Profile photo Arjen Koppen

Arjen Koppen

Assistant Professor

Strategic program(s):

Biography

Arjen Koppen obtained his master in Chemistry, with a specialization in Biochemistry, at the faculty of Chemistry of the University of Amsterdam. He obtained is PhD at the faculty of Medicine of the University of Amsterdam. His PhD research focused on the transcriptional regulation of potential oncogenes and tumor suppressor genes by the oncogene N-MYC in neuroblastoma. Following his PhD, he became a postdoctoral researcher in the department of Metabolic Diseases in the UMC Utrecht, investigating gene regulation by the nuclear receptor PPAR-γ in adipocytes. During this period, he secured a permanent research position.

In 2013, Arjen transitioned to clinical toxicology and joined the Dutch Poisons Information Center (DPIC). In 2021, he became a European Registered Toxicologist, and in 2026 he qualified as an Health Advisor for Hazardous Substances (GAGS, East Netherlands region). Within the DPIC, Arjen is an expert in (1) the toxicology of industrial and household products, (2) paracetamol toxicology, and (3) deliberate self-poisonings.

Recent publications

Methotrexate toxicity and glucarpidase Arjen Koppen, Maaike A. Sikma, Frederike K. Engels, Marise R. Heerma van Voss, Martine E.D. Chamuleau, Imke H. Bartelink, Marieke A. Dijkman
British Journal of Clinical Pharmacology, 2025, vol. 91, p.1289-1292
Poison Center Surveillance of Occupational Incidents with Hazardous Materials (2016-2023) Anja P G Wijnands, Arjen Koppen, Irma de Vries, Dylan W de Lange, Saskia J Rietjens
International journal of environmental research and public health, 2025, vol. 22
Risk factors for deliberate self-poisoning among children and adolescents in The Netherlands Ilze M J Thoonen, Saskia J Rietjens, Agnes G van Velzen, Dylan W de Lange, Arjen Koppen
Clinical Toxicology , 2024, vol. 62, p.39-45
Clinical toxicology of exposures to chemicals from clandestine drug laboratories Arjen Koppen, Anja P G Wijnands-Kleukers, Femke M J Gresnigt, Dylan W de Lange
Clinical Toxicology , 2022, vol. 60, p.559-570
The relation between body iron stores and adipose tissue function in patients with manifest vascular disease J. Westerink, J. Olijhoek, A. Koppen, D.R. Faber, E. Kalkhoven, H. Monajemi, B.S. van Asbeck, Y. van der Graaf, F.L.J. Visseren
European Journal of Clinical Investigation, 2013, vol. 43, p.1240-1249
A novel RNAi lethality rescue screen to identify regulators of adipogenesis P.O van Beekum, Y. Gao, R. Berger, A. Koppen, E. Kalkhoven
PLoS ONE [E], 2012, vol. 7, p.e37680

External positions

Algemeen bestuur EAPCCT - Bijdrage beleid, strategie EAPCCT en organisatie wetenschappelijk congres - EAPCCT

Gezondheidskundig Adviseur Gevaarlijke Stoffen - Piketfunctie binnen de GGD/GHOR; advieseursfunctie bij incidenten met gevaarlijke stoffen - GGD