Profile photo Edward Knol

Edward Knol

Associate Professor

Strategic program(s):

Biography

Edward Knol is a biomedical scientist and immunologist in the departments of Immunology and Dermatology/Allergology at the University Medical Center Utrecht. He did his PhD training in the Blood Transfusion Service of the University of Amsterdam and had a postdoc position at Johns Hopkins University in Baltimore. His scientific research focuses on allergic diseases, in particularly eczema and food allergy. The research focusses on 1) improved insights in pathomechanisms, 2) explore new treatment options, 3) improve current diagnostics and establish new diagnostics platforms. In his career Edward Knol discovered CD63 as the basophil activation marker, described the important role of the peanut allergen Ara h 2 and described A20/TNFAIP3 dysregulation in atopic dermatitis. He is involved in several (inter)national collaborations and is Secretary General of the Dutch Society of Immunology (~1400 members).

Within the University Medical Center he holds a teaching position and chairs the education committee of the University Utrecht graduate school Immunity and Infection (50 master and 170 PhD students). He is coordinator and examiner of: 1) Course Clinical Immunology for 3rd years students Biomedical Sciences, 2) Course Immune Therapy for 2nd years student Medicine and 3) Course Infection and Immunity for 3rd years Students at the Technical University Eindhoven. 

At the international level Edward Knol has organised 3 European Academy of Allergy and Clinical Immunology (EAACI) Winter schools and was the chair of the Scientific Program Committee of the EAACI annual meetings in 2014-2016. In addition, since 2019 he is Vice President Congresses of EAACI. 

Specialties: Immunology, Allergy, Food Allergy, Atopic Dermatitis, Basophilic granulocytes, T lymphocytes, allergy diagnostic tests, basophil activation test

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=Knol%20EF%5BAuthor%5D&cauthor=true&cauthor_uid=26198455

 

Google Scholar:  http://scholar.google.com/citations?hl=en&user=nfo_25cAAAAJ

Scopus H-factor: h-index: 66

Research gate: h-index: 73, : RG score: 9,612

Google Scholar: h-index: 79 

 

Recent publications

Diagnosis of primary CNS lymphoma through molecular and immune biomarkers in cerebrospinal fluid (PRICELUS) Josephus L M van Rooij, Peter H Wessels, Johanna M Niers, Jacoline E C Bromberg, Johanna M M Gijtenbeek, Rick van Haastert, Henk J T Ruven, Bob Meek, Marcel M Verbeek, Nienke Solleveld-Westerink, Wendy W J de Leng, Angelika Mühlebner, Anton W Langerak, Sharon Berendsen, Edward F Knol, Hanna van Alkemade, Tatjana Seute, Monique C Minnema, Stefan Nierkens, Tom J Snijders
The Lancet. Haematology, 2026, vol. 13, p.e376-e385
Exercise affects systemic basophil responses in humans T. C. Pelgrim, B. N. Jukema, L. Koopmans, C. C.W.G. Bongers, M. T.E. Hopman, E. F. Knol, N. Vrisekoop, L. Koenderman
Cytometry Part B - Clinical Cytometry, 2026, vol. 110, p.92-101
Diagnosing IgE-mediated food allergy Carina Venter, Susanne Halken, Alice Toniolo, Anna Nowak-Wegrzyn, Berber Vlieg-Boerstra, Caroline A. Nilsson, David M. Fleischer, Debra de Silva, Domingo Barber, Ekaterina Khaleva, Edward Knol, Jennifer L.P. Protudjer, Laura Morandini, Antonella Muraro,
Journal of Allergy and Clinical Immunology: Global, 2025, vol. 4, p.100556
Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport Daniele Bizzarri, Erik B van den Akker, Marcel J T Reinders, René Pool, Marian Beekman, Nico Lakenberg, Nicolas Drouin, Kelly E Stecker, Albert J R Heck, Edward F Knol, Jeannette M Vergeer, M Arfan Ikram, Mohsen Ghanbari, Alain J van Gool, Joris Deelen, Bbmri-Nl, Dorret I Boomsma, P Eline Slagboom
Immunity and Ageing, 2025, vol. 22
Exploring Siglecs J S H Schaapherder, K C M Verhoeckx, A M Ehlers, E F Knol, A C Knulst, L A P M Meulenbroek
Clinical and Experimental Allergy, 2025, vol. 55, p.889-900
Basophil Activation Test Mariona Pascal, Jitesh Chauhan, Edward Knol, Rodolfo Bianchini, Mariana Castells, Leticia De Las Vecillas, Karin Hartmann, Elena Izquierdo, Uta Jappe, Teodorikez-Wilfox Jimenez-Rodriguez, Francesca Levi-Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F Santos, Erika Jensen-Jarolim, Christoph Bergmann, Sophia N Karagiannis, Heather J Bax
Allergy, 2025, vol. 80, p.2097-2112