mara J T Nicolasen, Lucrezia Cde Gatti, Laia Gasull-Celades, Peter Brazda, Marta Botas, Daniel Zawal, Esmee J van Vliet, Astrid Cleven, Zsolt Sebestyén, Pierre A Robe, Dennis X Beringer, Jurgen Kuball
Journal for immunotherapy of cancer, 2025, vol. 13

Posttransplant cells for the win? Pleun Schonewille, Anna van Rhenen, Renske MT ten Ham, Moniek de Witte, Jürgen Kuball
Hematology. American Society of Hematology. Education Program, 2025, vol. 2025, p.537-546

Operational burden and fragmented implementation in CAR T-cell therapy Nick van Sinderen, Julie Dolva, Caterina Riillo, Raquel Espada, Christof Scheid, Suzanne van Dorp, Marten Nijziel, Margot Jak, Florent Malard, Christian Chabannon, Andrea Egan, Chiara Bonini, Julio Delgado, Martin Dreyling, Annalisa Ruggeri, Marion Subklewe, Anna Sureda, Yolanda Cabrerizo, Ibrahim Yakoub-Agha, Tuula Rintala, Lynn Manson, Laurel Anderson, Olivier Urbain, Rachel Luke, Lea Brandt Kristensen, Anne Emmett, Jürgen Kuball
Hemasphere, 2025, vol. 9

Pure white cell aplasia following allogeneic hematopoietic stem cell transplantation Laura A Michielsen, Moniek A de Witte, Laura G M Daenen, Anke Janssen, Roos J Leguit, Jürgen Kuball, Anna van Rhenen
Bone Marrow Transplantation, 2025, vol. 60, p.1669-1671

Impact of the addition of antithymocyte globulin to post-transplantation cyclophosphamide in haploidentical transplantation with peripheral blood compared to post-transplantation cyclophosphamide alone Antoine Capes, Jarl E Mooyaart, Didier Blaise, Stefania Bramanti, Mi Kwon, Mohamad Mohty, Patrice Chevallier, Jan Vydra, Péter Reményi, Edouard Forcade, Lucía López Corral, Maija Itälä-Remes, Ali Bazarbachi, Enrico Derenzini, Jorinde D Hoogenboom, Jürgen Kuball, Giorgia Battipaglia, Florent Malard, Annalisa Ruggeri
British Journal of Haematology, 2025, vol. 207, p.1529-1537

Fellowships & Awards

American Association of Cancer Research-GlaxoSmithKline Scholar in Cancer Research Award (2001)
Stipendiat der Deutschen Krebshilfe (2005-2007)
Team Science recognition award of the „Society for Immunotherapy of Cancer“ to Jürgen Kuball and the University of Washington, USA (2010)
VIDI-Laureate ZonMW, The Netherlands (2010)

External positions

aandeelhouder - shareholder via Gadeta Founders - Century Therapeutics & Adeta

Chair - Chairing - Immunology Community Life Science

Secretary team member - bestuurslid - GoCART Coalition (EBMT/EHA)

Inkomsten licentie - Onderzoek - UMCU Holding

Commissie lid PPS commissie - grant indieningen voor KWF beoordelen - KWF

aandeelhouder - Receiving revenues from licensed patents via UMCU - UMC Holding

Chair legal and rgulatory affairs committee - Chair - EBMT

grant - grant ontvangen voor onderzoek - Novartis

Onderzoeker - grant ontvangen voor onderzoek - Miltenyi

bestuurslid - member general Board - HOVON

Patent holder multipe inventions licensed to Gadeta-follow up company Century Therapeuitcs &Miltenyi - Patent houder - Various